Gene Information

Name : aacA4 (ABTW07_3883)
Accession : YP_005797131.1
Strain : Acinetobacter baumannii TCDC-AB0715
Genome accession: NC_017387
Putative virulence/resistance : Resistance
Product : aminoglycoside 6'-N-acetyl transferase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 265409 - 266041 bp
Length : 633 bp
Strand : +
Note : -

DNA sequence : 
ATGTTACGCAGCAGCAACGATGTTACGCAGCAGGGCAGTCGCCCTAAAACAAAGTTAGGCATCACAAAGTACAGCATCGT
GACCAACAGCAACGATTCCGTCACACTGCGCCTCATGACTGAGCATGACCTTGCGATGCTCTATGAGTGGCTAAATCGAT
CTCATATCGTCGAGTGGTGGGGCGGAGAAGAAGCACGCCCGACACTTGCTGACGTACAGGAACAGTACTTGCCAAGCGTT
TTAGCGCAAGAGTCCGTCACTCCATACATTGCAATGCTGAATGGAGAGCCGATTGGGTATGCCCAGTCGTACGTTGCTCT
TGGAAGCGGGGACGGATGGTGGGAAGAAGAAACCGATCCAGGAGTACGCGGAATAGACCAGTTACTGGCGAATGCATCAC
AACTGGGCAAAGGCTTGGGAACCAAGCTGGTTCGAGCTCTGGTTGAGTTGCTGTTCAATGATCCCGAGGTCACCAAGATC
CAAACGGACCCGTCGCCGAGCAACTTGCGAGCGATCCGATGCTACGAGAAAGCGGGGTTTGAGAGGCAAGGTACCGTAAC
CACCCCAGATGGTCCAGCCGTGTACATGGTTCAAACACGCCAGGCATTCGAGCGAACACGCAGTGTTGCCTAA

Protein sequence : 
MLRSSNDVTQQGSRPKTKLGITKYSIVTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLADVQEQYLPSV
LAQESVTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQLLANASQLGKGLGTKLVRALVELLFNDPEVTKI
QTDPSPSNLRAIRCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aacA4 AFG30111.1 aminoglycoside 6'-N-acetyl transferase type Ib Not tested PAGI-2 Protein 8e-78 100
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase Not tested AbaR4e Protein 9e-95 100
aacA4 AET25388.1 aminoglycoside 6'-N-acetyl transferase type Ib Not tested PAGI-2(C) Protein 8e-78 100
ACICU_00223 YP_001844882.1 aminoglycoside 6'-N-acetyl transferase type Ib Not tested AbaR20 Protein 3e-94 100
aacA4 ADZ05804.1 aminoglycoside 6'-N-acetyltransferase Not tested AbaR3 Protein 3e-77 100
aacA4 CAB46687.2 aminoglucoside acetyl-transferase Not tested Not named Protein 4e-73 99
aacA4 ACY75533.1 aminoglycoside acetyl transferase Not tested Tn6060 Protein 2e-76 99

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase EF118171.1.gene3.p01 Protein 4e-78 100
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase GQ202693.1.gene3.p01 Protein 2e-77 100
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AY162283.2.gene2.p01 Protein 2e-77 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AJ584652.2.gene6.p01 Protein 5e-82 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AY123251.gene1.p01 Protein 2e-77 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AF231133.1.gene2.p01 Protein 2e-81 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AM412777.1.gene2.p01 Protein 2e-81 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AY007784.1.gene2.p01 Protein 4e-82 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase FJ790516.1.gene2.p01 Protein 4e-82 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase HQ111474.1.gene2.p01 Protein 4e-82 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase FJ848783.1.gene2.p01 Protein 2e-81 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AF318077.1.gene1.p01 Protein 4e-82 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase FJ854362.1.gene3.p01 Protein 4e-82 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AF317511.1.gene4.p01 Protein 8e-77 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase Y18050.2.gene4.p01 Protein 2e-73 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AY033653.3.gene4.p01 Protein 8e-77 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase EF636461.1.orf1.gene Protein 2e-75 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AF371964.1.gene2.p1 Protein 8e-77 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AF317511.1.gene3.p01 Protein 8e-77 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AF024602.1.gene2.p01 Protein 2e-73 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AY033653.3.gene5.p01 Protein 8e-77 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase EF375620.1.orf0.gene Protein 2e-75 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AF322577.2.gene3.p01 Protein 8e-77 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AF315351.1.gene3.p01 Protein 8e-77 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase U59183.1.gene2.p01 Protein 1e-89 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AY103455.gene.p01 Protein 1e-82 99
aacA4 YP_005797131.1 aminoglycoside 6'-N-acetyl transferase AY123251.gene5.p01 Protein 8e-71 77