Gene Information

Name : cag26 (KHP_0771)
Accession : YP_005793164.1
Strain : Helicobacter pylori 51
Genome accession: NC_017382
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein A
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 821160 - 824693 bp
Length : 3534 bp
Strand : -
Note : similar to HP0547

DNA sequence :
ATGACTAATGAAACCATTGATCAAACAACAACACCAGATCAAACACTAAACCAAACGGATTTTGTTCCGCAACGATTTAT
CCATAATCTTCAAGTAGCTTTTATCAAAGTTGATAACGCTGTCGCTTCATTTGATCCTGATCAAAAACCAATCGTTGATA
AGAATGATAGGGATAACAGGCAAGCTTTTGAGAAAATCTCGCAGCTAAGGGAAGAATACGCCAATAAAGCGATCAAAAAT
CCTGCCAAAAAGAATCAGTATTTTTCAGACTTTATCAATAAGAGCAATGATTTGATCAACAAAGACAATCTCATTGCTGT
AGATTCTTCCGTAGATAGCTTTCGGAAATTTGGGGATCAGCGTTACCAAATTTTTACGAGTTGGGTGTCTCTTCAAAAAG
ATCCGTCTAAAATCAACACCCAACAAATCCGAAATTTTATGGAAAATATCATACAACCCCCTATCTCTGATGATAAGGAA
AAAGCGGAGTTTTTGAGGTCTGCCAAACAATCTTTTGCAGGAATTATCATAGGGAACCAAATCCGATCGGATGAAAAATT
CATGGGCGTGTTTGATGAATCTTTGAAAGCAAGGCAAGAAGCAGAAAAAAATGCAGAGCCTGCTGGTGGGGATTGGCTTG
ATATTTTTTTATCATTTGTATTCAACAAAAAACAATCTTCCGATCTCAAAGAAACGCTCAATCAAGAGCCAAGGCCTGAT
TTTGAACAAAATTTAGCCACTACCACAACCGACATACAAGGCTTACCGCCTGAAGCTAGAGATTTGCTTGATGAAAGGGG
TAATTTTTCTAAATTCACTCTTGGTGATATGGAAATGTTGGATGTTGAGGGAGTCGCTGACAAGGATCCCAATTACAAGT
TTAATCAATTATTGATCCACAATAACGCTTTATCTTCTGTGCTAATGGGGGGTCATAGTAACATAGAACCTGAAAAGGTT
TCATTATTGTATGGGGATAATGGTGGTCCTGAAGCTAGGCATGATTGGAACGCCACCGTTGGTTATAAAAATCAACAAGG
CAACAATGTGGCCACACTCATTAATGCGCATCTTAATAACGGCAGCGGGTTAATCATAGCGGGTAATGAGGATGGGATTA
AAAATCCTAGCTTCTATCTCTACAAAGAAGACCAACTCACAGGCTTGAAACAAGCAATGAGTCAAGAAGAGATCCAAAAC
AAAGTAGATTTCATGGAATTTCTTGCGCAAAACAACGCTAAATTAGATAACTTGAGCGAGAAAGAGAAAGAAAAATTCCA
AACTGAGATTGAAAATTTCCAAAAAGACCGTAAGGCTTATTTGGACGCTCTAGGGAATGATCGCATTGCTTTTGTTTCTA
AAAAAGACCCAAAACATTTAGCTTTGGTTACTGAGTTTGGTAATGGGGAAGTGAGCTATACCCTCAAGGATTATGGGAAA
AAACAAGATAAAGCTTTAGATGGGGAGACAAAAACCACTCTTCAAGGTAACCTAAAATATGATGGCGTGATGTTTGTCAA
TTATTCCAATTTCAAATACACCAACGCCTCCAAGAGTCCTGATAAGGGTATAGGCACTACGAATGGCGTTTCCCATTTGG
AAGCAAATTTTAGCAAAGTAGCTGTCTTTAATTTGCCTAATTTAAATAATCTCGCTATCACTAATTATATAAGGCGAGAT
TTAGAAGAGAAATTGTGGGCTAAAGGATTGTCCCTACAAGAAGCTAATAAGCTCATCAAAGACTTTTTGAACAGCAACAA
AGAAATGGTTAGAAAAGTTTCAAACTTCAATAAAGCTGTAGCTGAAGCTAAAAACACAGGCAATTATGATGGAGTGAAAA
AAGCTCAGAAAGATCTTGAAAAATCTCTAAGGAAACGAGAGCATTTAGAGAAAGAAGTAGCGAAAAAATTGGAGAGCAGA
AACGACAACAAAAATAAAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGATAAGATTTTTGCACTTATCAATAAAGA
GGCTAGTAAGGAAGCAAGAGCGGCCGCTTTCGATCCGAATCTTAAAGGCATCAGGAGCGAATTGTCTGATAAACTTGAAA
ATATCAACAAGAATTTGAAAGACTTTGGCAAATCTTTTGATGAACTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGCA
GAAGAAACGCTAAAAGCCCTTAAAGACTCGGTGAAAGATTTAGGCATCAATCCAGAATGGATTTCAAAAATTGAAAACCT
TAATGCAGCTTTGAATGATTTCAAAAATGGCAAAAATAAGGATTTCAGTAAGGTAACACAAGCAAAAAGCGACCTTGAAA
ATTCCATTAAGGATGTGATCATTAATCAAAAGATAACGGATAAAGTTGACAATCTCAATCAGGCTGTATCAGAGACTAAA
TTAACAGGCGATTTCAGTAAGGTAGAGCAAGCCCTAGCCGAACTCAAAAGCTTGTCATTGGATCTTGGAAAAAATTCTGA
TCTACAAAAATCCGTTAAAAATGGTGTAAATGGAACCCTAGTCGGTAATGGGTTATCTAAAACAGAAGCCACAACGCTCA
CCAAAAATTTTTCGGACATCAGGAAAGAATTGAACGAGAAGTTATTTGGAAATTCCAATAACAATAATAATGGACTCAAA
