Gene Information

Name : topB (R2846_0136)
Accession : YP_005828655.1
Strain : Haemophilus influenzae R2846
Genome accession: NC_017452
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : 5.99.1.2
Position : 134781 - 136736 bp
Length : 1956 bp
Strand : -
Note : -

DNA sequence :
ATGCGTTTATTTATCGCCGAAAAACCAAGCCTAGCTCGTGCTATTGCTGACGTACTCCCCAAGCCCCATCAACGTGGGGA
TGGTTTTATTAAATGTGGCGATAATGATGTGGTAACTTGGTGTGTAGGGCATTTGCTCGAGCAAGCGGAACCCGATGTCT
ATGATCCTAAATTCAAACAATGGCGTTTAGAACATCTCCCTATCATTCCTGAAAAATGGCAACTTTTACCGCGAAAAGAA
GTTAAAAAACAACTTTCTGTGGTAGAAAAACTAATCCATCAAGCTGATACACTCGTTAATGCAGGAGACCCTGATAGAGA
AGGACAATTACTTGTAGATGAAGTGTTCAGTTATGCCAATTTATCTGCCGAAAAACGCGATAAAATTTTACGCTGCTTGA
TTAGCGACCTAAATCCAAGTGCGGTAGAAAAAGCGGTTAAAAAATTACAACCCAACCGTAATTTTATTCCTCTTGCCACA
TCCGCTCTCGCACGAGCTCGCGCCGATTGGCTTTATGGCATTAATATGACCAGAGCCTATACCATTCGTGGCAGACAAAC
TGGCTATGATGGAGTGCTTTCGGTTGGACGAGTGCAAACCCCTGTGCTAGGTTTAATTGTACGTCGAGATTTAGAAATTG
AGCATTTCCAGCCCAAAGATTTCTTTGAAGTACAGGCTTGGGTTAATCCAGAGAGCAAAGAAGAAAAAACTCCAGAAAAA
TCAACCGCACTTTTCAGTGCCTTATGGCAACCTAGCAAAGCTTGCGAGGATTACCAAGATGATGACGGCAGGGTGCTCTC
TAAAGGATTAGCAGAAAACGTTGTAAAACGTATTACAAATCAACCTGCAGAAGTCACCGAATACAAAGACGTTCGTGAAA
AAGAAACGGCGCCCTTGCCTTATTCACTTTCTGCGTTACAAATTGATGCAGCAAAGCGATTTGGTATGTCCGCTCAAGCC
GTATTAGATACGTGCCAACGCCTATATGAAACTCATCGTTTGATTACTTATCCGCGTTCTGATTGTCGCTATTTGCCCGA
AGAACATTTTGCCGAACGACACAATGTATTAAATGCAATTTCAACCCATTGTGAAGCTTATCAACGCTTACCAAATGTCA
TTTCAACTGAACAGAGAAATCGCTGTTGGAATGATAAAAAAGTAGAAGCTCACCATGCAATCATTCCGACTGCCAAAAAT
CGTCCAATACATCTAACACAAGAAGAACGAAATATTTACAGCCTTATCGCTCGCCAATATTTAATGCAATTTTGTCCTGA
CGCAGAATATCGTAAAAGTAAAATCACATTAAATATCGCTGGCGGTACTTTTATAGCTCAAGCGCGAAATTTACAAACGG
CTGGGTGGAAAGAATTATTAGGCAAAGAAGACGACACAGAAAATCAAGAACCCTTATTACCAATAGTAAAGAAAGGACAA
ATTTTGCATTGTGAACGCGGAGAAGTGATGAGTAAAAAAACTCAGCCGCCAAAGCCTTTCACGGATGCAACCTTGCTTTC
AGCAATGACGGGCATTGCACGATTTGTGCAGGATAAAGAACTCAAAAAAATCCTGCGAGAAACCGATGGATTGGGTACAG
AGGCTACTCGCGCTGGCATCATTGAATTACTTTTTAAACGCGGTTTTTTAACAAAAAAAGGGCGAAATATTCACAGTACA
GAAACTGGAAGAATTTTAATTCAAGCGTTACCAGATATTGCCACCCAACCAGATATGACAGCTCATTGGGAATCGCAACT
CACAGACATTAGTCAAAAACAAGCAACCTATCAACAATTTATGCATAACTTGAATCAAATGTTGCCTGATTTAGTCCGTT
TTGTAGATCTTAATGCATTAAGACAATTAAGCCGCATTAAAATGATTAAATCCGATAGGGCGAAACCTAAAAGTGCGGTA
AAAAAATCGAGTAAATCAAACGGTCAAACTGATTAA

Protein sequence :
MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGDNDVVTWCVGHLLEQAEPDVYDPKFKQWRLEHLPIIPEKWQLLPRKE
VKKQLSVVEKLIHQADTLVNAGDPDREGQLLVDEVFSYANLSAEKRDKILRCLISDLNPSAVEKAVKKLQPNRNFIPLAT
SALARARADWLYGINMTRAYTIRGRQTGYDGVLSVGRVQTPVLGLIVRRDLEIEHFQPKDFFEVQAWVNPESKEEKTPEK
STALFSALWQPSKACEDYQDDDGRVLSKGLAENVVKRITNQPAEVTEYKDVREKETAPLPYSLSALQIDAAKRFGMSAQA
VLDTCQRLYETHRLITYPRSDCRYLPEEHFAERHNVLNAISTHCEAYQRLPNVISTEQRNRCWNDKKVEAHHAIIPTAKN
RPIHLTQEERNIYSLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQTAGWKELLGKEDDTENQEPLLPIVKKGQ
ILHCERGEVMSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLTKKGRNIHST
ETGRILIQALPDIATQPDMTAHWESQLTDISQKQATYQQFMHNLNQMLPDLVRFVDLNALRQLSRIKMIKSDRAKPKSAV
KKSSKSNGQTD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 1e-111 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 1e-111 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 1e-111 41