Gene Information

Name : Hprae_1575 (Hprae_1575)
Accession : YP_005836862.1
Strain : Halanaerobium praevalens DSM 2228
Genome accession: NC_017455
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1743750 - 1745504 bp
Length : 1755 bp
Strand : -
Note : COGs: COG0469 Pyruvate kinase; InterProIPR018209:IPR015793:IPR015794:IPR008279:IPR 001697; KEGG: hor:Hore_03220 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM:

DNA sequence :
ATGAGAAAAACTAAAATTGTATGTACTTTAGGACCTGCAACAAATGATAAAGAAATAATTAAGAAAGTAGTAGAAGCGGG
AATGAATGTTGCTCGAATGAATTTCTCTCATGGTAATCATCAAGAACACAAGCAGAGAATTGATTTAGTTAAAGAAGTTG
AAAAAGAAACAGGTCAGGCACTTGGTATTATGCTTGATACTAAAGGGCCGGAGATTAGAACTGGAGAAATGAAAGGTGAT
AAGATTGAATTAGAGACAGATTCAAAACTTATTATTTCTCAAACAGATGTTGAAGGTACAAAAGAAAAAATATCTGTTTC
TTATAAAGGCTTAGCTCAAGATATGGAAATTGGAAATAAAATTTTAATAGATGATGGTTTAATTGAACTAGAAGTTGTAG
AAATTAAGGCAGATAATTTAATTACAAAAGTAATTAATGGTGGTGAACTAGGATCTCGTAAGGGAGTAAATTTACCAGGA
GTTAAAGTTAACTTACCTGCTTTAACTGAAAAAGATATTTCAGATATTAGATTTGGTGTTGAACAGGGGATTCATTTTAT
TGCTGCTTCTTTTGTTCGTAAAGCTGATGATGTTATTGAAATTCGTAAAATATTAGAAGAAAGTGGTAATGAAGATATCT
TTATTATTGCTAAAATAGAAAATCAAGAAGGAGTAGAAAATCTTGCTAGTATTTTAGAAGTAGCAGATGGAATTATGGTT
GCTCGCGGAGACTTGGGAGTAGAAATTCCAGCTGAAAAAGTACCTATTGTTCAGAAAAAAATGATTAGAATGTGTAACGA
AGCATCTAAACCAGTTATTACTGCTACTCAAATGTTAGATTCAATGATTAGAAATCCTCGTCCAACAAGAGCTGAAGCTT
CTGATGTAGCTAATGCAATTTTTGATGGAACTGATGCTACTATGTTATCTGGAGAATCAGCAGCTGGAAAATATCCAGTA
GAATCTGTAGAAACTATGGCTCAAATTGCAAATGAAGTAGAAAATTCTGAAGGTTATAAAGAAAAATTTGCAGGTAATTA
TGAATTTAAAGCAGAATCAGTTACAGCTGCAATTTCACTTGCAACTTGTCAAACTGCAGAAGAACTTGGAGCAGAAGCAA
TAATAACTTCTACTGGCTCTGGTTTGACTGCCCGCACAGTGTCTAAATTTAGACCCCAAACTCCAATAATTGCTGTAACA
CCTAATCAAAGAGTTTTACATCAATTAACAATGACCTGGGGAGTATCTACTTTACTTGCAGCTAGAAGTAATACAACTGA
TGAAATGATGGAAAATGCTATTTCAACAGCTTTAGACTATAATCTTGTTGAAGAAGGAGATTTAGTTACAATTACAGCTG
GAACCCCAGTTGGTATTTCTGGTACTACTAATTTAATTAAAGTAGATGTGGTTGGAAAACCAATTGCTGAAGGTCAGGGA
ATTGGTAAAGGTATTGTAATTGGAAAAGCTAAATTTGTCAAAGATGCAGCAGAAGCTGAAGAAATTATTGAAAAAGGAGA
TATTATAATTACTTCTATGACTGATCGAGACTTTATTCCTGCAATGAAAAAGGCAGCTGCAGTTGTTACTTTTGGTGGGG
GCTTAACTTCCCATCCTGCAATAGTTGGACTTAACATTGGAATTCCAGTGGTAGTTAATACCGGTGATATCAGTGATAAT
TTTGAAAATGGAGAGATTATTACTGTTGATGGAGTTAGAGGTTTAGTTTATAGAGGTCATGCAAACTTAAAATAA

Protein sequence :
MRKTKIVCTLGPATNDKEIIKKVVEAGMNVARMNFSHGNHQEHKQRIDLVKEVEKETGQALGIMLDTKGPEIRTGEMKGD
KIELETDSKLIISQTDVEGTKEKISVSYKGLAQDMEIGNKILIDDGLIELEVVEIKADNLITKVINGGELGSRKGVNLPG
VKVNLPALTEKDISDIRFGVEQGIHFIAASFVRKADDVIEIRKILEESGNEDIFIIAKIENQEGVENLASILEVADGIMV
ARGDLGVEIPAEKVPIVQKKMIRMCNEASKPVITATQMLDSMIRNPRPTRAEASDVANAIFDGTDATMLSGESAAGKYPV
ESVETMAQIANEVENSEGYKEKFAGNYEFKAESVTAAISLATCQTAEELGAEAIITSTGSGLTARTVSKFRPQTPIIAVT
PNQRVLHQLTMTWGVSTLLAARSNTTDEMMENAISTALDYNLVEEGDLVTITAGTPVGISGTTNLIKVDVVGKPIAEGQG
IGKGIVIGKAKFVKDAAEAEEIIEKGDIIITSMTDRDFIPAMKKAAAVVTFGGGLTSHPAIVGLNIGIPVVVNTGDISDN
FENGEIITVDGVRGLVYRGHANLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-102 50
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-102 50
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-102 50
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-102 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hprae_1575 YP_005836862.1 pyruvate kinase VFG0479 Protein 4e-103 50