Gene Information

Name : NE061598_08175 (NE061598_08175)
Accession : YP_005831586.1
Strain : Francisella tularensis NE061598
Genome accession: NC_017453
Putative virulence/resistance : Virulence
Product : dTDP-glucose 4,6-dehydratase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1447501 - 1449237 bp
Length : 1737 bp
Strand : -
Note : COG1086 Predicted nucleoside-diphosphate sugar epimerases

DNA sequence :
ATGTCTTTCTACGATAATAGAACGCTTAATTTCGTGGTAATAATAGTTTTAACTATTATTACTGTTAATTGGACTTTCTA
TATTTTCAAGCAAGATGTTAATTTACATTTTTTACTTGCATTAGTTTTGCTGAGATGCTTGTCATCTTTTTTACTACTTA
GAGATTATATGGCTAGTTGGCGTAAGTCGACTCAAAAAACTTTTTTACGTAAGGCTTTTATTAATTTGCCAGTATTTTTC
ATAGTGGCATTATTTTTTTATGGCAAAGTCACTTTTTCGTTGATATTCTCTGAGTTTTTATTTTATGTTTTTTTGATCAG
TTTAAGTGTCTACTTTTATTGGTATTTGATGAACAGAGGATCAGTGGATAAAAGTAAAACTGCGGTTATTTATGGTGCAG
GTGCTGCAGGAACAAAGATTGCTCAAGAACTTGCTTCTGCTGGTTATCGCATCAAATGTTTTGTTGATGACAATGAAACT
TTACAAAAAAGAAGTATTGATAGTAAAAAGGTTCTATCTAAAGCTGAATTAACAAAACTATTGCTATCTAGTAGATTTGA
CCTTTTGGTTATTGCATTGCCAAGAAATGCAAACCAAGTAGTCAAAAATATATATAAAGAATTTGAAAAGGATTTTAATC
AGATTAGAATTATGCCGCCTCTTGAGGAAATTCTTCAAGATGAGAATTTTATGTCACAGTTGAAGCCTGTTTCACTCTAT
GATCTATTAGCGCGTGATACTAAGAGTTTAGATAAAGAATCTATCTCTAATTTTATCAAAAATAAGGTGGTGCTAGTCAC
AGGAGCTGGAGGTAGTATAGGTTCTGAAATAGTACATCAATGTATCAAGTATCAGGCAAAAGAGTTGATATTGGTTGATC
ATAGTGAGTTTAACTTATATAAAATTACTGAGGAGTGTAGTCATTTTAATATCAATAGTGTGCTATGTTCTGTTTGTGAT
AGAAAAGCATTGGCTGAGGTTTTTCAAAAGTATACTCCAAATATAGTATTTCATGCTGCTGCCTACAAGCATGTTCCCTT
AGTTGAGGAGAATATCTCTAGAGCAATTAGAAATAATATCTTAGGTACTAAGAATGCTATAGATCTGGCTATAGAAGCTG
GTGTTGAGTCATTTATATTGATTTCCACTGATAAAGCAGTGCGACCAACGAATGTTATGGGGGCTACCAAGAGAGTTTGT
GAGCTGTATTTACAGAATGTTGATCCCAAAAATACCAAGCTTGCTGCAGTGCGTTTTGGTAATGTGCTTGGTAGTAGTGG
CAGTGTGATTCCAAAATTTGAAGAGCAAATAAGAAAAGGTGGTCCTGTTACAGTTACTCATCCTGAAATTACACGTTATT
TTATGTTGATACCAGAAGCTTGTGAACTGGTCCTACAAGCTGGTGCTATTGCAAAAAATTCAGAGGTCTTTGTCTTAGAT
ATGGGGCAACCTGTCAAGATTATTGATCTTGCTAAACAATTTATTAGACTTTCTGGTAGAGGTGATATTGATATTAAAAT
AGTTGGTTTGCGTCCAGGAGAGAAACTTTACGAAGAGCTTTTGATAGAGGAAGATGATGTTAGTACCGACTATAAAGATA
TTTTTATTGGTAGAAGGACTTTTTACGATATTAATACTCTAAACCAAGATATTGAATCGTTGATCAAGGATGATGTTGAT
CAGCTTGTGATATTAAAGAAAATTGTTCCGGAATTTGAACATAGATTGAATGGGTAG

Protein sequence :
MSFYDNRTLNFVVIIVLTIITVNWTFYIFKQDVNLHFLLALVLLRCLSSFLLLRDYMASWRKSTQKTFLRKAFINLPVFF
IVALFFYGKVTFSLIFSEFLFYVFLISLSVYFYWYLMNRGSVDKSKTAVIYGAGAAGTKIAQELASAGYRIKCFVDDNET
LQKRSIDSKKVLSKAELTKLLLSSRFDLLVIALPRNANQVVKNIYKEFEKDFNQIRIMPPLEEILQDENFMSQLKPVSLY
DLLARDTKSLDKESISNFIKNKVVLVTGAGGSIGSEIVHQCIKYQAKELILVDHSEFNLYKITEECSHFNINSVLCSVCD
RKALAEVFQKYTPNIVFHAAAYKHVPLVEENISRAIRNNILGTKNAIDLAIEAGVESFILISTDKAVRPTNVMGATKRVC
ELYLQNVDPKNTKLAAVRFGNVLGSSGSVIPKFEEQIRKGGPVTVTHPEITRYFMLIPEACELVLQAGAIAKNSEVFVLD
MGQPVKIIDLAKQFIRLSGRGDIDIKIVGLRPGEKLYEELLIEEDDVSTDYKDIFIGRRTFYDINTLNQDIESLIKDDVD
QLVILKKIVPEFEHRLNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-75 44
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 1e-70 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NE061598_08175 YP_005831586.1 dTDP-glucose 4,6-dehydratase VFG1300 Protein 2e-74 42