Gene Information

Name : guaA (LAB52_01250)
Accession : YP_005853240.1
Strain : Lactobacillus amylovorus GRL1118
Genome accession: NC_017470
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 248626 - 250176 bp
Length : 1551 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
GTGGCTAAAAATCTAGACGATTTTGACAAGATTATTGTTCTTGACTTTGGTAGTCAATACAATCAATTAATCACTCGACG
CATTCGTGATTTTGGCATCTACTCAGAACTTTTGCCCCACGATCTTTCAATTGACAGGATCAAGGAAATGAATCCTAAAG
GAATTATTTTCTCAGGTGGTCCAAACAGTGTTTATGACGATGGTGCTTTGAAGGTTGATCCTGAAATCTTTAAATTAGGT
ATTCCTATTTTGGGTATTTGTTACGGGATGCAACTGATGAGCTATGACTTGGGCGGCAAGGTTGAACCTGCTGATAACAA
GGAATACGGTAGAGCAAACATTACTGTCGAAGATCCAGACAGTGCTTTATTCAAGGGCTTACCAAGCAAGCAATACGTTT
GGATGAGCCACGGTGACTTAGTAACCCAAGCACCTAAGGGCTTTGAAGTAACTGCTTCAAGCAAGAACTGTCCAATCGCT
GCAATTGATAACTCAGACAAGAAGTTCTACGGTATCCAATTCCACGCTGAAGTTCGTAACTCAGAATATGGTTTGGACAT
CTTGAAGCGTTTTGCCTTTGACGTTTGTGGTGCCGTAGCTAACTGGACGATGGATGACTTCATCGACATGAAGATTGGCG
AAATCCGTAAGGAAGTCGGTGACAAGAAGGTTATCTTAGGTCTTTCTGGTGGTGTTGACTCAAGTGTTACTGCCACTTTG
CTTCACAAGGCAATTGGTAATCAATTGACTGCTATTTTCGTTGATCACGGGATGCTTCGTAAGGACGAAGGCGACCAAGT
TATGAAGGCTTTGAACAAGGACCTCGGTGTTAACATTATCCGTGTTAACGCACAAAAGAGATTCTTGGACAAGCTTAAGG
GCGTAACTGATCCTGAAAAGAAGCGTAAGATCATCGGTAAGGAATTTATCGAAGTCTTCAACGAAGAAGCTAAAAAGATT
AAGGATGTTGACTTCTTAGCACAAGGTACTTTGTACACTGACGTCATTGAGTCAGGTACTAATACTGCTCAAACTATCAA
ATCACACCACAACGTAGGTGGTCTTCCTAAGGACATGCACTTTAAACTTATTGAACCACTTCGCAAGTTGTTCAAGGATG
AAGTTCGTGAACTTGGTGAAAAACTTGGTATTCCACATGACTTAGTATGGCGTCAACCATTCCCAGGTCCAGGTCTTGGT
ATTCGTGTTCTTGGCGAAGTTACTGAACCTAAGCTGAAGATCGTGCGTGAATCTGATGCGATTTTGCGTGACGAGATTAA
GAAAGCTGGATTGCAAGAAAAGATTTGGCAATACTTTACTGTTTTGCCAGGAATTCGTTCAGTTGGTGTGATGGGTGATG
GTCGTACTTATGACTACACCATTGGTATTCGTGCCGTAACTTCAATTGACGGTATGACTGCAGACTTTGCGAAAATTCCA
TGGGACGTACTTGGTCACATTTCAGATAGAATCGTTAACGAAGTAGATAACGTTAACCGTGTAGTTTACGATGTAACGAG
TAAGCCACCTTCCACTATTGAATGGGAATAG

Protein sequence :
MAKNLDDFDKIIVLDFGSQYNQLITRRIRDFGIYSELLPHDLSIDRIKEMNPKGIIFSGGPNSVYDDGALKVDPEIFKLG
IPILGICYGMQLMSYDLGGKVEPADNKEYGRANITVEDPDSALFKGLPSKQYVWMSHGDLVTQAPKGFEVTASSKNCPIA
AIDNSDKKFYGIQFHAEVRNSEYGLDILKRFAFDVCGAVANWTMDDFIDMKIGEIRKEVGDKKVILGLSGGVDSSVTATL
LHKAIGNQLTAIFVDHGMLRKDEGDQVMKALNKDLGVNIIRVNAQKRFLDKLKGVTDPEKKRKIIGKEFIEVFNEEAKKI
KDVDFLAQGTLYTDVIESGTNTAQTIKSHHNVGGLPKDMHFKLIEPLRKLFKDEVRELGEKLGIPHDLVWRQPFPGPGLG
IRVLGEVTEPKLKIVRESDAILRDEIKKAGLQEKIWQYFTVLPGIRSVGVMGDGRTYDYTIGIRAVTSIDGMTADFAKIP
WDVLGHISDRIVNEVDNVNRVVYDVTSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-174 68
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-174 68
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-174 68
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-131 51