Gene Information

Name : Hprae_0321 (Hprae_0321)
Accession : YP_005835637.1
Strain : Halanaerobium praevalens DSM 2228
Genome accession: NC_017455
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 370050 - 370727 bp
Length : 678 bp
Strand : +
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cth:Cthe_1288 two component transcriptional regulator; PFAM: response regulator receiver; transcriptiona

DNA sequence :
ATGGATAAAAAAAAGATTTTAATCATAGATGATGATCTGCAAATAACTAAAATTTTAAGAGATTATTTTAATTATGAAAA
TTTTGAAGTTTTTGTGGCTCATGATGGGCAAAAAGGTTTAGAAAAAATTAACAATTTAGAGATAGATATTATAATTTTAG
ATTTAATGCTGCCTAAAAAAAATGGTTTAGATATTTGCCGTCAATTAAAGCCCCATAACAAAATACCGATTATAATTTTG
AGTGCTAAAAATCGTGAAAATGATAGAATTAAAGGGCTTGAGTTAGGAGCAGATGATTATGTAACTAAACCATTTAGTCC
TAAAGAATTAGTTTTGCGGGTTAAAAACGTTTTAAAAAGAATTAATAATGATCAAGACCAAAATGAGCTTAGTTTTCCCG
ATTTAATAATTAATAAAGAGCAAAGATTAGTTAAGGTAAAAAAAGAAGAAATTGCTTTAGCACCTAAAGAATTTGATTTA
CTCTGGCAGCTGGCTTCTTCTCCGAAAACTGTTTTTAGTCGAGAAAAACTATTAGAGTTGGTCTGGGATTTCGATTATTT
TGGTGGGATTAGAACAGTTGATACCCATATTAAATCGATTCGAAATAAATTAGGGGCAGAAGTGGGTAATTATGTGCAGA
CTGTCTGGGGAATTGGTTATAAATTTGGAATCAAATAA

Protein sequence :
MDKKKILIIDDDLQITKILRDYFNYENFEVFVAHDGQKGLEKINNLEIDIIILDLMLPKKNGLDICRQLKPHNKIPIIIL
SAKNRENDRIKGLELGADDYVTKPFSPKELVLRVKNVLKRINNDQDQNELSFPDLIINKEQRLVKVKKEEIALAPKEFDL
LWQLASSPKTVFSREKLLELVWDFDYFGGIRTVDTHIKSIRNKLGAEVGNYVQTVWGIGYKFGIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 7e-27 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 3e-27 42
vanRB YP_001698483.1 regulatory protein Not tested Not named Protein 1e-26 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator FJ349556.1.orf0.gene Protein 4e-36 45
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator AF155139.2.orf0.gene Protein 8e-33 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_002952.2859905.p0 Protein 6e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_009782.5559369.p0 Protein 6e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_002951.3237708.p0 Protein 6e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_003923.1003749.p0 Protein 5e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_002758.1121668.p0 Protein 6e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_009641.5332272.p0 Protein 6e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_013450.8614421.p0 Protein 6e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_007793.3914279.p0 Protein 6e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_007622.3794472.p0 Protein 6e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_002745.1124361.p0 Protein 6e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator NC_012469.1.7685629. Protein 2e-30 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator AE000516.2.gene3505. Protein 7e-27 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator HE999704.1.gene1528. Protein 2e-26 41
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator HE999704.1.gene2815. Protein 4e-31 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator VFG1563 Protein 4e-27 42
Hprae_0321 YP_005835637.1 winged helix family two component transcriptional regulator VFG1702 Protein 1e-27 42