Gene Information

Name : clpB (HMPREF9231_1358)
Accession : YP_005838660.1
Strain : Gardnerella vaginalis HMP9231
Genome accession: NC_017456
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone protein ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1658303 - 1660897 bp
Length : 2595 bp
Strand : -
Note : -

DNA sequence :
ATGGAACAAAAGTTTACAACCTTAGCGCAAGATGCATTAAGCGATGCTGTGCAAAGCGCGGCGGCAGCTGGCAATGCGCA
AGTAGATACGTTACATTTGGCAGATGCCTTACTTCGCCAAGAGCAAGGCGTAGTGCGCGCGCTTATTGCACAGGCAGGGG
CGGACGCGCAACAAATCGGCGCTGAAATTCGCAACGCATTAGTGGCACTGCCTTCATCTACTGGCTCAACTACAACTAAG
CCAGACGCAAGCCGTCAGCTTTTAGCTGCGCTAAGCCAGGCAGAAAAAGAAATGCGCACAATGGGAGACGAATACGTTTC
TACAGAGCACATGCTTATTGGCATAGTTGCAAGCGCGCCGAATGCTGTTGCGGATATTTTCAAAAAGCACAATGTTTCTG
CAGACGCGTTGCGCAAGGCTGTGCCAACTGTACGCGGAGGCGCGAAAGTTACAAGCCCAGACGCGGAAGGCAACTACAAA
GCGCTCGAAAAATATTCGGTTGATATGACTGCGCGCGCTCGCGAAGGAAAGCTTGACCCTGTGATTGGGCGAGATCAGGA
GATTCGCCGCGTGATTCAAATTCTTTCTCGCAGAACTAAGAACAATCCTGTGCTAATTGGCGAGCCAGGCGTTGGAAAAA
CGGCAGTTGTAGAAGGATTGGCTCAGCGAATTGTGGCAGGAGATGTGCCTACGACTTTGCAAAACAAGCGTCTTATCAGC
CTCGACTTGGCTTCGATGGTTGCAGGTTCGAAGTATCGCGGCGAGTTTGAGGAACGCTTAAAGGCAGTGTTGAAGGAAAT
TCAGCAATCAGACGGTCAAATTATTACGTTTATTGATGAGATTCACACTGTTGTTGGCGCAGGATCTGCAGAAGGTTCAA
TGGATGCTGGCAATATGCTTAAGCCAATGCTTGCGCGCGGTGAGCTGCGCTTGGTTGGCGCGACTACTCTTAATGAGTAT
CGTGAGCATATTGAAAAGGATTCCGCTCTTGAGCGCAGATTCCAGCAAGTATTCGTTGGCGAGCCATCTGTTGAAGATAC
GGTGACGATTTTGCGCGGACTTAAGCAACGTTACGAAGCGCATCATAAGGTGACGATTAGTGACGATGCAATCGTAGCTG
CAGCAACGCTTTCAAACCGCTATATTACTGGCAGACAACTTCCAGATAAGGCGATTGATTTGGTTGATGAAGCGGCAGCT
CACTTGCGTATGGAGCTTGATTCTCAGCCAGAAGAAATCGACGAATTGCAGCGCAAAGTTACGCGTCTTGAAATGGAAGA
AATGCAATTAAAGAAAGCGGAAGATGCTGCTGCTAAAGAACGCTTAGAAAAGTTGCAAGAAGAATTAGCAAACTCGCGCG
AAAAGCTTACTGGTTTGAAAGCGCGTTGGGATGCGGAAAAGGCTGGTCACAACAAGGTTGGTGATTTGCGAGCGCAACTC
GATGCTAAGCGCGTAGAAGCCGACAAATTCACGCGTGAAGGCAATTTGGAGCAAGCAAGCCGTATTTTGTATGGCGAAAT
CCCAAGCATTCAAAAAGCTTTGGAAGAAGCGGAATCACAGGCTGCTAATGCTAAGAGTGAAGCGAAAGAGCCAATGGTTC
CAGACCAGGTTGATGCCGATTCTATTGCAGGAGTTGTTAGCGAATGGACGGGCATTCCTGTTGGTCGCTTAATGCAAGGC
GAAAATGAGAAGCTGCTCAACATGGAAAAGGAGCTTTCTAAGCGCGTTGTTGGCCAAAGCGAAGCAATCCGCGCTATAGC
GGATGCTGTGCGCAGAAGCCGTGCTGGAATTGCAGACCCGAATCGCCCAACTGGTTCGTTCCTATTCTTGGGTCCTACTG
GCGTTGGTAAGACGGAGCTTGCAAAGGCTCTTGCCGACTTCTTGTTTGACGACGAGCGCGCAATGGTTCGCATTGATATG
AGCGAGTACATGGAAAAGGCTTCCGTTTCACGGCTTATAGGTGCTGCTCCTGGTTACATTGGCTATGAGGAAGGCGGCCA
GCTTACTGAAGCCGTGCGACGCCGCCCGTATTCTGTAGTGCTTTTTGACGAAATTGAGAAGGCACATCCAGAAGTATTCG
ACGTTTTGTTGCAGGTTTTGGACGATGGTCGTTTGACTGACGGACAAGGTAGAACGGTTGATTTTACGAATACGATTTTG
ATTATGACATCAAACTTGGGTTCGCAATTCCTTGTGCAAGAGGGCTTGGATGATGATGCTAAGCGCAAGGCTGTTATGAA
CGCTGTTCACGCTGAGTTTAAGCCAGAGTTCATCAACCGTTTGGATGAGCTTGTTATGTTCCATCCGTTGAGCCGCGAAG
AGCTTGGCGGAATTGTGGATATTCAAGTTCGTCAAGTGGCTGCACGCTTGAGTGATCGCCGTATTAGCTTGGATGTGAGT
GATTCTGCTCGCGCTTGGCTTGCGGAGCATGGCTATGATCCAGTTTACGGTGCTCGTCCGTTGCGTAGATTGGTTCAAAC
GGAAATTGGCGATCAACTTGCGCGATTGTTGCTTTCTGGCAAGGTGCATGATGGGGCTCGCGTAGTTGCGGATTGTGAGA
ATACTAGCGACCATGTAACCCTAAAGATTGCGTAG

