Gene Information

Name : hsdM2 (R2846_0540)
Accession : YP_005829021.1
Strain : Haemophilus influenzae R2846
Genome accession: NC_017452
Putative virulence/resistance : Virulence
Product : type I restriction modification system, methylase component HsdM2
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 543760 - 546132 bp
Length : 2373 bp
Strand : -
Note : -

DNA sequence :
ATGGAGCATTCTGTTCATAACAAACTGGTTTCTTTTATTTGGAGTATTGCAGACGATTGTCTGCGCGATGTGTATGTGCG
CGGTAAATATCGTGATGTGATCTTGCCGATGTTTGTGCTTCGTCGTTTGGACACCTTGCTTGAGCCAAGCAAAGATGCCG
TATTGGAAGAAATGCGTTTTCAAAAAGAAGAATTGGCATTCACCGAATTGGATGACCTTCCCCTCAAAAAAATTACCGGC
TATGTTTTTTATAACACCTCGAAATGGACATTAAAATCCCTCTATCAAACCGCCGGCAATACGCCGCAGCATATGCTGGC
GAATTTTGAAGAATATCTTGACGGTTTCAGCACCAACGTGCAGGAAATCATCAAATGCTTCAAGCTGAGCGAACAAATCC
GCCATATGTCTCATAAAAATGTTTTGCTGAGTGTGTTGGAAAAATTTGTATCGCCCTATATCAATCTTACCCCTAAAGAA
CAACAAGACCCTGAGGACAACAAATTACCAGCGCTGACCAATCTGGGCATGGGCTATGTATTTGAAGAGCTGATTCGTAA
ATTTAACGAAGAAAACAACGAAGAAGCTGGCGAACACTTTACCCCGCGCGAAGTGATCGAGCTGATGACGCATTTAGTCT
TTGATCCGCTCAAAGACCAAATTCCGGCCATTATTACGATTTACGACCCAGCTTGCGGCAGCGGTGGCATGCTGACCGAG
TCGCAAAACTTTATTGAGCAAAAATATCCGCTATCTGAATCACAAGGCGAGCGTTCCATCTTTTTGTTTGGTAAAGAAAC
CAATGATGAAACCTATGCCATTTGTAAATCTGACATGATGATTAAAGGTGATAATCCCGAAAACATCAAAGTCGGCTCAA
CCCTTGCTACAGATAGCTTCCAAGGTAATCACTTTGACTTTATGCTTTCCAACCCGCCATATGGCAAAAGCTGGAGCAAA
GATCAAGCCTATATCAAAGACGGCAATGAGGTTATCGACAGTCGCTTTAAAGTTACCTTACCAGATTACTGGGGCAATGT
AGAAACCCTTGATGCCACCCCGCGCTCCAGCGATGGTCAGCTGCTTTTCCTGATGGAAATGGTCAACAAAATGAAATCGC
CGAAAAACAACAAAATCGGCAGCCGTGTTGCCTCTGTGCATAACGGCTCAAGCCTGTTTACCGGCGATGCAGGTTCAGGA
GAAAGCAACATTCGTCGCCATATTATTGAAAAAGATTTGCTCGAAGCCATCGTACAGCTGCCTAATAATCTGTTTTATAA
CACAGGCATTACCACTTATATTTGGTTGCTGTCCAACAACAAACCCGAAGCACGCAAAGGCAAAGTTCAGCTCATTGATG
CCGGCCTCTTGTTCCGTAAATTGCGTAAAAACCTCGGCGATAAAAACTGCGAATTTGCACCTGAACATATCGCCGAAATT
ACCCAAAACTATCTTGATTTCACTGCCAAAGCGCGCGAAACCGACAGCCAAAATGAAGCGGTCGGCCTGGCTTCGCAGAT
TTTTGACAATCAAGATTTCGGCTATTACAAAGTCACCATCGAACGCCCGGATCGCCGTTCTGCCCAATTTACCGCCGAAA
ATATCGCGCCTTTACGGTTTGACAAGGCTTTGTTTGAGCCGATGCAATATCTTTATCAGCAACATGGCGAACAAGTTTAC
AACGCAGAATATTTGGCCAAAACCGAGCCAGAAATCAGCACTTGGTGTGAGGCGCAAGGCATTGCCTTAAACAACAAAAA
CAAGGCAAAGCTGCTGGATGTCAAAACGTGGGAAAAAGCTGCCACACTTTTTCAGACGGCCTCAACCTTGCTCGAACATT
TCGGCTCAACCCAATTTGACGATTTCAACCAATTCAAACAAGCAGTGGAAGGCCGTCTGAAAACCGAAAAAATCCCCCTT
TCTGCCACAGAGAAAAAGGCCATTTTCAATGCCGTAAGCTGGTACAACGAAAATGCCGCTAAAGTGATTGCCAAAACACT
CAAGCTCAAACCAAACGAATTGGATGCTCTTTGCCAACGCTACCAATGCCAAGCCGACGAGCTAGCAGACTTTGGCTATT
ACGCCACCGGCAAAGCAGGCGAATATATCCAATATGAAACCAGCAGCGACTTGCGCGACAGCGAATCCATACCGCTCAAA
CAAAATATCCTCGATTATTTCAAAGCCGAAGTGCAACCGCACATCAGCGAAGCATGGCTGAATATGGAAAACGTGAAAAT
CGGCTATGAAATCAGCTTCAACAAATACTTCTACCGCCACAAACCATTACGCAGCCTTGCAGAAGTTGCCCAAGATATTT
TGGCGTTGGAAAAACAGGCTGACGGCTTGATTAGTGAGATTCTAGAGGCTTAA

Protein sequence :
MEHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMFVLRRLDTLLEPSKDAVLEEMRFQKEELAFTELDDLPLKKITG
YVFYNTSKWTLKSLYQTAGNTPQHMLANFEEYLDGFSTNVQEIIKCFKLSEQIRHMSHKNVLLSVLEKFVSPYINLTPKE
QQDPEDNKLPALTNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIELMTHLVFDPLKDQIPAIITIYDPACGSGGMLTE
SQNFIEQKYPLSESQGERSIFLFGKETNDETYAICKSDMMIKGDNPENIKVGSTLATDSFQGNHFDFMLSNPPYGKSWSK
DQAYIKDGNEVIDSRFKVTLPDYWGNVETLDATPRSSDGQLLFLMEMVNKMKSPKNNKIGSRVASVHNGSSLFTGDAGSG
ESNIRRHIIEKDLLEAIVQLPNNLFYNTGITTYIWLLSNNKPEARKGKVQLIDAGLLFRKLRKNLGDKNCEFAPEHIAEI
TQNYLDFTAKARETDSQNEAVGLASQIFDNQDFGYYKVTIERPDRRSAQFTAENIAPLRFDKALFEPMQYLYQQHGEQVY
NAEYLAKTEPEISTWCEAQGIALNNKNKAKLLDVKTWEKAATLFQTASTLLEHFGSTQFDDFNQFKQAVEGRLKTEKIPL
SATEKKAIFNAVSWYNENAAKVIAKTLKLKPNELDALCQRYQCQADELADFGYYATGKAGEYIQYETSSDLRDSESIPLK
QNILDYFKAEVQPHISEAWLNMENVKIGYEISFNKYFYRHKPLRSLAEVAQDILALEKQADGLISEILEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1367 YP_001217310.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 70
VPI2_0017c ACA01834.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 70
VC1769 NP_231404.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 70

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hsdM2 YP_005829021.1 type I restriction modification system, methylase component HsdM2 VFG1102 Protein 0.0 70