Gene Information

Name : ABTW07_2427 (ABTW07_2427)
Accession : YP_005799309.1
Strain : Acinetobacter baumannii TCDC-AB0715
Genome accession: NC_017387
Putative virulence/resistance : Resistance
Product : dihydropteroate synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2570608 - 2571537 bp
Length : 930 bp
Strand : +
Note : -

DNA sequence :
ATGGTGAAGTCTTCTTTATGCGTGAACAGGCTCGACAATTATGGAGCTTTTGGAATAAAGCCAAAGCTCAGGCGGTGCTT
ATCGTGTACAGAGATTATTATTATAGAAGCCCCCATGAATAAATCGCTCATCATTTTCGGCATCGTCAACATAACCTCGG
ACAGTTTCTCCGATGGAGGCCGGTATCTGGCGCCAGACGCAGCCATTGCGCAGGCGCGTAAGCTGATGGCCGAGGGGGCA
GATGTGATCGACCTCGGTCCGGCATCCAGCAATCCCGACGCCGCGCCTGTTTCGTCCGACACAGAAATCGCGCGTATCGC
GCCGGTGCTGGACGCGCTCAAGGCAGATGGCATTCCCGTCTCGCTCGACAGTTATCAACCCGCGACGCAAGCCTATGCCT
TGTCGCGTGGTGTGGCCTATCTCAATGATATTCGCGGTTTTCCAGACGCTGCGTTCTATCCGCAATTGGCGAAATCATCT
GCCAAACTCGTCGTTATGCATTCGGTGCAAGACGGGCAGGCAGATCGGCGCGAGGCACCCGCTGGCGACATCATGGATCA
CATTGCGGCGTTCTTTGACGCGCGCATCGCGGCGCTGACGGGTGCCGGTATCAAACGCAACCGCCTTGTCCTTGATCCCG
GCATGGGGTTTTTTCTGGGGGCTGCTCCCGAAACCTCGCTCTCGGTGCTGGCGCGGTTCGATGAATTGCGGCTGCGCTTC
GATTTGCCGGTGCTTCTGTCTGTTTCGCGCAAATCCTTTCTGCGCGCGCTCACAGGCCGTGGTCCGGGGGATGTCGGGGC
CGCGACACTCGCTGCAGAGCTTGCCGCCGCCGCAGGTGGAGCTGACTTCATCCGCACACACGAGCCGCGCCCCTTGCGCG
ACGGGCTGGCGGTATTGGCGGCGCTGAAAGAAACCGCAAGAATTCGTTAA

