Gene Information

Name : Hprae_0254 (Hprae_0254)
Accession : YP_005835571.1
Strain : Halanaerobium praevalens DSM 2228
Genome accession: NC_017455
Putative virulence/resistance : Virulence
Product : 3-deoxy-D-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.38
Position : 300358 - 301101 bp
Length : 744 bp
Strand : +
Note : COGs: COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; InterPro IPR003329:IPR004528; KEGG: hor:Hore_18930 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase; PRIAM: 3-deoxy-manno-octulosonate cytidylyltrans

DNA sequence : 
ATGAATAAACTAAAAACAGCTGCTTTGATTCCGGCTCGCTATAATTCTACTCGCTTCCCAGCTAAAGCCCTAGCTAAAAT
TTCAGGGCAAGCAATGATTGTTAGAGTTTATGAGTCAGTAAAAGCCTGTCAGTTAATAGATCAAGTTTATGTTGCTACAG
ATGATCAAAGAATAAAAAAAGCTGTAGAAAAAGCTGGTGGTCAGGTTATTATGACAGATGCTAAACATCAAAGTGGAACA
GATAGAATTGCCGAGGCTGCTGCAGAAATTGAAGCTGATTTAATAGTTAATGTTCAGGGAGATGAACCCTTAATTAGAGC
TCAAGATATTGCTCCAGCGCTGGAAGTTTTTGCTCAGAGACCAGAATTGAAAATGAGTACCTTAAAAAGAAAAATAACTG
CAGCAGAAGCAGAGAATCCTGATCTGGTTAAAGTAATTACTGATCAAAATGATTATGCCCTTTACTTTTCGCGGTCACCG
ATTCCCTATTATCGAGCTGAAACAGTTAAAAATAAAAATTATTATCAACATATAGGTCTTTATGTTTATCGCCGTGATTT
TTTGTTAAAATATGCTAAAATGCAGCAGACTGAATTAGAAAAGGCAGAGTCATTAGAACAACTCCGGGCTCTAGAAAACG
GCTATCAAATAAAAGTTATAGAAACAAATGCTAAACTAATCGGAGTTGATCGCAAAGAAGATATTAAATTAGTTGAAAAA
GAACTTGCAGCTAGGCAAAATTAA

Protein sequence : 
MNKLKTAALIPARYNSTRFPAKALAKISGQAMIVRVYESVKACQLIDQVYVATDDQRIKKAVEKAGGQVIMTDAKHQSGT
DRIAEAAAEIEADLIVNVQGDEPLIRAQDIAPALEVFAQRPELKMSTLKRKITAAEAENPDLVKVITDQNDYALYFSRSP
IPYYRAETVKNKNYYQHIGLYVYRRDFLLKYAKMQQTELEKAESLEQLRALENGYQIKVIETNAKLIGVDRKEDIKLVEK
ELAARQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-42 47
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 9e-43 47
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-41 46