Gene Information

Name : guaA (LC2W_2110)
Accession : YP_005857026.1
Strain : Lactobacillus casei LC2W
Genome accession: NC_017473
Putative virulence/resistance : Unknown
Product : GMP synthase large subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2039828 - 2041381 bp
Length : 1554 bp
Strand : -
Note : -

DNA sequence :
GTGGCAAATGACCAGAACAAGGATTACGACAAGATCATCGTCCTCGATTATGGCAGTCAGTATAATCAATTGATCACCCG
GCGAATCCGGGAATTTGGGATTTACTCTGAATTAAAGCCTCATACGATCACGGCAGCGGAAGTCAAGAAGATTGCGCCTA
AAGGCATTATCTTCTCAGGCGGCCCTAACAGTGTGTATGACGAAGGCGCGTTAGGTGTTGATGAGGATCTTTTCAAGCTC
GGCATTCCGATTCTGGGTGTCTGTTATGGCATGCAGCTGATGGCACAACGGCTCGGTGGGGATGTTGAACCGGCTGATAA
CCGTGAATACGGCAAAGCGGACATTGAAGTCACCGATGACAGCGCCAAGCTTTTCCGCGATTTGCCAAAAGATCAAACCG
TCTGGATGAGCCACGGCGACCTCGTGACCCGCGTACCAGAAGGCTTCCGGCGAACCGCAACCAGCATCAACTGCCCAATC
AGTGCCATGGATGACGATGATCGTAAATTCTACGGCATCCAATTCCATGCTGAAGTTCAAAATACGCAATATGGCCATGA
AATCCTCCACCATTTTGCCTTCGACATCTGCAAGGCTGAAGCTAACTGGAGCATGGACGACTTCATCACCAAACAAATCG
ACAAGATTCGGGCAGAAGTCGGCGACAAGCGCGTTCTCCTCGGTCTTTCTGGCGGGGTTGATTCATCCGTAGTCGGCGTG
CTCCTGCACAAAGCCATCGGCACCCAGCTGACCAGTATTTTTGTTGATCACGGCTTGCTGCGTAAGGGCGAAGCTGATCA
AGTCATGGAAAGCCTCAAAGGCAAGTTTGGTCTGAACATCATCAAGGTCAACGCCAAAGATCGCTTCCTCGGCGACCTCA
AAGGGGTTACTGATCCTGAAAAGAAACGTAAAATCATCGGTCGCGACTTCATCGAAGTTTTCAATGAAGAAGCAGCCAAG
CTCAACGGCATCGATTTCTTAGCCCAAGGCACGCTCTACACCGATGTGGTTGAATCCGGTACCGACACCGCCCAGACCAT
CAAGTCTCACCACAATGTTGGCGGCCTGCCAGAAGACCTCAAGTTCAAGCTAATCGAACCTCTGAACAAGCTCTTCAAAG
ATGAAGTCCGCGAACTCGGCGAAAAACTCGGCATGCCCCACGCCCTCGTCTGGCGTCAACCATTCCCTGGCCCAGGCCTC
GGCATCCGCGTCATCGGCGAAGTCACCGAAGATAAACTCGAAATCGTTCGCGATTCCGATTATATCCTCCGTGAAGAAAT
CGCTAAGCATGGCTTGGACAAGGACATTTGGCAATACTTTACCGTCTTACCAGGCTTCCGATCCGTCGGTGTCATGGGCG
ATGGCCGAACCTACGACTACACCATTGGCATCCGCGCCATCACCTCAATTGACGGCATGACCGCCGACTTTGCCCGGATC
AACTGGGATGTCCTACAGGAAATCTCAAGCCGGATTGTGAATGAAGTTAAGAATGTTAATCGGGTGGTTTATGATATTAC
TTCCAAGCCGCCGGCAACGATTGAGTGGGAATAG

Protein sequence :
MANDQNKDYDKIIVLDYGSQYNQLITRRIREFGIYSELKPHTITAAEVKKIAPKGIIFSGGPNSVYDEGALGVDEDLFKL
GIPILGVCYGMQLMAQRLGGDVEPADNREYGKADIEVTDDSAKLFRDLPKDQTVWMSHGDLVTRVPEGFRRTATSINCPI
SAMDDDDRKFYGIQFHAEVQNTQYGHEILHHFAFDICKAEANWSMDDFITKQIDKIRAEVGDKRVLLGLSGGVDSSVVGV
LLHKAIGTQLTSIFVDHGLLRKGEADQVMESLKGKFGLNIIKVNAKDRFLGDLKGVTDPEKKRKIIGRDFIEVFNEEAAK
LNGIDFLAQGTLYTDVVESGTDTAQTIKSHHNVGGLPEDLKFKLIEPLNKLFKDEVRELGEKLGMPHALVWRQPFPGPGL
GIRVIGEVTEDKLEIVRDSDYILREEIAKHGLDKDIWQYFTVLPGFRSVGVMGDGRTYDYTIGIRAITSIDGMTADFARI
NWDVLQEISSRIVNEVKNVNRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-169 67
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-168 67
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-169 67
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-124 50