Protein sequence :
MVKSSLCVNRLDNYGAFGIKPKLRRCLSCTEIIIIEAPMNKSLIIFGIVNITSDSFSDGGRYLAPDAAIAQARKLMAEGA
DVIDLGPASSNPDAAPVSSDTEIARIAPVLDALKADGIPVSLDSYQPATQAYALSRGVAYLNDIRGFPDAAFYPQLAKSS
AKLVVMHSVQDGQADRREAPAGDIMDHIAAFFDARIAALTGAGIKRNRLVLDPGMGFFLGAAPETSLSVLARFDELRLRF
DLPVLLSVSRKSFLRALTGRGPGDVGAATLAAELAAAAGGADFIRTHEPRPLRDGLAVLAALKETARIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sul2 AEA34678.1 dihydropteroate synthase Not tested Not named Protein 2e-112 100
sulI2 AFV47959.1 sulphonamide-insensitive dihydropteroate synthase SulI2 Not tested AbaR25 Protein 2e-112 100
sul2 YP_005176181.1 dihydropteroate synthase Not tested ICEPmu1 Protein 8e-95 100
sul2 AEZ06044.1 Sul2, sulphonamide-insensitive dihydropteroate synthase Not tested Tn6167 Protein 3e-112 100
ABK1_0255 YP_005512827.1 Dihydropteroate synthase type-2 Not tested AbaR4d Protein 2e-117 100
BJAB07104_00246 YP_008207711.1 Dihydropteroate synthase-related enzyme Not tested AbaR25 Protein 2e-117 100
BJAB0868_00253 YP_008211579.1 Dihydropteroate synthase-related enzyme Not tested AbaR26 Protein 6e-117 99
sul1 AFV53112.1 dihydropteroate synthase Not tested AbGRI2-1 Protein 1e-53 53
sul1 AGF34990.1 Sul1 dihydropteroate synthase Not tested SGI1 Protein 1e-53 53
sul1 AAG03004.2 sulfonamide resistance protein Not tested SGI1 Protein 1e-53 53
sul1 AGK36648.1 Sul1 Not tested AbaR26 Protein 1e-53 53
sul1 AGF35029.1 Sul1 dihydropteroate synthase Not tested SGI1 Protein 1e-53 53
sul1 ABB48429.1 sulfonamide insensitive dihydropteroate synthase Not tested SGI1 Protein 1e-53 53
sul1 ADZ05750.1 dihydropteroate synthase Not tested AbaR10 Protein 9e-54 53
sul1 AGF35064.1 Sul1 dihydropteroate synthase Not tested SGI1 Protein 1e-53 53
sul1 ACY75524.1 Sul1 Not tested Tn6060 Protein 1e-53 53
ACICU_00228 YP_001844887.1 dihydropteroate synthase Not tested AbaR20 Protein 1e-53 53
sul1 AGK06934.1 Sul1 dihydropteroate synthase Not tested SGI1 Protein 1e-53 53
sul1 ACY75531.1 Sul1 Not tested Tn6060 Protein 1e-53 53
sul1 YP_005797135.1 sulfonamide-resistant dihydropteroate synthase Not tested AbaR4e Protein 1e-53 53
sul1 AGK06980.1 Sul1 dihydropteroate synthase Not tested SGI1 Protein 1e-53 53
sul1 ADI24148.1 dihydropteroate synthase Not tested AbaR1 Protein 1e-53 53
sul1 YP_005797151.1 sulfonamide-resistant dihydropteroate synthase Not tested AbaR4e Protein 1e-53 53
sul1 AGK07017.1 Sul1 dihydropteroate synthase Not tested SGI1 Protein 1e-53 53
sul1 ADZ05756.1 dihydropteroate synthase Not tested AbaR10 Protein 1e-53 53
sulI YP_006098378.1 dihydropteroate synthase type-1 Not tested Tn2411 Protein 1e-53 53
sul1 AGK07075.1 Sul1 dihydropteroate synthase Not tested SGI1 Protein 1e-53 53
sul1 AET25390.1 Sul1 Not tested PAGI-2(C) Protein 1e-53 53
sul1 ADZ05806.1 dihydropteroate synthase Not tested AbaR20 Protein 2e-53 53
sul1 ACN81027.1 Sul1, sulfonamide-resistant dihydropteroate synthase Not tested AbaR5 Protein 1e-53 53
sul1 AGK07110.1 Sul1 dihydropteroate synthase Not tested SGI1 Protein 1e-53 53
sul1 AFG30113.1 Sul1 Not tested PAGI-2 Protein 1e-53 53
sul1 ACN81038.2 Sul1, sulfonamide-resistant dihydropteroate synthase Not tested AbaR5 Protein 1e-53 53
sul1 YP_005160002.1 dihydropteroate synthase Not tested Not named Protein 8e-54 52
sul1 ACS32048.1 Sul1; sulfonamide-insensitive dihydropteroate synthase Not tested SGI2 Protein 6e-54 52
sul1 ACF06160.1 dihydropteroate synthase Not tested Tn5036-like Protein 5e-54 51
sul1 ACF06164.1 dihydropteroate synthase Not tested Tn5036-like Protein 1e-53 51
sulI CAJ77050.1 sul1delta fusion protein Not tested AbaR1 Protein 2e-54 51
sulI CAJ77089.1 sul1delta fusion protein Not tested AbaR1 Protein 2e-54 51
sulI CAJ77053.1 sul1delta fusion protein Not tested AbaR1 Protein 1e-54 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ABTW07_2427 YP_005799309.1 dihydropteroate synthase DQ464881.1.gene2.p01 Protein 7e-111 99
ABTW07_2427 YP_005799309.1 dihydropteroate synthase AJ459418.gene.p01 Protein 9e-57 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase DQ143913.1.gene6.p01 Protein 1e-53 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase AF174129.3.gene6.p01 Protein 6e-54 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase U37105.2.gene6.p01 Protein 6e-54 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase AY162283.2.gene6.p01 Protein 6e-54 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase EF118171.1.gene7.p01 Protein 6e-54 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase AB061794.1.gene5.p01 Protein 6e-54 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase AF313471.1.gene7.p01 Protein 6e-54 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase AY339625.2.gene19.p0 Protein 6e-54 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase AY740681.1.gene7.p01 Protein 6e-54 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase HQ451074.1.gene20.p0 Protein 6e-54 53
ABTW07_2427 YP_005799309.1 dihydropteroate synthase NC_011586.7045208.p0 Protein 5e-53 52
ABTW07_2427 YP_005799309.1 dihydropteroate synthase AF191564.1.gene5.p01 Protein 3e-54 51
ABTW07_2427 YP_005799309.1 dihydropteroate synthase NC_011586.7045179.p0 Protein 5e-55 50