Gene Information

Name : Hprae_0061 (Hprae_0061)
Accession : YP_005835380.1
Strain : Halanaerobium praevalens DSM 2228
Genome accession: NC_017455
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.11
Position : 77414 - 78607 bp
Length : 1194 bp
Strand : +
Note : COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR006237; KEGG: nth:Nther_2455 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; TIGRF

DNA sequence :
TTGGAAAAGAAAGATTTAGGAAAATTAGGATTTCAATCACTTTGTTGTCATGCTGGTCAACATGCAGATCCTCAAACTGG
TGCTCATAACACACCTATTTATCAAACATCTACTTTTGCCTTTCAAAATGTAGAAGACGGAGCGAAAAAGTTTGCTGGAG
AAAAAGAAGGATATATTTACACTAGATTAGGTAATCCAACTCAAACAGCTTTAGAAGAAAAAATGGCTGCTTTAGAAGGT
GCTGAAGCTGCAATTGCTACTGCATCTGGAATGGCGGCAATTTCTGCATCTGTAATGGCTGTTGCTTTTGCTGGAGATCA
CATTCTGGCCCATGATTGTCTCTATGGATGTACTCATTCCTTAATGGAAGAAATATTACCAAGATATGGAATTGAAGTTA
CTTTTGCTGATTTATCTAATTTAGATAATGTTGATAAAAATCTACAAGATAATACAAAATTAGTTTATCTTGAAACACCA
TCTAATCCAACTCTTAACCTAGTTGATATTGAAGAAATTAGTAAAAAAGCTCATGCAGCTGGAGCAAAAGTTATAGCAGA
TAACACTTTTATGACTCCTTATTTACAAAATCCTTTAGCATTAGGAGCAGATATGGTTGTTCATAGTGCTACTAAATACA
TAGGTGGTCATGGAGATGCTATAGCAGGTGTGATTGCTGGTAATCAAGAAATGTTAGCTGATATTAGAATGACTACTCTT
AAAGACTTTGGTGGAATCATTAGTCCTTTTAATGCCTGGTTATTATTAAGAGGTCTTAAAACTCTACCTTTAAGAGTCGA
AAAACATAATCAAAATGCTATGGAAGTAGCTAAATTCTTAGAAAAACATGATAAAGTTGAAGAAGTATTTTTCCCAGGTT
TAGAAAGTCATCCTCAGCATGAATTAGCTAAAAAACAAGCCTCTGGTTTTGGTAGCATGATCAGTTTTGAATTAAAAGGT
GGTCATAGTGCAGGAGAAAAAATGATGAATAATGTTAATTTAGCTACTTTAGCTGTTAGTTTAGGTGATGTTGATACTTT
AATTCAGCACCCAGCTTCAATGACTCATGCTCCAGTACCGCGTGAAGAAAGATTAAAAGCTGGAATTACAGATGGTTTAG
TTAGAATTTCAATTGGAATTGAAGATTTAGATGATATTATAGCTGACCTTGACTCTGCTCTTGCAAAAATATAA

Protein sequence :
MEKKDLGKLGFQSLCCHAGQHADPQTGAHNTPIYQTSTFAFQNVEDGAKKFAGEKEGYIYTRLGNPTQTALEEKMAALEG
AEAAIATASGMAAISASVMAVAFAGDHILAHDCLYGCTHSLMEEILPRYGIEVTFADLSNLDNVDKNLQDNTKLVYLETP
SNPTLNLVDIEEISKKAHAAGAKVIADNTFMTPYLQNPLALGADMVVHSATKYIGGHGDAIAGVIAGNQEMLADIRMTTL
KDFGGIISPFNAWLLLRGLKTLPLRVEKHNQNAMEVAKFLEKHDKVEEVFFPGLESHPQHELAKKQASGFGSMISFELKG
GHSAGEKMMNNVNLATLAVSLGDVDTLIQHPASMTHAPVPREERLKAGITDGLVRISIGIEDLDDIIADLDSALAKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-52 45
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-50 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-47 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hprae_0061 YP_005835380.1 methionine gamma-lyase BAC0207 Protein 2e-63 47