Gene Information

Name : cblB (CVCAS_0745)
Accession : YP_005868138.1
Strain : Lactococcus lactis CV56
Genome accession: NC_017486
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase/cystathionine gamma-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.8
Position : 777744 - 778886 bp
Length : 1143 bp
Strand : +
Note : -

DNA sequence : 
ATGACAAGTATAAAAACGAAAGTAATTCATGGTGGTATTTCAACAGACAAGACAACAGGAGCAGTATCTGTTCCGATTTA
TCAAACGTCAACTTATAAACAAAACGGACTTGGACAACCTAAAGAATACGAATATTCACGTTCTGGAAATCCAACGCGTC
ATGCCTTGGAAGAATTAATTGCAGATTTAGAAGGTGGTGTTCAAGGATTTGCATTTAGTTCAGGACTTGCTGGAATTCAT
GCGGTTCTTTCGCTATTTTCTGCAGGAGATCATATCATTTTAGCTGATGATGTTTATGGTGGAACTTTCCGTTTGATGGA
TAAAGTGCTGACAAAGACAGGGATTATTTATGATTTAGTTGATTTGAGTAATCTTGATGACTTGAAAGCGGCTTTTAAAG
AAGAAACGAAAGCTATTTATTTTGAAACTCCTTCAAATCCTTTATTAAAAGTTTTGGACATTAAGGAAATTTCAGCAATT
GCTAAAGCTCATGATGCCTTAACACTGGTGGATAATACCTTTGCGACACCGTATTTACAACAACCAATTGCTTTAGGAGC
TGATATTGTTTTGCATTCCGCAACGAAATATTTAGGTGGACATTCAGATGTAGTGGCAGGACTAGTTACAACCAATTCAA
AAGAACTCGCCAGCGAAATTGGCTTTTTACAAAATTCAATTGGGGCGGTTCTTGGACCACAAGACAGCTGGTTAGTGCAA
AGAGGTATTAAAACACTTGCGCTTCGGATGGAGGCTCATTCGGCAAATGCTCAAAAAATTGCTGAGTTTTTAGAAACTTC
TAAAGCCGTCTCAAAAGTTTATTATCCAGGTCTTAATAGCCATCCGGGGCATGAAATTGCTAAAAAACAAATGTCTGCCT
TTGGAGGGATGATTTCATTTGAATTAACGGATGAAAATGCCGTCAAAGATTTTGTTGAAAACTTGAGCTATTTTACGTTG
GCTGAATCACTAGGTGGCGTTGAATCTTTAATTGAAGTGCCAGCAGTGATGACTCATGCTTCTATTCCAAAAGAACTTCG
TGAAGAAATTGGGATTAAGGATGGCCTAATTCGTCTATCAGTAGGGGTTGAAGCAATTGAAGATTTACTGACAGATATCC
AAGAAGCACTTGAAAAAAAATAA

Protein sequence : 
MTSIKTKVIHGGISTDKTTGAVSVPIYQTSTYKQNGLGQPKEYEYSRSGNPTRHALEELIADLEGGVQGFAFSSGLAGIH
AVLSLFSAGDHIILADDVYGGTFRLMDKVLTKTGIIYDLVDLSNLDDLKAAFKEETKAIYFETPSNPLLKVLDIKEISAI
AKAHDALTLVDNTFATPYLQQPIALGADIVLHSATKYLGGHSDVVAGLVTTNSKELASEIGFLQNSIGAVLGPQDSWLVQ
RGIKTLALRMEAHSANAQKIAEFLETSKAVSKVYYPGLNSHPGHEIAKKQMSAFGGMISFELTDENAVKDFVENLSYFTL
AESLGGVESLIEVPAVMTHASIPKELREEIGIKDGLIRLSVGVEAIEDLLTDIQEALEKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-96 55
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-98 55
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 9e-75 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cblB YP_005868138.1 cystathionine beta-lyase/cystathionine gamma-lyase BAC0207 Protein 2e-72 45