Gene Information

Name : cag3 (hp2018_0505)
Accession : YP_005791333.1
Strain : Helicobacter pylori 2018
Genome accession: NC_017381
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 500699 - 502144 bp
Length : 1446 bp
Strand : +
Note : -

DNA sequence :
ATGTTTAGAAAACTAGCAACCTCTGTATCGCTCATGGGCTTACTAATCTCCAACGCTCTTTATACTAAAGAAATAAGTGA
AGCCGATAAGGTCATTAAGGCCACTAAAGAAACTAAAGAGACCAAGCAAGAGGCTAAACGCCTCAAAAAAGAAGCTAAAC
AGCGCCAACAGATCCCTGATAATAAGAAACCTCAATATGTCTCTGTTGATGACACAAAAACTCAAGCGCTTTTTGATATA
TACGACACCTTGAACGTGAATGACAAAAGCTTTGGGGATTGGTTTGGTAATAGCGCTTTGAAAGACAAAACTTATCTCTA
CGCTATGGATCTGTTGGATTATAACAACTACTTATCCATAGAAAACCCTATTATCAAAACAAGAGCGATGGGAACTTATG
CGGATCTCATTATCATCACAGGTTCGTTAGAACAAGTCAATGGGTATTACAACATTCTAAAAGCGCTCAACAAACGCAAC
GCTAAGTTTGTGTTAAAAATCAATGACAAAATACCTTACGCTCAAGCGACTTTTTTGAGAGTGCCAAAAAGAAGCGATCC
CAATTCTCACACGCTTGATAAGGGAGCGTCAATTGATGAAAGCAAGCTTTTTGAACAACAAAAGAAAATGTATTTCAACT
ACGCTAACGATGTGATCTGCAGACCCAACGATGAAGTGTGTTCGCCCCTAAGAGATGAAATGGTAGCTATGCCCACTAAC
GATAGCGTTACTCAAAAACCCAATATCATTGCTCCTTATAGCTTGTATAGGCTAAAAGAGACAAATAACGCCAATGAAGC
CCAACCATCACCTTATGCCACTCAAACCGCTCCTGAAAACAGCAAAGAGAAGCTCATAGAGGAGCTAATCGCCAACTCCC
AACTCATAGCCAATGAAGAAGAGAGGGAAAAGAAACTCTTAGCAGAAAAAGAAAAACAAGAGACTGAATTGGCTAAATAC
AAGCTCAAAGATTTAGAAAATCAAAAGAAACTAAAAGCTTTAGAAGCAGAGTTGAAAAAGAAAAACGCTAAGAAACCTAG
AGTAGTGGAAGTGCCTATTTCTCCTAAAACAAGTGATTCTGATGAAACAATGAGAGTTATCAAAGAAAAAGAAAACTATA
ATGGGTTATTAGTGGATAAAGAAACCACGATCAAAAGAAGCTATGAGGGGACTTTGATCAGTGAAAATTCTTACAGCAAA
AAAACACCCATCAACCTTGAGGACTTGAGAAACTTAGAAGAAGAAATTAAGAGCTACTATATCAAGTCTAATGGCTTGTG
TTACGCTAATGGCATTAGTCTCTATGTAAAAATCAAAAATGATCCCTACAAAGAGGGAATGCTGTGTGGTTATGAGAGCG
TTCAAAATCTGCTCTCACCACTAAGGGACAAGCTCAAATACGACAAGCAGAAGTTACAAAAAGCGTTACTGAAAGATTCA
AAGTAA

Protein sequence :
MFRKLATSVSLMGLLISNALYTKEISEADKVIKATKETKETKQEAKRLKKEAKQRQQIPDNKKPQYVSVDDTKTQALFDI
YDTLNVNDKSFGDWFGNSALKDKTYLYAMDLLDYNNYLSIENPIIKTRAMGTYADLIIITGSLEQVNGYYNILKALNKRN
AKFVLKINDKIPYAQATFLRVPKRSDPNSHTLDKGASIDESKLFEQQKKMYFNYANDVICRPNDEVCSPLRDEMVAMPTN
DSVTQKPNIIAPYSLYRLKETNNANEAQPSPYATQTAPENSKEKLIEELIANSQLIANEEEREKKLLAEKEKQETELAKY
KLKDLENQKKLKALEAELKKKNAKKPRVVEVPISPKTSDSDETMRVIKEKENYNGLLVDKETTIKRSYEGTLISENSYSK
KTPINLEDLRNLEEEIKSYYIKSNGLCYANGISLYVKIKNDPYKEGMLCGYESVQNLLSPLRDKLKYDKQKLQKALLKDS
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orf8 NP_223189.1 cag island protein Virulence cag PAI Protein 8e-175 98
HP0522 BAD13828.1 cag pathogenicity island protein Virulence cag PAI Protein 7e-172 95
HP0522 BAD13910.1 cag pathogenicity island protein Virulence cag PAI Protein 7e-172 95
HP0522 BAD13774.1 cag pathogenicity island protein Virulence cag PAI Protein 6e-172 95
cag3 YP_005779068.1 cag pathogenicity island protein Virulence cag PAI Protein 8e-172 95
cag3 AGC69793.1 cag pathogenicity island protein 3 Virulence cag PAI Protein 4e-172 95
cag3 YP_003728744.1 cag pathogenicity island protein delta Virulence cag PAI Protein 5e-172 95
HP0522 BAD14021.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-172 95
HP0522 NP_207318.1 cag pathogenicity island protein (cag3) Virulence cag PAI Protein 2e-172 95
cag3 AAR03914.1 Cag3 Virulence cag PAI Protein 2e-172 95
cag3 AAR03854.1 Cag3 Virulence cag PAI Protein 1e-172 95
HP0521 BAD13993.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-169 95
HP0521 BAD13965.1 cag pathogenicity island protein Virulence cag PAI Protein 6e-169 95
cag3 YP_005777266.1 cag pathogenicity island protein Virulence cag PAI Protein 8e-171 94
HP0522 BAD13855.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-170 94
cag3 YP_005774547.1 cag pathogenicity island protein Virulence cag PAI Protein 4e-171 94
cag-delta AAF80193.1 Cag-delta Virulence cag PAI Protein 7e-171 94
HP0522 BAD13938.1 cag pathogenicity island protein Virulence cag PAI Protein 5e-171 94
HP0522 BAD13801.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-171 94
HP0522 BAD14047.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-171 94
HP0522 BAD13883.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-171 94
cag3 YP_005775725.1 cag pathogenicity island protein Virulence cag PAI Protein 4e-170 94
cag3 AAR03885.1 Cag3 Virulence cag PAI Protein 8e-169 94
cag3 AAR03945.1 Cag3 Virulence cag PAI Protein 9e-171 94

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cag3 YP_005791333.1 cag pathogenicity island protein VFG0282 Protein 7e-173 95