Gene Information

Name : hsdM (EPYR_03799)
Accession : YP_005804550.1
Strain : Erwinia pyrifoliae DSM 12163
Genome accession: NC_017390
Putative virulence/resistance : Virulence
Product : type I restriction-modification system DNA methylase
Function : -
COG functional category : -
COG ID : -
EC number : 2.1.1.72
Position : 3848981 - 3851362 bp
Length : 2382 bp
Strand : -
Note : N-6 DNA methylase, N-6 DNA Methylase, hsdM: type I restriction-modification system, M subunit

DNA sequence :
ATGGATCACAGCGTACACAACAAACTGATTTCTTTTATCTGGAACATCGCCGACGACTGCCTGCGTGATGTGTATGTTCG
GGGTAAATATCGTGACGTCATTCTGCCTATGGTGGTACTGCGTCGTCTTGATACCCTGTTAGAGCCGGGCAAAGAGGCCG
TGCTGGCTGAAGTCAAGTTTCAGAAAGAAGAACTACGGGCAACTGAACTGGATGATGCGCCACTCATGGCGGCCAGTGGC
TATGTGTTTTACAACACTTCAAAGTGGACGTTAAATTTGCTGTTCAAGGCGGCGACCAACAACCAGCAGATCCTGTTGGC
GAACTTTGAAGAGTACCTGCTGGGCTTCAGTGACAACGTTAAAGAGATCGTCGCCTGCTTTAACCTGCAGGCACAAATCC
GCCATATGGCGTCGAAGCAGGTGCTGCTGGATGTGGTGGAAAAGTTCGTCTCGCCTTATATCAACCTGACGCATAAAGCC
GTGGAAGACCCCGAAGGCTACACTATGCCAGCCCTGTCAAATTTGGGCATGGGCTACGTCTTTGAAGAGCTTATTCGTAA
ATTTAACGAAGAAAATAACGAAGAGGCCGGGGAGCACTTCACGCCAAGGGAAGTGATCGACCTGATGACGCACCTGGTAT
TTGACCCGGTGAAAGACAAATTGCCGCTAACGATGACGGTATACGATCCGGCCTGCGGTAGCGGCGGTATGCTGACCGAA
TCGCAGAACTTTATCGAAGCAAAATACCCCAGCAGCAATCGTGATATTTACCTGTACGGTAAAGAGATCAACGACGAAAC
CTATGCTATCTGTAAGTCAGATATGATGATCAAAGGCAACAACCCCGAGAACATCCGGGTGGGTTCAACGCTATCGACCG
ATGAATTTGCCGCAGAGCGTTTTGACTTTATGCTGTCAAACCCGCCCTATGGCAAAAGCTGGGCCTCTGAGCAGAAGTAC
ATCAAAGATGGCGGCGATGTGATTGACCCACGCTTTAAGGTCCGGCTGCAGGACTACTCGGGCAAAGAAGAGACGGTGGA
TGCCACGCCGCGCTCCAGTGACGGACAGCTGCTGTTCCTGATGGAAATGGTCAGCAAAATGAAAGACCCGGCGATCGGCT
CGCTGGGCAGTCGCATTGCCTCGGTGCACAACGGATCTTCTCTTTTCACCGGTGATGCCGGCGGTGGTGAAAGTAATATC
CGCCGTTACCTGATTGAAAACGATATGCTGGATGCTATCGTGCAGCTGCCCAATAACCTGTTCTATAACACCGGTATCAC
CACCTATATCTGGCTGCTGAATAATAACAAACCGCAGGATCGCCAGGGCAAGGTGCAGCTGATTGATGCCAGCCTGCTGT
ATCGCAAACTGCGCAAGAACCTCGGCAATAAAAACTGCGAGTTTGCCCCCGAACATATTGCCGAGATCGCGCAAACCTAC
CTCGCTTGTGCCGGGGTGGAAAGAAAACTGGACGCTAACCACGATGCCGTGGGTATTGCCAGCAAGGTATTCAGTAACGA
TGACTTTGGCTATTACAAGGTCACCGTCGAGCGCCCAGACCGGCGTAAGGCCCGCTTTACCCGTGAGGCCATTCAGCCGC
TGCGCTTTGATAAACAGCTTGCCGAGGTGATGGCCTGGCTGTATGGCGAACACGGTGACAAAATCTACGAAAAGGGCTTT
TTAGCCTCGGTCGAAAAAGCCACGCTGGCCTGGTGCGCAGAGCGCGATATCAGTCTGAATACTAAGGCCAAAAGCAAGCT
GCTCGACGTGAAAAACTGGCTGTCGTTGCAGAGGGTGTATCACACCGCTGAACGGCTGATGGCCACCCTCGGCGGCGGCG
AATTTGACGATTTCAACCTGTTCAAAGCGCAGGTTGAACAGGTGCTGAAAGCGGAAAAAATCAAGCTGTCTGCGGCTGAG
AAGAACGCGATTGTAAACGCGGTAAGCTGGTATGACGAGACGGCGGCCAGAGTCATCAATAAAACGGTGAAGCTGAACGG
CGATAAGCTACAGGACCTGTTAGCACGCCTGGAATGTGAAGCGGAAGATCTGCCTGATTTTGGTTTTTACCCCAGCGGCA
AAAAAGACGAATATATTATTTACGACAGCAGTGCAGATCTGCGTGATACGGAATCAGTACCGCTTAAGCAAAGTATTTAC
CAGTATTTCCTCGATGAAGTGAAGCCGCATGTGGCAGAGGCCTGGATTAATCTGGACTCGGTGAAAATTGGCTACGAGAT
CAGCTTTAATAAGTACTTCTATCACCCTAAGCCGTTGCGTTCTCTGGAAGAGGTGGCGCAGGACATTATCAAGCTGGAGC
AGCAGTCTGAAGGCCTGATTGCGCAGATTTTGGGCGTTTCAGTTGACAAGATTCAGGGATAA