Protein sequence :
MEQKFTTLAQDALSDAVQSAAAAGNAQVDTLHLADALLRQEQGVVRALIAQAGADAQQIGAEIRNALVALPSSTGSTTTK
PDASRQLLAALSQAEKEMRTMGDEYVSTEHMLIGIVASAPNAVADIFKKHNVSADALRKAVPTVRGGAKVTSPDAEGNYK
ALEKYSVDMTARAREGKLDPVIGRDQEIRRVIQILSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPTTLQNKRLIS
LDLASMVAGSKYRGEFEERLKAVLKEIQQSDGQIITFIDEIHTVVGAGSAEGSMDAGNMLKPMLARGELRLVGATTLNEY
REHIEKDSALERRFQQVFVGEPSVEDTVTILRGLKQRYEAHHKVTISDDAIVAAATLSNRYITGRQLPDKAIDLVDEAAA
HLRMELDSQPEEIDELQRKVTRLEMEEMQLKKAEDAAAKERLEKLQEELANSREKLTGLKARWDAEKAGHNKVGDLRAQL
DAKRVEADKFTREGNLEQASRILYGEIPSIQKALEEAESQAANAKSEAKEPMVPDQVDADSIAGVVSEWTGIPVGRLMQG
ENEKLLNMEKELSKRVVGQSEAIRAIADAVRRSRAGIADPNRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRIDM
SEYMEKASVSRLIGAAPGYIGYEEGGQLTEAVRRRPYSVVLFDEIEKAHPEVFDVLLQVLDDGRLTDGQGRTVDFTNTIL
IMTSNLGSQFLVQEGLDDDAKRKAVMNAVHAEFKPEFINRLDELVMFHPLSREELGGIVDIQVRQVAARLSDRRISLDVS
DSARAWLAEHGYDPVYGARPLRRLVQTEIGDQLARLLLSGKVHDGARVVADCENTSDHVTLKIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-159 47
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-108 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-108 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_005838660.1 ATP-dependent chaperone protein ClpB VFG2084 Protein 2e-111 44
clpB YP_005838660.1 ATP-dependent chaperone protein ClpB VFG2076 Protein 2e-119 44