Gene Information

Name : ureA (hp2018_0078)
Accession : YP_005790889.1
Strain : Helicobacter pylori 2018
Genome accession: NC_017381
Putative virulence/resistance : Virulence
Product : Urease alpha subunit
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 72634 - 74343 bp
Length : 1710 bp
Strand : -
Note : -

DNA sequence :
ATGAAAAAGATTAGCAGAAAAGAATATGTTTCTATGTATGGCCCTACCACAGGCGATAAAGTGAGATTGGGCGATACAGA
TTTGATTGCTGAAGTAGAACATGACTACACCATTTACGGCGAAGAGCTTAAATTCGGTGGCGGTAAAACCCTAAGAGAAG
GCATGAGCCAATCCAACAACCCTAGCAAAGAAGAACTGGATTTGATCATCACTAACGCTTTAATCGTGGATTACACCGGT
ATTTATAAAGCGGATATTGGTATTAAAGACGGCAAAATCGCTGGCATTGGTAAAGGCGGTAACAAAGACATGCAAGATGG
CGTTAAAAACAATCTTAGCGTGGGTCCTGCTACTGAAGCGCTAGCCGGTGAAGGCTTGATCGTAACGGCTGGTGGTATTG
ACACACACATCCACTTCATTTCACCCCAACAAATCCCCACAGCTTTTGCAAGCGGTGTAACAACCATGATTGGTGGCGGA
ACCGGTCCTGCTGATGGCACTAATGCGACTACTATCACTCCAGGTAGAAGAAACTTAAAATGGATGCTCAGAGCGGCTGA
AGAATATTCTATGAACTTAGGTTTCTTAGCTAAAGGCAACACTTCTAACGATGCGAGCTTAGCCGATCAAATTGAAGCCG
GTGCGATTGGCTTTAAAATCCACGAAGACTGGGGCACCACTCCTTCTGCAATCAATCATGCGTTAGACGTTGCGGACAAA
TACGATGTGCAGGTCGCTATCCACACAGACACTTTGAATGAAGCCGGTTGTGTAGAAGACACTATGGCTGCTATTGCCGG
ACGCACTATGCACACTTTCCACACTGAAGGCGCTGGTGGCGGACACGCTCCTGATATTATTAAAGTGGCCGGTGAACACA
ACATCCTACCCGCTTCCACTAACCCCACTATCCCTTTCACCGTGAATACAGAAGCCGAACACATGGACATGCTTATGGTG
TGCCACCACTTGGATAAAAGCATTAAAGAAGATGTCCAGTTCGCTGATTCAAGAATCCGCCCTCAAACCATTGCGGCTGA
AGACACTTTGCATGACATGGGGATTTTCTCCATCACCAGTTCTGACTCTCAAGCGATGGGCCGTGTGGGTGAAGTTATCA
CTAGAACTTGGCAAACAGCTGACAAAAACAAAAAAGAATTTGGCCGCTTGAAAGAAGAAAAAGGCGATAACGACAACTTC
AGGATCAAACGCTACTTGTCTAAATACACCATTAACCCAGCGATCGCTCATGGGATTAGCGAGTATGTAGGTTCAGTAGA
AGTGGGCAAAGTGGCTGACTTGGTATTGTGGAGTCCAGCATTCTTTGGCGTGAAACCCAACATGATCATCAAAGGCGGAT
TCATTGCGTTAAGCCAAATGGGCGATGCGAACGCTTCTATCCCTACCCCACAACCGGTTTATTACAGAGAAATGTTCGCT
CACCATGGTAAAGCTAAATACGATGCAAACATCACTTTTGTGTCCCAAGCGGCTTATGACAAAGGCATTAAAGAAGAATT
AGGGCTTGAAAGACAAGTGTTACCGGTAAAAAATTGCAGAAACATCACTAAAAAAGACATGCAATTCAACGACACTACCG
CTCACATTGAAGTCAATCCTGAAACTTACCATGTGTTCGTGGATGGCAAAGAAGTCACTTCTAAACCAGCCAATAAAGTG
AGCTTGGCTCAACTCTTTAGCATTTTCTAG

Protein sequence :
MKKISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTG
IYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLAKGNTSNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKV
SLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 4e-157 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 4e-157 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-146 59
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-146 59
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-146 59
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-146 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureA YP_005790889.1 Urease alpha subunit VFG0270 Protein 0.0 99