AACAACACAGAGCCTATTTACGCTCAAGTTAATAAAAAGAAAACAGGACAAGCAGCTAGCCCTGAAGAGTCCATTTACGC
TCAAGTTGCTAAAAAGGTGAGTGCAAAAATTGACCAACTCAACGAATCTGCATCAGCAATAAATAGAAAAATTGACCGGA
TTAACAAAATTGCATCAGCAGGTAAAGGAGTGGGCGGTTTCAGTGGAGCAGGGCGATCAGCTAGCCCTGAACCCATTTAC
GCTACAATTGATTTTGATGAGGCAAATCAAGCAGGCTTCCCTTTGAGGAGATACGCTCCAGTTGATGATCTCAGTAAAGT
AGGGCTTTCAAGGGAACAAGAATTGACTCGTAGAATTGGCGATCTCAATCAGGCGGTATCAGAAGCTAAAATAGGTCATT
TTGATAACCTAGAACAAAAGATAGATGAACTCAAAGATTCTACGAAAAAGAATGCTTTGAAGCTATGGGTTGAAAGCGCG
AAACAAGTGCCTACTGGTTTGCAAGCGAAATTGGACAATTACGCTACTAACAGCCACACACGCATTAATAGCAATGTCCA
AACTGGAGCGATCAATGAAAAAGCGACCGGCATGCTAACGCAAAAAAACCCTGAGTGGCTCAAGCTCGTGAATGATAAGA
TAGTTGCACATAATGTGGGAAGTGCTCATTTGTCAGAGTATGATAAAATTGGATTCAACCAAAAGAATATGAAAGATTAT
TCTGATTCGTTCAAGTTTTCCACCAAGTTGAACAACGCCGTAAAAGACATTAAGTCTAGCTTTGTGCAATTTTTAACCAA
TACATTTTCTACAGGATCTTACAGCTTGATGAAAGCAAATGCGGAACATGGAGTCAAAAATACTAATACAAAAGGTGGTT
TCCAAAAATCTTAA

Protein sequence :
MTNETIDQTTTPDQTLNQTDFVPQRFIHNLQVAFIKVDNAVASFDPDQKPIVDKNDRDNRQAFEKISQLREEYANKAIKN
PAKKNQYFSDFINKSNDLINKDNLIAVDSSVDSFRKFGDQRYQIFTSWVSLQKDPSKINTQQIRNFMENIIQPPISDDKE
KAEFLRSAKQSFAGIIIGNQIRSDEKFMGVFDESLKARQEAEKNAEPAGGDWLDIFLSFVFNKKQSSDLKETLNQEPRPD
FEQNLATTTTDIQGLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADKDPNYKFNQLLIHNNALSSVLMGGHSNIEPEKV
SLLYGDNGGPEARHDWNATVGYKNQQGNNVATLINAHLNNGSGLIIAGNEDGIKNPSFYLYKEDQLTGLKQAMSQEEIQN
KVDFMEFLAQNNAKLDNLSEKEKEKFQTEIENFQKDRKAYLDALGNDRIAFVSKKDPKHLALVTEFGNGEVSYTLKDYGK
KQDKALDGETKTTLQGNLKYDGVMFVNYSNFKYTNASKSPDKGIGTTNGVSHLEANFSKVAVFNLPNLNNLAITNYIRRD
LEEKLWAKGLSLQEANKLIKDFLNSNKEMVRKVSNFNKAVAEAKNTGNYDGVKKAQKDLEKSLRKREHLEKEVAKKLESR
NDNKNKMEAKAQANSQKDKIFALINKEASKEARAAAFDPNLKGIRSELSDKLENINKNLKDFGKSFDELKNGKNKDFSKA
EETLKALKDSVKDLGINPEWISKIENLNAALNDFKNGKNKDFSKVTQAKSDLENSIKDVIINQKITDKVDNLNQAVSETK
LTGDFSKVEQALAELKSLSLDLGKNSDLQKSVKNGVNGTLVGNGLSKTEATTLTKNFSDIRKELNEKLFGNSNNNNNGLK
NNTEPIYAQVNKKKTGQAASPEESIYAQVAKKVSAKIDQLNESASAINRKIDRINKIASAGKGVGGFSGAGRSASPEPIY
ATIDFDEANQAGFPLRRYAPVDDLSKVGLSREQELTRRIGDLNQAVSEAKIGHFDNLEQKIDELKDSTKKNALKLWVESA
KQVPTGLQAKLDNYATNSHTRINSNVQTGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSAHLSEYDKIGFNQKNMKDY
SDSFKFSTKLNNAVKDIKSSFVQFLTNTFSTGSYSLMKANAEHGVKNTNTKGGFQKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cagA BAC10421.1 CagA Virulence cag PAI Protein 0.0 97
HP0547 BAD13799.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 97
cagA YP_005779046.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 97
cagA BAC10430.1 CagA Virulence cag PAI Protein 0.0 97
cagA BAC10426.1 CagA Virulence cag PAI Protein 0.0 96
cagA YP_005777288.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 96
cagA BAC10420.1 CagA Virulence cag PAI Protein 0.0 96
cagA BAC10435.1 CagA Virulence cag PAI Protein 0.0 96
HP0547 BAD14072.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 96
cagA BAD51755.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 96
cagA BAD51744.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 96
cagA BAC10431.1 CagA Virulence cag PAI Protein 0.0 96
HP0547 BAD13963.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 96
cagA YP_005775747.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 96
