Gene Information

Name : guaA (NE061598_05845)
Accession : YP_005831179.1
Strain : Francisella tularensis NE061598
Genome accession: NC_017453
Putative virulence/resistance : Unknown
Product : bifunctional GMP synthase/glutamine amidotransferase protein
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1028706 - 1030256 bp
Length : 1551 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGACAGATATACATAATCATAAGATTTTGATTTTAGATTTTGGCTCGCAATATACACAACTTATTGCTCGTAGAGTAAG
AGAAGTAGGTGTTTTTTGTGAAATTTTCCCTCATGATGTAGCAGCTGATTTTATCAAAAATTATCAAGCAAAAGGAATAA
TTTTATCAGGTGGTCCTGAGTCAGTTTATGATTCTGATGTCAAAGCTCCTGAGATAGTTTTTGAGCTTGGAGTACCTGTT
TTGGGTATTTGTTATGGCATGCAAACAATGGTAATGCAGCATGGTGGCGAAGTAAAAGGAGCTGATCAAAGTGAATTTGG
TAAGGCAATTATAAATATCCTAAATTCAACAAATAACATATTTTCAAATATGGAGCATGAGCAGCTAGTTTGGATGAGTC
ATAGTGACAAAGTCACTCAAACTGGTGAGCATTTTGAGATAATTGCTTCTTCAACAAATGCTCCAGTTGCGGCAGTTGCA
CATAAAAATAAGCCTTTTTTTGGTGTGCAGTTTCACCCAGAAACTACTCATACAGAAAATGGTAAGCAAATTATTGAGAA
TTTTGTCGTTAATATCTGCGGATGTGATACTCTGTGGAATATCGAAAACATTATCGAAAATGATATAAAAGAAATTAAAC
AAAAAGTTGGTACTGATAAAGTAATTTTAGGGCTATCTGGAGGTGTTGATTCATCTGTTGTAGCTGCGATATTACATCAA
GCTATCGGCGATCAGCTAACTTGTATATTTGTAGATACTGGTTTACTGCGCCTTAATGAGGGTGATCAAGTTATGCAAGT
ATTTGCAGAGCATATGGATATTAATGTTATTCGTATCAATGCAAAAAATAGATTCTTAGATGCCCTAAGGGGTATCTGTG
ATCCAGAACAAAAACGTAAAATTATCGGTAAGCTATTTGTTGATATTTTTGATGAAGAGGCTGCTAAGATAGAGAATGCT
AAATGGCTTGCGCAGGGCACTATCTACAGTGATGTAATTGAATCAGCTGGCAATAATCAGTCTAAAGCGCATGTAATTAA
ATCACATCATAATGTTGGTGGCTTACCAAAAGAAATGAAACTTAAGCTTTTAGAACCATTAAGAGAGCTTTTCAAAGATG
AGGTTCGTAAATTAGGCTTAGGTTTAGGATTACCTTATAATATGCTTTATAGACATCCATTTCCTGGTCCTGGTCTTGGA
GTACGTATATTAGGTGAAATAAAGAAAGAGTATGTAGAAACGTTACAAAAAGCTGATGCTATATTTACAGAAGAGCTCTA
TAAACATAATTTATACCATGATGTTTCTCAAGCTTTTGGGGTGTTTTTACCTGTCAAATCGGTAGGTGTAGTTGGTGATC
AGCGTAGATATGAGTATGTAATAGCTCTAAGAGCTGTCGTTAGTATCGATTTTATGACTGCAACGTGGGCTAATTTACCT
TATGATTTTCTGTCACTAGTTTCAAATAGAATTGTAAATGAAGTAAAACAAGTATCAAGAGTTGTGTATGATGTGACAGG
AAAACCACCTGGAACAATTGAATGGGAATAA

Protein sequence :
MTDIHNHKILILDFGSQYTQLIARRVREVGVFCEIFPHDVAADFIKNYQAKGIILSGGPESVYDSDVKAPEIVFELGVPV
LGICYGMQTMVMQHGGEVKGADQSEFGKAIINILNSTNNIFSNMEHEQLVWMSHSDKVTQTGEHFEIIASSTNAPVAAVA
HKNKPFFGVQFHPETTHTENGKQIIENFVVNICGCDTLWNIENIIENDIKEIKQKVGTDKVILGLSGGVDSSVVAAILHQ
AIGDQLTCIFVDTGLLRLNEGDQVMQVFAEHMDINVIRINAKNRFLDALRGICDPEQKRKIIGKLFVDIFDEEAAKIENA
KWLAQGTIYSDVIESAGNNQSKAHVIKSHHNVGGLPKEMKLKLLEPLRELFKDEVRKLGLGLGLPYNMLYRHPFPGPGLG
VRILGEIKKEYVETLQKADAIFTEELYKHNLYHDVSQAFGVFLPVKSVGVVGDQRRYEYVIALRAVVSIDFMTATWANLP
YDFLSLVSNRIVNEVKQVSRVVYDVTGKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-122 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-122 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-122 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-99 46