Gene Information

Name : guaA (NMV_2108)
Accession : YP_005879303.1
Strain : Neisseria meningitidis 8013
Genome accession: NC_017501
Putative virulence/resistance : Unknown
Product : GMP synthase [glutamine-hydrolyzing] (glutamine amidotransferase; GMP synthetase)
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 2024280 - 2025845 bp
Length : 1566 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme

DNA sequence :
ATGACCCAAGACAAAATCCTCATCCTCGACTTCGGTTCTCAAGTTACCCAGCTGATTGCCCGCCGCGTGCGCGAAGCCCA
CGTTTACTGCGAACTGCATTCCTTCGATATGCCTTTGGACGAAATCAAAGCCTTCAACCCCAAAGGCATCATCCTCTCTG
GCGGCCCCAATTCCGTTTACGAATCCGACTATCAAGCCGATACCGGTATTTTTGATTTGGGCATTCCGGTTTTGGGCATC
TGTTACGGCATGCAGTTTATGGCGCACCACTTGGGCGGCGAAGTGCAGCCCGGCAACCAGCGCGAATTCGGTTATGCGCA
AGTTAAAACCATAGACAGCGAGCTGACACGCGGCATTCAAGATGGTGAGCCAAACACACTCGACGTATGGATGAGCCACG
GCGACAAAGTGTCCAAACTGCCCGACGGTTTCGCCGTCATCGGCAACACCCCGTCCTGCCCGATTGCCATGATGGAAAAC
GCCGAAAAACAATTCTACGGCATCCAGTTCCACCCCGAAGTTACCCACACCAAACAAGGCCGCGCCCTGTTGAACCGCTT
TGTCTTGGATATTTGCGGCGCACAACCGGGCTGGACGATGCCGAACTACATCGAAGAAGCCGTTGCCAAAATCCGCGAAC
AGGTCGGCAGCGACGAAGTGATTTTAGGTTTGTCAGGCGGCGTAGACTCTTCCGTAGCCGCCGCGCTGATTCACCGCGCC
ATCGGCGACCAACTGACCTGCGTGTTCGTCGATCACGGTTTGTTGCGCCTGAACGAAGGCAAAATGGTGATGGATATGTT
CGCCCGCAACTTGGGCGTGAAAGTGATTCACGTCGATGCCGAAGGGCAGTTTATGGCGAAACTCGCCGGCGTTACCGACC
CTGAGAAAAAACGCAAAATCATCGGCGCGGAATTTATCGAAGTATTTGATGCCGAAGAGAAAAAACTCACCAACGCCAAA
TGGCTGGCGCAAGGCACGATTTACCCCGACGTAATCGAATCCGCAGGCGCGAAAACCAAAAAAGCCCACGCCATCAAATC
GCACCACAACGTCGGCGGTCTGCCCGAAAATATGAAGCTCAAGCTGCTTGAGCCGTTGCGCGACTTGTTTAAAGACGAAG
TGCGCGAACTGGGCGTTGCTTTGGGTCTGCCGCGCGAAATGGTGTACCGCCATCCGTTCCCCGGCCCCGGTTTGGGCGTG
CGCATCTTGGGCGAAGTGAAAAAAGAATACGCCGACTTATTGCGTCAAGCAGACGATATTTTCATCCAAGAATTACGCAA
CACCACCGACGAAAACGGCACATCTTGGTACGACCTGACCAGCCAAGCCTTCGCCGTGTTCCTGCCTGTGAAATCCGTCG
GCGTAATGGGCGACGGACGCACTTACGACTACGTCGTCGCACTGCGCGCAGTCATCACCAGCGACTTCATGACCGCACAC
TGGGCAGAACTGCCTTACTCACTGCTCGGACGCGTGTCCAACCGCATCATCAACGAAGTCAAAGGCATCAACCGCGTGGT
GTACGATGTCAGCGGCAAACCGCCTGCCACCATCGAGTGGGAATAA

Protein sequence :
MTQDKILILDFGSQVTQLIARRVREAHVYCELHSFDMPLDEIKAFNPKGIILSGGPNSVYESDYQADTGIFDLGIPVLGI
CYGMQFMAHHLGGEVQPGNQREFGYAQVKTIDSELTRGIQDGEPNTLDVWMSHGDKVSKLPDGFAVIGNTPSCPIAMMEN
AEKQFYGIQFHPEVTHTKQGRALLNRFVLDICGAQPGWTMPNYIEEAVAKIREQVGSDEVILGLSGGVDSSVAAALIHRA
IGDQLTCVFVDHGLLRLNEGKMVMDMFARNLGVKVIHVDAEGQFMAKLAGVTDPEKKRKIIGAEFIEVFDAEEKKLTNAK
WLAQGTIYPDVIESAGAKTKKAHAIKSHHNVGGLPENMKLKLLEPLRDLFKDEVRELGVALGLPREMVYRHPFPGPGLGV
RILGEVKKEYADLLRQADDIFIQELRNTTDENGTSWYDLTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVITSDFMTAH
WAELPYSLLGRVSNRIINEVKGINRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-136 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-136 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-136 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-118 50