Gene Information

Name : metC (HN6_00023)
Accession : YP_005863165.1
Strain : Lactobacillus salivarius CECT 5713
Genome accession: NC_017481
Putative virulence/resistance : Resistance
Product : Cystathionine beta-lyase / Cystathionine gamma-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.1
Position : 33191 - 34333 bp
Length : 1143 bp
Strand : +
Note : -

DNA sequence : 
ATGAAATTTGAAACAAAATTAATTCATGGCGGACAAAGTGAAGATCAAGCAACAGGAGCAGTATCAATCCCTGTATATCG
TTCATCAACATTCCATCAATATGAGTTGGGTGGTAATCCTAAGTGGGAATACAGTCGTACAGGAAATCCTACACGTGCAG
CCTTAGAAGCGTTGATTGCTGATTTAGAGGGTGGAGTAGCTGGATTTGCCTTTGCTTCAGGTTCAGCAGCAATTCATGCT
ACATTCTCTATGTATTCAGCTCATGATCATTTTATCGTAGGAAGTGACGTTTATGGTGGAACTTTCCGTTTGATAAATAA
AGTGTTGAAACGATTTGGTTTAGAATTTACAGTTGTTGATATGCAAGATTTGGCAGCAATTGAAAATGCAATTCAAGATA
ACACAGTGGCAATCTACTTTGAAACACCAACTAATCCTTTGTTACAGATTGCAGATATTTCAGCTATTACAAAGATTGCT
AAGAAACATAATTTAAAGACAATCGTTGATAATACTTTCGCAACTCCATACAACCAAAGACCACTTGAATTAGGTGCTGA
TATTGTAGTGCATTCGGCTACTAAATATTTAGGTGGACATAGCGATGTAGTAGCAGGTTTAGCAGTTACTAGCGACGAAG
AAATCGCAGAAAAACTAGCATTTCTACAAAATTCAATCGGTAGTACATTAGGACCAGATGATAGCTGGTTGATCCAAAGA
GGAATTAAGACATTAGGTGCTAGAATGAGAGTTCATCATGCTAATACTGAGGCTATAATTAAGTTTTTAGAAAATGATGG
TCGCGTTGCAAGAATTCTTTATCCTGGTTTGCCTGACTTTCCTGGATATGAAGTTGCTAAGAGACAAATGGATCATTTTG
GAGCGATGATTTCTTTTGAATTACAAGAAGGATTAGATACTAAAAAGTTTGTTGAAAGTTTGAAAGTAATTTCTCTTGCC
GAAAGTTTAGGTGGAATTGAAAGTTTAATTGAAGTTCCATCAGTAATGACACATGGCTCAATTCCTAGAGAAATTCGTTT
GGAAAATGGAATTAAAGATGAATTGATTCGTTTGTCAGTAGGAATTGAAGATGAAGAAGATTTGATTGATGATTTGAAAC
AAGCTTTGGATAAGATTGGATAA

Protein sequence : 
MKFETKLIHGGQSEDQATGAVSIPVYRSSTFHQYELGGNPKWEYSRTGNPTRAALEALIADLEGGVAGFAFASGSAAIHA
TFSMYSAHDHFIVGSDVYGGTFRLINKVLKRFGLEFTVVDMQDLAAIENAIQDNTVAIYFETPTNPLLQIADISAITKIA
KKHNLKTIVDNTFATPYNQRPLELGADIVVHSATKYLGGHSDVVAGLAVTSDEEIAEKLAFLQNSIGSTLGPDDSWLIQR
GIKTLGARMRVHHANTEAIIKFLENDGRVARILYPGLPDFPGYEVAKRQMDHFGAMISFELQEGLDTKKFVESLKVISLA
ESLGGIESLIEVPSVMTHGSIPREIRLENGIKDELIRLSVGIEDEEDLIDDLKQALDKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-75 52
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-76 52
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-62 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_005863165.1 Cystathionine beta-lyase / Cystathionine gamma-lyase BAC0207 Protein 7e-66 45