Gene Information

Name : cadA (EPYR_00935)
Accession : YP_005801686.1
Strain : Erwinia pyrifoliae DSM 12163
Genome accession: NC_017390
Putative virulence/resistance : Virulence
Product : lysine decarboxylase
Function : -
COG functional category : -
COG ID : -
EC number : 4.1.1.18
Position : 1024757 - 1027069 bp
Length : 2313 bp
Strand : +
Note : Lysine decarboxylase (LDC),Ornithine/lysine/arginine decarboxylase

DNA sequence :
ATGTTGGACTTCAATCTGACATTTGCCGGTACGGTTTCCTGTCTGGCCCTTTTTGTTTCGGTGTCCCTGCTGCCCGGTTA
TCCTTATGTTGCTGCCAGACGCCGCGTGTGGATCAGGCAAAACTCTCTGGAGAATGTCATGAATATTATTGCCATCATGG
GCCCGCACCACGTCTTCTACAAAGACGAGCCTGTCCGTGAGCTGGATGTCGCATTAAAACGACAGGGGTTTCACACCGTT
CATCCGCAGGGTGCTGAGGATTTGCTGAAGCTTGTCGAGCACAATCCGCGCATCTGCGGCGTGGTGTTTGACTGGGATGA
GTACAGTCTTGATCTCTGTAGCGAGATCAACCAGCTGAATGAATATTTGCCGCTTTACGCGTTTATCAATACCGATTCGA
CGATGGATGTCGGCGTTAACGAGATGCGCATGGCGATCTGGTTCTTCGAGTATGCGCTCAATGCCGGTGAAGAGATTGCC
CAGCGCATTCGCCAATATACCGATGAATACATTGATACCATCACGCCGCCGCTGACCAAAGCGCTGTTTAACTACGTCAA
AGAGGGAAAGACAACTTTCTGTACGCCAGGGCATATGGCGGGTACGGCATTCCAGAAAAGCCCGGTGGGCAGCCTGTTCT
ATGATTTCTTTGGTGCCAATACGCTGAAGGCGGATATCTCGATTTCGGTTAGCGAATTAGGTTCGTTGCTCGACCACACC
GGCCCCCACCTTGAGGCGGAGGAGTATATAGCGCGCACCTTTGGCGCGGAACAGAGCTATATGGTCACCAATGGCACCTC
CACCGCCAACAAGATTGTCGGTATGTACGCGGCAGCAGCAGGCAGTACCGTGTTGATAGACCGCAACTGCCATAAATCCC
TGACCCATCTGCTGATGATGAGCGATATTATTCCCGTCTGGCTGAAGCCAACGCGCAATGCGCTGGGTATTCTTGGCGGC
ATCCCGAAGCGCGAATTTACCAAAGAGAGCATTGCGCTCAAAGTGGCACAAACGCCGCGCGCCAGCTGGCCGCTACATGC
GGTGATCACGAATTCGACCTATGACGGGCTGCTGTATAACACGCAATACATCAAAGAGACGCTGGAGGTACCGTCGATTC
ACTTCGACTCGGCATGGGTGCCTTACACTAACTTCCACCCGATCTATCGGGGATTGAGCGGTATGAGCGGCGAACGTACG
CCGGGTAAGGTGATTTACGAGACGCAGTCCACACACAAATTGCTGGCCGCGTTTTCTCAGGCTTCGCTGATCCACATTAA
AGGCGACTACGATGAACAGACCTTTAATGAAGCCTATATGATGCATACCACCACTTCGCCGAACTACGCCATCGTCGCCT
CTATCGAAACGGCAGCGGCGATGCTGCGCGGTAATTCAGGCAAACGTCTGATTAACCGCTCGGTAGAGCGTGCGCTGCAT
TTCCGCCGCGAAGTACAGCGGCTGCGTGAAGAGTCAGACGGCTGGTTCTTTGATATCTGGCAGCCGGACGGGGTTGAGGA
GCCGGAATGTTGGGCGATCCAGCCCGGTGACGAGGAGTGGCACGGTTTCCGCGATGCCGATGCCGATCATATGTACCTCG
ACCCGATCAAGGTGACGATCCTGACGCCCGGTATGAGCGAGATGGGCGAGATGGCAGAAGAGGGCATTCCGGCGGCGCTG
GTGGCCAAGTTCCTTGACGAGCGCGGCGTGGTGGTGGAAAAAACCGGGCCGTACAACCTGCTGTTCCTGTTCAGCATCGG
TATTGATAAAACCAAAGCAATGAGCGTATTGCGCGGACTGACGGAGTTCAAACGCGCTTACGATCTCAATCTGCGGGTAA
AAAACATGCTGCCGGATCTGTACGCAGAGGATCCAGACTTCTACCGCAATATGCGTATTCAAACCCTGGCACAGGGCATT
CACAGCCTGATCCGCCAGCACGATTTGCCACGCCTGATGCTGCAAGCCTTCGCCATGCTGCCGGAAATGAAGTTAACGCC
GCACCAGATGTTTCAGCAGCAGGTAAAAGGCAATGTGGAAACGGTTGATATCAGCCAGCTGATTGGGCGCGTGTCGGCCA
ATATGATCCTGCCTTATCCGCCCGGCGTGCCGCTGGTGATGCCGGGGGAAATGATCACTGCGGAGAGTCGTCCGCTGCTC
GATTTCTTACTGATGCTGTGTACCATCGGCAGACATTATCCTGGCTTTGAAACCGATATTCACGGTGCAAAATTGACCGA
AGTGGGGCAATATCTGGTGCGGGTGCTGAAGCACGATGGCGAAGTGCAGGCTGCCGGAAATGCGGTGGTTTAA

Protein sequence :
MLDFNLTFAGTVSCLALFVSVSLLPGYPYVAARRRVWIRQNSLENVMNIIAIMGPHHVFYKDEPVRELDVALKRQGFHTV
HPQGAEDLLKLVEHNPRICGVVFDWDEYSLDLCSEINQLNEYLPLYAFINTDSTMDVGVNEMRMAIWFFEYALNAGEEIA
QRIRQYTDEYIDTITPPLTKALFNYVKEGKTTFCTPGHMAGTAFQKSPVGSLFYDFFGANTLKADISISVSELGSLLDHT
GPHLEAEEYIARTFGAEQSYMVTNGTSTANKIVGMYAAAAGSTVLIDRNCHKSLTHLLMMSDIIPVWLKPTRNALGILGG
IPKREFTKESIALKVAQTPRASWPLHAVITNSTYDGLLYNTQYIKETLEVPSIHFDSAWVPYTNFHPIYRGLSGMSGERT
PGKVIYETQSTHKLLAAFSQASLIHIKGDYDEQTFNEAYMMHTTTSPNYAIVASIETAAAMLRGNSGKRLINRSVERALH
FRREVQRLREESDGWFFDIWQPDGVEEPECWAIQPGDEEWHGFRDADADHMYLDPIKVTILTPGMSEMGEMAEEGIPAAL
VAKFLDERGVVVEKTGPYNLLFLFSIGIDKTKAMSVLRGLTEFKRAYDLNLRVKNMLPDLYAEDPDFYRNMRIQTLAQGI
HSLIRQHDLPRLMLQAFAMLPEMKLTPHQMFQQQVKGNVETVDISQLIGRVSANMILPYPPGVPLVMPGEMITAESRPLL
DFLLMLCTIGRHYPGFETDIHGAKLTEVGQYLVRVLKHDGEVQAAGNAVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 71
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_005801686.1 lysine decarboxylase VFG1670 Protein 0.0 62