Gene Information

Name : mecB (CTDEC_0286)
Accession : YP_005811338.1
Strain : Chlamydia trachomatis D-EC
Genome accession: NC_017434
Putative virulence/resistance : Virulence
Product : Negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 317971 - 320535 bp
Length : 2565 bp
Strand : +
Note : -

DNA sequence :
ATGTTTGAGAAGTTTACCAATCGCGCAAAGCAAGTGATTAAGTTGGCGAAAAAAGAGGCTCAACGACTCAATCACAACTA
TCTAGGAACCGAGCACATCTTGTTAGGATTACTAAAATTAGGCCAGGGTGTGGCTGTTAATGTATTACGCACTCTTGGTG
TTGACTTCGATACAGCAAAGCACGAAGTAGAAAGGCTGATTGGCTATGGCCCCGAGATTCAAGTTTGCGGAGATCCAGCT
CTTACTGGAAGAGTGAAGAAATCTTTTGAATCCGCTAATGAAGAAGCTGCTCTTTTAGAACACAATTATGTTGGAACTGA
ACATCTTTTGTTAGGTATTCTCAATCAATCCGATGGAGTGGCTTTGCAAGTATTAGAAAATTTGCACGTGGATCCTAAAG
AAATCCGAAAAGAGATTTTAAAAGAATTAGAAACATTTAATTTACAACTCCCCCCCTCTTCCTCCATCACTCCTAGAAAT
ACTAATAGCTCTTCTTCTTCGAAATCTTCTTCTCCTTTAGGAGGTCATACTTTGGGCGGAGATAAACCTGAAAAACTTTC
AGCTTTGAAGGCGTACGGTTACGACTTAACAGAAATGTTTAAAGAATCGCGCCTCGATCCAGTGATCGGGCGTTCTGCAG
AAGTCGAACGATTAATTTTAATTCTTTGTCGTCGAAGAAAAAATAACCCAGTCTTAGTTGGAGAAGCTGGAGTAGGGAAA
ACAGCCATTGTAGAAGGCCTCGCTCAGAAAATTGTCTCAGGAGAAGTTCCTGAAGCTCTTCGTAAAAAACGCTTGATCAC
TTTAGATTTGGCTCTAATGATTGCAGGAACCAAATACAGAGGGCAGTTTGAAGAACGCATCAAAGCTGTGATGGATGAAG
TTCGTAAACATGGGAACATCCTCTTATTTATTGATGAGCTTCACACGATTGTTGGTGCAGGAGCTGCTGAAGGAGCTATC
GATGCTTCTCATATTCTAAAACCAGCTCTAGCTCGAGGAGAAATTCAGTGCATTGGCGCTACGACCCTAGATGAATACCG
TAAACATATAGAAAAAGATGCCGCTTTAGAACGTCGGTTCCAAAAAATCGTTGTTCAACCTCCTAGCGTCGATGAAACAG
TAGAAATTCTCAGAGGTTTAAAGAAAAAATACGAAGAGCATCACAATGTCTTCATCACTGATGAAGCACTAGTTGCTGCA
GCTAAACTCTCTGACCAATATGTTCATGGTCGATTTCTTCCTGATAAAGCAATTGACCTCTTGGATGAAGCTGGAGCTCG
TGTACGAGTCAATACGATGGGACAACCTTCGGACCTGGTGCGTCTAGAAGCTGAGATAGAAAAAACAAAACAAGCTAAAG
AGCAAGCTATCGGAACTCAGGAATACGAAAAAGCTGCTAGCCTTCGTGATGAAGAGAAGAAGTTAAGAGAAAAATTAGGA
AATATGAAACAACAGTGGGAGTCCAATAAGGAAGAACATCAAGTTCCCGTTGATGAAGAAGCTGTTGCACAAGTAGTTTC
CGTACAAACAGGAATTCCTGCAGCTCGTTTAACAGAAGCTGAAAGCGAAAAACTTTTAACCTTAGAAACGACTCTACAAA
AGAAAGTAATCGGCCAAAGTCAAGCTGTTGCTAGTATCTGTAGAGCTATCCGTCGTTCTAGAACAGGCATCAAAGATCCT
AATAGACCTATGGGATCCTTCCTATTTTTGGGCCCAACTGGTGTCGGGAAGACTTTATTAGCGCAGCAAATCGCAATTGA
GATGTTTGGAGGAGAAGATTCTCTTATTCAAGTGGACATGTCTGAGTACATGGAAAAATTTGCAGCCACTAAGATGATGG
GATCTCCTCCAGGATATGTCGGTCATGAGGAAGGGGGTCATCTAACAGAGCAAGTCCGTCGCCGCCCTTACTGTGTTGTG
TTGTTTGATGAAATTGAAAAAGCACATCCAGATATTATGGACCTTATGCTTCAGATTTTGGAGCAAGGGCGTTTAACAGA
CTCATTTGGACGTAAGATCGATTTTCGTAATACCATCATCATTATGACTTCTAACCTAGGAGCAGATTTAATTCGGAAAA
GTGGTGAAATAGGGTTTGGGCTTCGTTCTCACATGGACTATGCAGTTATTAAAGAGAAAATAGATGCTGCAGTTAAGAAG
CATTTAAAACCCGAGTTTATCAACCGTTTAGATGAGAGTGTTATCTTTAAGCCTCTTGAAAAAGAAGCTCTTTCAGAGAT
TATCCATCTAGAAATTAATAAGCTGGGCTCTCGTTTACAAAACTATCAAATGGATCTTAATATTCCTGATTCAGTGATTT
CCTTTTTGGTAACTAAAGGGCATTCGCCAGAAATGGGAGCTCGACCTTTAAGACGTGTTGTGGAGCAGTATCTGGAGGAT
CCTTTGGCAGAAATGCTATTGAAAGAGTCTTGCCGACAAGAAGCTAGAAAATTACGCGCGCGCCTCACAGAAGAACGCGT
TGTTTTCGAAAGAGAAGAAGAAGCTGTTTCTGCTTTAGCTATAGAAGGCGATGGCTCAGAGCCTATTACAGCTGATGAAT
CATAG

