Gene Information

Name : guaA (LBHH_0237)
Accession : YP_005849460.1
Strain : Lactobacillus helveticus H10
Genome accession: NC_017467
Putative virulence/resistance : Unknown
Product : Bifunctional GMP synthase/glutamine amidotransferase protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 251206 - 252783 bp
Length : 1578 bp
Strand : +
Note : -

DNA sequence :
ATGTTTAGTGAAAAGAGGGAGTACATAGTGGCTAAAAATCTAGACGATTTTGATAAAATTATTGTTCTTGACTTTGGTAG
TCAATACAACCAATTGATTACTCGACGCATTCGTGACTTCGGTATTTATTCAGAACTTTTACCTCACGATCTTTCTATTG
CCAAGATTAAAGAAATGCATCCCAAGGGCATTATTTTTTCTGGTGGTCCTAACAGTGTTTACGATGATGGTGCATTAAAA
GTAGATCCAGAAATCTTCAAGTTGGGTATCCCAATTTTAGGTATTTGTTATGGAATGCAGCTCATGTCATATGACTTAGG
CGGTAAGGTTGAACAGGCTGAGAACAAAGAATATGGTCGTGCTAATATTACCGTTGAAGATCCTGATAGTGCATTGTTTA
AGGGCCTGCCAAGTAAGCAATATGTTTGGATGAGTCATGGTGATTTGGTAACTAAGGCTCCTAACGGCTTTGAGGTAACT
GCTTCAAGCAAGAACTGTCCAATTGCTGCTATTGCTAATCCAGATAAAAAGTTTTACGGTATTCAATTCCACGCAGAAGT
ACGTAATTCAGAATATGGTTTAGACATCTTGAAGCACTTTGCCTTTGATGTTTGTGGTGCTGATGCTAACTGGACCATGA
ACGACTTTATCGACATGAAGGTTGACGATATTCGTAAAGAAGTTGGCGACAAGAAGGTTATCTTAGGACTTTCAGGCGGT
GTGGATTCCAGCGTTACTGCTACTCTTTTACACAAAGCAATTGGCGATCAATTGACTGCAATTTTCGTTGATCACGGGAT
GCTGCGTAAAGATGAAGGCGACCAAGTAATGCAAGCCTTGAATAAGGATCTTGGCGTCAACATTATTCGCGTTAACGCAC
AAAAGAGATTTTTGGACAAGTTAAAGGGTGTTACTGATCCTGAACAAAAGCGTAAGATCATCGGTAAGGAATTTATCGAA
GTCTTCAATGAAGAAGCTAAGAAGTTAAAGGATGTAAACTTCTTAGCTCAAGGTACGCTTTATACTGATGTCATTGAATC
AGGGACTAACACTGCCCAAACTATCAAGTCTCACCACAACGTTGGTGGCCTTCCTAAGGACATGCACTTCAAGTTAATTG
AACCCCTTCGTAAGTTGTTCAAGGATGAAGTTCGTGAACTTGGTGAAAGATTAGGCATTCCACATGACTTAGTATGGCGT
CAGCCATTCCCAGGTCCAGGTCTTGGTATTCGCGTGCTTGGCGAAGTTACAGAAGACAAGCTCAAGATTGTGCGTGATTC
CGATGCGATTTTGCGTGAAGAAATCAAGAAGGCTGGTTTGCAAGAAAAGATCTGGCAATACTTCACAGTTTTACCAGGTA
TTCGCTCAGTTGGCGTTATGGGTGACGGCCGTACTTATGACTATACCATTGGTATTCGTGCCGTTACTTCAATTGATGGG
ATGACTGCTGATTTTGCCCAAATTCCATGGGATGTACTTGGTCATATTTCAGATAGAATCGTCAATGAAGTAGATAACGT
TAACCGTGTAGTCTACGATGTGACGAGTAAGCCACCTTCAACTATTGAATGGGAATAA

Protein sequence :
MFSEKREYIVAKNLDDFDKIIVLDFGSQYNQLITRRIRDFGIYSELLPHDLSIAKIKEMHPKGIIFSGGPNSVYDDGALK
VDPEIFKLGIPILGICYGMQLMSYDLGGKVEQAENKEYGRANITVEDPDSALFKGLPSKQYVWMSHGDLVTKAPNGFEVT
ASSKNCPIAAIANPDKKFYGIQFHAEVRNSEYGLDILKHFAFDVCGADANWTMNDFIDMKVDDIRKEVGDKKVILGLSGG
VDSSVTATLLHKAIGDQLTAIFVDHGMLRKDEGDQVMQALNKDLGVNIIRVNAQKRFLDKLKGVTDPEQKRKIIGKEFIE
VFNEEAKKLKDVNFLAQGTLYTDVIESGTNTAQTIKSHHNVGGLPKDMHFKLIEPLRKLFKDEVRELGERLGIPHDLVWR
QPFPGPGLGIRVLGEVTEDKLKIVRDSDAILREEIKKAGLQEKIWQYFTVLPGIRSVGVMGDGRTYDYTIGIRAVTSIDG
MTADFAQIPWDVLGHISDRIVNEVDNVNRVVYDVTSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-175 68
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-175 68
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-175 68
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-131 51