Gene Information

Name : hemC (NMV_1888)
Accession : YP_005879142.1
Strain : Neisseria meningitidis 8013
Genome accession: NC_017501
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase (PBG; hydroxymethylbilane synthase; HMBS; pre-uroporphyrinogen synthase)
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.61
Position : 1815749 - 1816684 bp
Length : 936 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme

DNA sequence :
ATGAACCCGAAAAAACTCGTTATCGCCAGTCGCGAAAGCCTGCTTGCCATGTGGCAGGCAAAGCATATCCAAGGCCGTCT
GAAAGCCCTGTATCCCGATTGCGAAGTCGAGATTTTGGGCATGACCACGCGCGGCGACCAGATTTTGGACAAAACTTTGT
CAAAAGTCGGCGGTAAGGGCTTGTTTGTCAAAGAGTTGGAACAGGCTTTATATGACGGGCGCGCTGACTTGGCCGTGCAT
TCGATTAAAGATGTGCCGATGGATTTGCCTGAAGGTTTCGCGCTTGCAGCCATCGGCGAACGCGCCAATCCGTTTGACGC
GTTTGTGTCCAACCAATACGCGCGTTTGGAAGAAATGCCCAAAGGCGCCGTCGTAGGCACATCCAGCCTGCGCCGCGAAG
CCCAGTTGCGTGCGCGCTATCCGCATTTGGTTATCAAACCTTTGCGCGGCAATGTGCAAACCCGTTTGTCTAAACTCGAT
AACGGCGAATACGACGCAATTATCTTGGCTGCCGCCGGTTTGCAGCGTCTGGAATTGGACGGACGCATCCGCATGATTTT
GTCGGAATCCGACAGCCTGCCTGCCGCCGGACAAGGTGCATTGGGTATTGAAATTGCAGCGCATCGCGAAGATTTGTATG
AAGTCTTAAAGCCGTTGAACCACGATACCACACACGCCTGCGTTACGGCTGAACGCGCGTTGGCGCGCGCTTTGGGCGGA
AGCTGCCAAGTGCCGCTGGCGGCATATTGCACGGAAGAAAACGGCTTGCTGACCTTGCGCGGCTTGGTCGGTCATCCCGA
CGGTTCGGTTGTGTTGCGGGCGGACGCGCAAGCCCCTGCCGAATATGCCGACGCGCTCGGACGCGCTGTCGCTAAGAAAT
TGGCGGACGACGGTGCGCGGGAATTGATTGGAGCAGTATTGAATACGGAAAATTGA

Protein sequence :
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKGLFVKELEQALYDGRADLAVH
SIKDVPMDLPEGFALAAIGERANPFDAFVSNQYARLEEMPKGAVVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLD
NGEYDAIILAAAGLQRLELDGRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGARELIGAVLNTEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-70 56
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-70 56