Protein sequence :
MDHSVHNKLISFIWNIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPGKEAVLAEVKFQKEELRATELDDAPLMAASG
YVFYNTSKWTLNLLFKAATNNQQILLANFEEYLLGFSDNVKEIVACFNLQAQIRHMASKQVLLDVVEKFVSPYINLTHKA
VEDPEGYTMPALSNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIDLMTHLVFDPVKDKLPLTMTVYDPACGSGGMLTE
SQNFIEAKYPSSNRDIYLYGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFAAERFDFMLSNPPYGKSWASEQKY
IKDGGDVIDPRFKVRLQDYSGKEETVDATPRSSDGQLLFLMEMVSKMKDPAIGSLGSRIASVHNGSSLFTGDAGGGESNI
RRYLIENDMLDAIVQLPNNLFYNTGITTYIWLLNNNKPQDRQGKVQLIDASLLYRKLRKNLGNKNCEFAPEHIAEIAQTY
LACAGVERKLDANHDAVGIASKVFSNDDFGYYKVTVERPDRRKARFTREAIQPLRFDKQLAEVMAWLYGEHGDKIYEKGF
LASVEKATLAWCAERDISLNTKAKSKLLDVKNWLSLQRVYHTAERLMATLGGGEFDDFNLFKAQVEQVLKAEKIKLSAAE
KNAIVNAVSWYDETAARVINKTVKLNGDKLQDLLARLECEAEDLPDFGFYPSGKKDEYIIYDSSADLRDTESVPLKQSIY
QYFLDEVKPHVAEAWINLDSVKIGYEISFNKYFYHPKPLRSLEEVAQDIIKLEQQSEGLIAQILGVSVDKIQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1769 NP_231404.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 76
VC0395_A1367 YP_001217310.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 76
VPI2_0017c ACA01834.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 76

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hsdM YP_005804550.1 type I restriction-modification system DNA methylase VFG1102 Protein 0.0 76