Protein sequence :
MFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRTLGVDFDTAKHEVERLIGYGPEIQVCGDPA
LTGRVKKSFESANEEAALLEHNYVGTEHLLLGILNQSDGVALQVLENLHVDPKEIRKEILKELETFNLQLPPSSSITPRN
TNSSSSSKSSSPLGGHTLGGDKPEKLSALKAYGYDLTEMFKESRLDPVIGRSAEVERLILILCRRRKNNPVLVGEAGVGK
TAIVEGLAQKIVSGEVPEALRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAI
DASHILKPALARGEIQCIGATTLDEYRKHIEKDAALERRFQKIVVQPPSVDETVEILRGLKKKYEEHHNVFITDEALVAA
AKLSDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPSDLVRLEAEIEKTKQAKEQAIGTQEYEKAASLRDEEKKLREKLG
NMKQQWESNKEEHQVPVDEEAVAQVVSVQTGIPAARLTEAESEKLLTLETTLQKKVIGQSQAVASICRAIRRSRTGIKDP
NRPMGSFLFLGPTGVGKTLLAQQIAIEMFGGEDSLIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVV
LFDEIEKAHPDIMDLMLQILEQGRLTDSFGRKIDFRNTIIIMTSNLGADLIRKSGEIGFGLRSHMDYAVIKEKIDAAVKK
HLKPEFINRLDESVIFKPLEKEALSEIIHLEINKLGSRLQNYQMDLNIPDSVISFLVTKGHSPEMGARPLRRVVEQYLED
PLAEMLLKESCRQEARKLRARLTEERVVFEREEEAVSALAIEGDGSEPITADES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-169 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mecB YP_005811338.1 Negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 51
mecB YP_005811338.1 Negative regulator of genetic competence clpC/mecB VFG0080 Protein 6e-141 50