cagA YP_005774524.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 96
cagA BAD51754.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 96
HP0547 BAD13880.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 96
cagA AAF17597.1 CagA Virulence cag PAI Protein 0.0 96
cagA BAD51749.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 96
cagA BAD51762.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 96
cagA BAC10433.1 CagA Virulence cag PAI Protein 0.0 96
HP0547 BAD14018.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 96
cagA BAC10424.1 CagA Virulence cag PAI Protein 0.0 96
cagA BAC10419.1 CagA Virulence cag PAI Protein 0.0 95
cagA BAC10422.1 CagA Virulence cag PAI Protein 0.0 93
HP0547 BAD13826.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 93
HP0547 BAD13853.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 90
cagA BAC10427.1 CagA Virulence cag PAI Protein 0.0 88
cagA BAD51764.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA BAC10423.1 CagA Virulence cag PAI Protein 0.0 83
cagA BAD51752.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 82
cagA BAD51756.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 82
cagA AGC69806.1 cag pathogenicity island protein A Virulence cag PAI Protein 0.0 82
cagA BAD51759.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA BAC10429.1 CagA Virulence cag PAI Protein 0.0 81
HP0547 BAD13935.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 81
cagA BAD51758.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA BAD51760.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA BAD51753.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA YP_003728762.1 cytotoxin-associated protein A Virulence cag PAI Protein 0.0 81
cagA BAD51766.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 81
cagA BAD51751.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 80
cagA BAD51761.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 80
cagA BAD51750.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 80
HP0547 NP_207343.1 cag pathogenicity island protein (cag26) Virulence cag PAI Protein 0.0 79
cagA AAR03970.1 CagA Virulence cag PAI Protein 0.0 79
cagA AAR03939.1 CagA Virulence cag PAI Protein 0.0 79
cagA NP_223213.1 cag island protein, cytotoxicity associated immunodominant antigen Virulence cag PAI Protein 0.0 78
cagA AAR03909.1 CagA Virulence cag PAI Protein 0.0 78
HP0547 BAD13908.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA BAC10428.1 CagA Virulence cag PAI Protein 0.0 78
cagA AAR03881.1 CagA Virulence cag PAI Protein 0.0 78
cagA AAC44706.1 CagA Virulence cag PAI Protein 0.0 77
HP0547 BAD14045.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 77
cagA BAD51747.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 77
HP0547 BAD13990.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 75
cagA BAC10432.1 CagA Virulence cag PAI Protein 0.0 75
cagA AAF17598.1 CagA Virulence cag PAI Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cag26 YP_005793164.1 cag pathogenicity island protein A VFG0306 Protein 0.0 79