Gene Information

Name : HMPREF9231_1348 (HMPREF9231_1348)
Accession : YP_005838650.1
Strain : Gardnerella vaginalis HMP9231
Genome accession: NC_017456
Putative virulence/resistance : Virulence
Product : thiol-activated cytolysin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1647709 - 1649259 bp
Length : 1551 bp
Strand : +
Note : -

DNA sequence :
ATGAAGAGTACAAAGTTCTACCGTAATGCAGCAATGTTGCTCCTCGCGGGCGCAACTATTGTTCCACAATGCTTAGCAGC
ACCAGCAATGGCCGCTCCTTCCGCTAAGGATTCTGAACCAGCTACATCTTGCGCAGCTAAGAAAGACTCGTTGAATAATT
ATTTGTGGGATTTGCAATACGATAAAACAAACATTCTCGCCCGTCATGGCGAAACCATTGAGAACAAATTCTCCAGCGAC
AGCTTCAACAAGAACGGTGAATTCGTTGTTGTTGAGCATCAGAAGAAGAACATCACCAATACAACTTCAAATTTGTCGGT
TACTTCCGCCAACGATGATCGCGTATACCCAGGTGCTCTTTTCCGTGCTGATAAGAATTTGATGGACAATATGCCAAGCC
TGATTTCTGCAAACCGCGCTCCAATAACGTTGAGCGTTGATTTGCCGGGATTCCACGGCGGCGAAAGTGCTGTAACTGTT
CAGCGCCCAACCAAGAGCTCTGTAACTTCCGCAGTGAACGGCTTAGTTTCTAAGTGGAATGCACAATATGGAGCAAGTCA
TCATGTTGCAGCTCGCATGCAGTACGATTCTGCAAGCGCACAAAGCATGAACCAGCTCAAGGCTAAGTTTGGTGCTGATT
TTGCCAAGATTGGTGTTCCGCTGAAGATTGATTTCGATGCAGTACACAAGGGTGAGAAGCAGACTCAAATTGTGAACTTC
AAGCAAACTTACTACACCGTAAGCGTTGATGCACCAGATAGCCCAGCAGATTTCTTTGCTCCTTGCACTACGCCAGACAG
CTTGAAGAACCGTGGCGTTGACAACAAGCGCCCACCAGTTTACGTGTCAAACGTAGCTTATGGTCGCTCAATGTACGTAA
AGTTCGATACCACCAGCAAGAGCACTGATTTCCAGGCTGCGGTAGAAGCAGCAATTAAGGGCGTAGAAATCAAGCCAAAC
ACCGAATTCCATCGCATTCTCCAGAATACTTCTGTTACTGCAGTGATTCTTGGTGGCAGCGCTAATGGTGCAGCTAAAGT
TATTACAGGCAATATCGATACGCTTAAGGCTTTGATTCAGGAAGGTGCAAATTTGAGCACCTCTAGCCCAGCGGTTCCAA
TTGCATACACCACTTCCTTCGTCAAGGATAACGAAGTAGCAACTTTGCAATCCAACAGCGATTATATTGAAACGAAGGTT
TCTTCTTATCGCAATGGCTACTTGACTTTGGACCACCGTGGAGCTTATGTAGCTCGCTACTACATCTACTGGGATGAGTA
CGGCACCGAAATTGACGGCACTCCTTACGTGCGTTCTCGCGCTTGGGAAGGCAATGGTAAGTATCGTACAGCTCACTTCA
ACACCACTATTCAGTTCAAAGGAAATGTACGCAATCTACGAATCAAGTTGGTTGAAAAGACTGGTTTGGTTTGGGAACCA
TGGCGCACAGTATATGACCGTTCTGATTTGCCACTAGTTCGTCAGCGTACTATTAGCAACTGGGGCACAACCTTGTGGCC
TCGCGTTGCTGAAACTGTAAAGAACGACTGA

Protein sequence :
MKSTKFYRNAAMLLLAGATIVPQCLAAPAMAAPSAKDSEPATSCAAKKDSLNNYLWDLQYDKTNILARHGETIENKFSSD
SFNKNGEFVVVEHQKKNITNTTSNLSVTSANDDRVYPGALFRADKNLMDNMPSLISANRAPITLSVDLPGFHGGESAVTV
QRPTKSSVTSAVNGLVSKWNAQYGASHHVAARMQYDSASAQSMNQLKAKFGADFAKIGVPLKIDFDAVHKGEKQTQIVNF
KQTYYTVSVDAPDSPADFFAPCTTPDSLKNRGVDNKRPPVYVSNVAYGRSMYVKFDTTSKSTDFQAAVEAAIKGVEIKPN
TEFHRILQNTSVTAVILGGSANGAAKVITGNIDTLKALIQEGANLSTSSPAVPIAYTTSFVKDNEVATLQSNSDYIETKV
SSYRNGYLTLDHRGAYVARYYIYWDEYGTEIDGTPYVRSRAWEGNGKYRTAHFNTTIQFKGNVRNLRIKLVEKTGLVWEP
WRTVYDRSDLPLVRQRTISNWGTTLWPRVAETVKND

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 2e-96 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HMPREF9231_1348 YP_005838650.1 thiol-activated cytolysin VFG1363 Protein 9e-129 53
HMPREF9231_1348 YP_005838650.1 thiol-activated cytolysin VFG2275 Protein 4e-90 42
HMPREF9231_1348 YP_005838650.1 thiol-activated cytolysin VFG0074 Protein 2e-96 41