Gene Information

Name : G11074_01705 (G11074_01705)
Accession : YP_005815053.1
Strain : Chlamydia trachomatis G/11074
Genome accession: NC_017440
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 374830 - 376287 bp
Length : 1458 bp
Strand : +
Note : COG0469 Pyruvate kinase

DNA sequence :
ATGGTCGCTAGAACGAAAATTATTTGTACGATAGGCCCTGCAACGAATACCCCTGAGATGCTGGAAAAGCTTCTTGATGC
AGGGATGAATGTAGCTCGCCTTAATTTTAGCCACGGGACCCATGAAAGCCATGGCCGGACCATCGCTATTCTTAAAGAAC
TACGAGAGAAGCGCCAAGTTCCTTTAGCTATTATGCTAGATACAAAAGGTCCCGAAATTCGTTTAGGCCAAGTAGAATCT
CCTATAAAAGTACAGCCTGGGGATCGTCTTACTCTCGTTAGCAAAGAAATTTTAGGATCCAAAGAAAGCGGCGTTACTCT
TTATCCAAGTTGTGTATTCCCTTATGTTAGAGAACGAACTCCTGTTCTCATTGATGATGGGTATATCCAAGCAGTGGTGG
TCAATGCTCAAGAGCATATGGTGGAAATAGAGTTTCAAAATTCAGGAGAAATAAAATCCAACAAATCTCTTAGCATCAAA
GATATCGATGTTGCTCTTCCTTTCATGACAGAGAAGGATATTGCAGACTTAAAATTTGGGGTAGAACAAGAACTCGATCT
TATCGCTGCTTCGTTCGTCAGATGTAATGAAGATATTGACAGCATGCGTAAAGTTTTGGAAAGCTTTGGTCGTCCTAATA
TGCCCATCATTGCTAAAATAGAAAATCATTTAGGAGTACAAAATTTCCAAGAGATCGCTAGAGCTGCTGATGGTATCATG
ATTGCACGCGGGGATCTTGGTATTGAATTGTCTATTGTTGAAGTTCCTGGACTACAAAAATTTATGGCCCGAGCATCGAG
GGAAACGGGTCGGTTTTGTATCACTGCAACGCAAATGCTCGAGTCAATGATTCGCAACCCCCTTCCTACACGAGCCGAAG
TCTCTGACGTTGCCAACGCCATTTACGATGGAACCTCTGCAGTCATGTTGTCTGGAGAAACTGCCTTAGGAGCCCATCCT
GTACATGCAGTAAAAACAATGCGTTCCATTATCCAAGAGACTGAGAAGACTTTCGATTACCACGCTTTTTTCCAGCTGAA
CGACAAAAACAGCGCTCTCAAAGTTTCTCCTTATCTTGAAGCCATTGGGTTTTCTGGAATCCAAATTGCAGAAAAAGCAT
CTGCCAAAGCCATTATTGTGTATACCCAGACGGGAGGATCTCCGATGTTTTTATCCAAATATCGACCTTATCTCCCTATT
ATTGCTGTTACCCCTAACCGCAATGTGTACTATCGTTTAGCTGTAGAATGGGGAGTATATCCTATGCTAACCCTAGAATC
GAACCGTACAGTCTGGCGTCACCAAGCTTGTGTATATGGAGTAGAAAAAGGAATTCTTTCTAACTATGATAAAATTCTTG
TCTTCAGCCGCGGAGCTGGGATGCAAGATACCAACAATCTCACCTTGACAACTGTGCATGATGTGCTATCCCCCTCTCTT
GACGAGATAGTTCCATAA

Protein sequence :
MVARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPLAIMLDTKGPEIRLGQVES
PIKVQPGDRLTLVSKEILGSKESGVTLYPSCVFPYVRERTPVLIDDGYIQAVVVNAQEHMVEIEFQNSGEIKSNKSLSIK
DIDVALPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRPNMPIIAKIENHLGVQNFQEIARAADGIM
IARGDLGIELSIVEVPGLQKFMARASRETGRFCITATQMLESMIRNPLPTRAEVSDVANAIYDGTSAVMLSGETALGAHP
VHAVKTMRSIIQETEKTFDYHAFFQLNDKNSALKVSPYLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPI
IAVTPNRNVYYRLAVEWGVYPMLTLESNRTVWRHQACVYGVEKGILSNYDKILVFSRGAGMQDTNNLTLTTVHDVLSPSL
DEIVP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-63 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-63 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-62 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-63 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
G11074_01705 YP_005815053.1 pyruvate kinase VFG0479 Protein 2e-63 43