Gene Information

Name : pykA (R2846_1049)
Accession : YP_005829502.1
Strain : Haemophilus influenzae R2846
Genome accession: NC_017452
Putative virulence/resistance : Virulence
Product : Pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1093063 - 1094499 bp
Length : 1437 bp
Strand : +
Note : -

DNA sequence :
ATGTCTAGAAGACTAAGAAGAACGAAGATTGTATGTACTATGGGCCCATCAACTGACCGTGATAACAATCTTGAAAAAAT
TATCGCAGCGGGCGCAAACGTAGTTCGTATGAACTTCTCTCACGGTACACCTGATGACCATATCGGACGTGCTGAACGTG
TACGTTCTATTGCGAAAAAATTAGGTAAAACCGTGGCAATCTTAGGTGATTTACAAGGTCCTAAAATTCGTGTTTCTACT
TTTAAAGACGGTAAAATTTTCTTAAACGTTGGCGATAAATTCATTCTTGATGCAGAGTTACCAAAAGGCGAAGGCACTCA
AGAATCCGTTGGTTTAGACTATAAAACGCTTCCTCAAGATGTTGTGCCTGGCGATATTCTTTTATTAGATGATGGCCGTG
TTCAATTAAAAGTATTATCAACTGATGGTGCAAAAGTTTTCACTGAAGTTACTGTTGGTGGTCCATTATCAAATAATAAA
GGTATCAATAAATTAGGTGGCGGTTTATCTGCGGATGCCCTAACAGAAAAAGATAAAGCCGACATTATTACCGCTGCACG
CATTGGTGTTGATTTCTTAGCCGTTTCTTTCCCTCGTTCAAGTGCAGATTTAAATTATGCACGTGAACTTGCTCAACAAG
CAGGTTTAAATGCAAAAATCGTTGCTAAAGTTGAACGTGCAGAAACCGTTGCTAATGATGAAGCCATGGACGATATTATT
TTAGCATCTGATGTAATTATGGTTGCTCGTGGTGACTTAGGCGTAGAAATCGGCGATCCTGAATTAGTCGGTGTACAGAA
AAAATTAATTCGTCGTTCACGTCAATTAAATCGTGCTGTAATTACAGCGACTCAAATGATGGAATCAATGATTAGTAACC
CAATGCCAACGCGTGCTGAAGTAATGGACGTTGCAAACGCAGTATTAGATGGAACTGATGCAGTTATGCTTTCTGCAGAA
ACAGCAGCAGGTCAATATCCTTCTGAAACAGTGGCAGCAATGGCTAGCGTATGTTTAGGTGCAGAAAAAATGCCAAGCAT
TAACGTTTCTCGTCACCGTATGGATAAAGAATTTGAAACCATTGAAGAATCTGTTGCGATGTCTGCAATGTATGCAGCAA
ACCACATGAAAGGTGTAGCGGCAATCGTCACTTTAACTAGCACAGGCCGTACTCCATTATTAATGTCACGCATTAGCTCT
GGCTTACCAATCTTTGCTTTATCTCGTAATCAAGAAACCCTAAACCTTTGTGCACTATACCGCGGTGTAACACCAATTTA
TCACGGTGAAGAAAGTCGTACAGAAGCAGGTGCAAAAGCAGCACTTCAATCATTAAAAGAAAAAGGTTATTTATCTACTG
GCGATTTAGTACTGGTAACCCAAGGTGGTCAAGGTGCGACACAAACTAACGTATGTCGTACATTAATTGTTGAATAA

Protein sequence :
MSRRLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVST
FKDGKIFLNVGDKFILDAELPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNK
GINKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANDEAMDDII
LASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAE
TAAGQYPSETVAAMASVCLGAEKMPSINVSRHRMDKEFETIEESVAMSAMYAANHMKGVAAIVTLTSTGRTPLLMSRISS
GLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQGGQGATQTNVCRTLIVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 9e-78 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-55 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-55 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-56 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_005829502.1 Pyruvate kinase VFG0479 Protein 1e-55 41