Gene Information

Name : FN3523_1394 (FN3523_1394)
Accession : YP_005824448.1
Strain : Francisella novicida 3523
Genome accession: NC_017449
Putative virulence/resistance : Virulence
Product : Pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1436090 - 1437526 bp
Length : 1437 bp
Strand : -
Note : -

DNA sequence : 
ATGAGAAGAACAAAAATTTTAGCTACTCTTGGTCCTGCTAGTGAATCAAGAGAAGCTCTAACAGAGATGATTAAAGCAGG
CGTCAATGCGGTTAGATGTAATTTTTCGCATGGATCTGCTGAGGATCATCGTAAAAGAGTTGATTTAATTCGTCAAATCG
CAAAAGAGCAAGATACACATGTTGGTATTTTAGCTGATTTACAGGGACCAAAAATCAGATTATCAAAATTTAAAAATGGT
TCCGTAGAAATTAAGAAAGGTCAAAAATTTACACTGGATGCTGATCTTGGAGTTAATGATGGTGATGAGAATACTGTAGG
AATTGACTATAAAGAACTGATCCAAGATGTAAAAAAAGGTGATATATTACTTGTAGATGATGGCAAAATTGTCTTAGAGG
TTGATTCTGTAAAAGGAAATAAAGCAGTCACTAAAGTTGTCGTTGGTGGCAAAGTTTCTAATAATAAGGGTATCAATAAA
AAAGGTGGTGGGCTGACAGCGCCTGCACTTACTGAGAAAGACAAAGAAGATATAAAAATAGCGGCAATGCTGCAAGTCGA
TTTCTTAGCGGTATCATTCGTCAGGGATGGTAAGGATATGGAGTATGCACGCCAACTTGTCCATGAAGCTGGCTGGAGAC
CTGCTATGGTTGCTAAAATTGAGCGTGCAGAGGCTGTATTAGAAGATAATCTTAAGAGTATTGTTGATGCTTCTGACCTT
GTAATGGTAGCACGTGGTGATTTGGCTGTTGAAATCGGTGATGAAAATGTGCCAACTGTACAGAAGCTTATTATTAGTAC
AGCTAGAAGAAATGAAAAAGGTTCTATTACTGCTACACAGATGATGGAGTCAATGATAGAGAACTCTTCACCAACTCGTG
CAGAGGCATCTGATGTTGCTAATGCTGTGTTTGATGGTACAGATGCTGTGATGTTATCAGCTGAAACTGCGGTAGGTAAA
TATCCTGTTGAAACAGTTTCTGCAATGTCAAGAATATGTAAATCAGCTGAGAAAAGTAGGTATACACATATTTCTAAAAA
GCAAAAAATAGCTGATTGTGATAGGATTGATCATGCTGTTTCTGTTGCAGCAGTCAAAATAGCTAACGATATCGGTGCTA
AAGGATTAATCGTATTAACAGAAGGTGGCAATACTTCGCGTTGGATGTCACGAATAAATACTGATTTACCTATTTATGCA
TTATCACGAAATGCTACAACTTTAGGTGCAATGACATTATTTAGAGGAGTCGTGCCAATATATTTTGATTCAACTAGAAT
GTCTAAGTTGTATGTAAATAGATCAGCTTGTATGGAGCTAGAGAGCAGAAATTTAGCTAAAGATGGTGATATTTTTGTGC
TTACTAGTGGTGATAGTATGGGTGTTCATGGAAGCACTAATAAGATTAAAGTAATAATTGCAGGTCAGGTAAGATAA

Protein sequence : 
MRRTKILATLGPASESREALTEMIKAGVNAVRCNFSHGSAEDHRKRVDLIRQIAKEQDTHVGILADLQGPKIRLSKFKNG
SVEIKKGQKFTLDADLGVNDGDENTVGIDYKELIQDVKKGDILLVDDGKIVLEVDSVKGNKAVTKVVVGGKVSNNKGINK
KGGGLTAPALTEKDKEDIKIAAMLQVDFLAVSFVRDGKDMEYARQLVHEAGWRPAMVAKIERAEAVLEDNLKSIVDASDL
VMVARGDLAVEIGDENVPTVQKLIISTARRNEKGSITATQMMESMIENSSPTRAEASDVANAVFDGTDAVMLSAETAVGK
YPVETVSAMSRICKSAEKSRYTHISKKQKIADCDRIDHAVSVAAVKIANDIGAKGLIVLTEGGNTSRWMSRINTDLPIYA
LSRNATTLGAMTLFRGVVPIYFDSTRMSKLYVNRSACMELESRNLAKDGDIFVLTSGDSMGVHGSTNKIKVIIAGQVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-74 47
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-56 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-56 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-56 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-56 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
FN3523_1394 YP_005824448.1 Pyruvate kinase VFG0479 Protein 7e-57 41