Gene Information

Name : murD (NMV_0462)
Accession : YP_005877986.1
Strain : Neisseria meningitidis 8013
Genome accession: NC_017501
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoylalanine--D-glutamate ligase (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; D-glutamic acid adding enzyme)
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.2.9
Position : 437706 - 439043 bp
Length : 1338 bp
Strand : +
Note : Evidence 2b : Function of strongly homologous gene; Product type e : enzyme

DNA sequence :
ATGACTTTCCAAAACAAAAAAATCCTCGTCGCCGGACTTGGCGGCACGGGTATTTCCATGATTGCCTACCTGCGCAAAAA
CGGCGCGGAGGTTGCTGCGTATGATGCGGAGCTGAAGCCGGAACGCGTGTCGCAAATCGGTAAGATGTTTGACGGGCTGG
TGTTTTACACGGGCCGTCTGAAAGATGCGCTGGACAACGGTTTCGATATTCTGGCGCTCAGTCCCGGCATCAGCGAGCGG
CAGCCGGATATCGAGGCGTTCAAGCAAAACGGCGGACGCGTGTTGGGCGACATCGAATTGCTGGCGGACATTGTGAACCG
CCGCGGCGACAAGGTAATTGCGATTACCGGCAGCAACGGCAAAACCACGGTAACGAGCCTGGTCGGCTATCTCTGTATCA
AGTGCGGGCTGGATACCGTTATCGCGGGCAATATCGGCACGCCGGTTTTGGAGGCGGAATGGCAGCGCGAAGGCAAAAAG
GCGGACGTGTGGGTGTTGGAGCTTTCCAGCTTCCAACTGGAAAACACCGAAAGCCTGCGCCCGACTGCGGCGACGGTGCT
GAACATTTCCGAAGACCATCTCGACCGCTACGACGACTTGCTCGACTACGCGCATACCAAAGCCAAGATTTTCCGTGGCG
ATGGCGTTCAGGTTTTGAATTCAGACGACGTGTTCTGCCGCGCCATGAAACGGGCAGGGCGTGAAGTGAAATGGTTTTCG
TTGGAACACGAAGCCGATTTTTGGTTGGAACGCGAGACAGGCCGCCTGAAACAAGGCAATGAAGATTTGATTGCCACGCA
AGATATTCCGTTGCAAGGCTTGCACAACGCCACTAACGTGATGGCTGCCGTTGCCTTGTGCGAAGCCGTCGGTTTGCCGC
GCGAAGCATTGCTTGAACACGTCAAAACCTTCCAAGGCCTGCCGCACCGCGTGGAAAAAATCGGCAAGAAAAACGGCGTG
GTATTCATTGATGACAGCAAAGGCACGAATGTCGGCGCGACCGCCGCCGCGATTACCGGTTTGCAAAATCCGCTCTTCGT
GATTTTAGGCGGCATGGGCAAAGGGCAGGACTTCACGCCTCTGCGCGACGCGCTTGCCGGCAAGGCAAAAGGCGTGTTCC
TGATCGGTGTCGATGCGCCGCAAATCCGCCGCGATTTGGACGGCTGCGATCTGAATATGACCGACTGCGCCACTTTGGAA
GAAGCGGTTCAGAAGGCATATGCCCAAGCCGAAGCGGGCGACATCGTGTTGCTCAGCCCCGCCTGCGCAAGCTTCGATAT
GTTTAAAGGCTATGCGCACCGTTCGGAAGTGTTTATCGGGGCGTTTAAGGCTTTGTGA

Protein sequence :
MTFQNKKILVAGLGGTGISMIAYLRKNGAEVAAYDAELKPERVSQIGKMFDGLVFYTGRLKDALDNGFDILALSPGISER
QPDIEAFKQNGGRVLGDIELLADIVNRRGDKVIAITGSNGKTTVTSLVGYLCIKCGLDTVIAGNIGTPVLEAEWQREGKK
ADVWVLELSSFQLENTESLRPTAATVLNISEDHLDRYDDLLDYAHTKAKIFRGDGVQVLNSDDVFCRAMKRAGREVKWFS
LEHEADFWLERETGRLKQGNEDLIATQDIPLQGLHNATNVMAAVALCEAVGLPREALLEHVKTFQGLPHRVEKIGKKNGV
VFIDDSKGTNVGATAAAITGLQNPLFVILGGMGKGQDFTPLRDALAGKAKGVFLIGVDAPQIRRDLDGCDLNMTDCATLE
EAVQKAYAQAEAGDIVLLSPACASFDMFKGYAHRSEVFIGAFKAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 8e-58 41
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 8e-58 41