Gene Information

Name : ureB (HPPN135_05410)
Accession : YP_005790265.1
Strain : Helicobacter pylori Puno135
Genome accession: NC_017379
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 1108810 - 1110513 bp
Length : 1704 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAACTTGATTATGTCAATACTTACGGGCCCACTAAAGGGGATAAAGTAAGATTAGGCGATACAGATCTTTGGGC
AGAAGTGGAGCATGATTACACTATCTATGGTGAAGAGTTAAAATTTGGTGCAGGCAAGACCATCAGAGAATGCATGGGGC
AAAGCAACAGCCATGACGAGAACACCTTAGATCTAGTGATCACCAACGCTCTCATTATTGATTACACCGGCATTTACAAA
GCTGATATTGGGATTAAAAACGGCAAGATTGCAGGCATTGGTAAAGCAGGCAATAAGGACATGCAAGATGGCGTCAGCCC
TAATTTAGTCGTAGGTGTAGGCACAGAAGCTTTAGCGGGTGAAGGCATGATTGTAACCGCTGGTGGGATTGATAGCCACA
CGCATTTTTTAAGTCCTCAACAATTCCCCACAGCTCTAGCTAATGGCGTGACCACGATGTTTGGCGGTGGTACTGGCCCG
GTAGATGGCACGAATGCGACCACTATCACTCCAGGAGAATGGAATATCCACAGAATGTTAAGAGCCGCTGAAGAATACGC
CATGAATGTGGGGTTTTTAGGGAAAGGGAATTCTTCTAGCAAAACCCAATTAGTGGAACAAATTGAAGCGGGTATTGTAG
GCTTTAAATTGCACGAAGATTGGGGTACCACTCCTAGCGCGATTGATACATGCTTAAGCGTCGCTGATGAATACGATGTG
CAAGTGTGCATCCATACAGACACCGTGAATGAAGCCGGGTATGTGGAAGACACGCTCAATGCAATGAACGGACGCGCTAT
CCATGCATACCACATTGAAGGGGCAGGTGGAGGACATAGCCCAGATGTTATCACTATGGCCGGTGAAGAAAACATCTTAC
CCAGTTCCACCACCCCAACCATTCCTTATACCATAAATACGGTTGCAGAACACTTAGACATGCTAATGACATGCCATCAT
TTGGATAAAAAAATCCGAGAAGATTTACAATTTTCCCAAAGCCGTATCCGCCCGGGTAGCATTGCAGCTGAAGATGTTTT
GCATGACAATGGCATGATCGCTATGACAAGTTCGGATTCTCAAGCGATAGGGAGAGCGGGTGAAGTCGTTCCCAGAACAT
GGCAAACCGCTGACAAAAACAAGAAAGAGTTTGGCCCTTTAAAAGAATACGATCAAAATGGGAATGATAATTTCCGCATC
AAACGCTACATTTCTAAATACACCATCAACCCGGCTATTACGCACGGCGTGAGCGAATACATCGGCTCTGTGGAAGCGGG
GAAAATCGCTGATTTAGTCGTGTGGAATCCGGCCTTTTTTGGGGTGAAACCTAAAATCATCATTAAAGGCGGTTTGGTCG
TGTTCTCTGAAATGGGCGATAGCAACGCTTCTGTGCCAACCCCACAACCTGTTTATTACAGAGAAATGTTTGGCCATCAT
GGGAAGGCTAAATTTGACACGAGCATCACTTTTGTCAATAAGCTCGCCTATGAAAAGGGCATTAAAGAAAAACTTGGCTT
AGAAAGACAAGTATTGCCCATCAAAAATGTGCGCAACATCACTAAAAAAGACTTTAAATTCAACAACACGATAGGAAAAC
TCACCGTCGATCCCAAAACCTTTGAAGTCTTTTTAGATGGCAAGCTTTGCACTTCCAAGCCAGCGAGCGAATTGCCTTTA
GCGCAACGCTACACTTTCTTTTAG

Protein sequence :
MKKLDYVNTYGPTKGDKVRLGDTDLWAEVEHDYTIYGEELKFGAGKTIRECMGQSNSHDENTLDLVITNALIIDYTGIYK
ADIGIKNGKIAGIGKAGNKDMQDGVSPNLVVGVGTEALAGEGMIVTAGGIDSHTHFLSPQQFPTALANGVTTMFGGGTGP
VDGTNATTITPGEWNIHRMLRAAEEYAMNVGFLGKGNSSSKTQLVEQIEAGIVGFKLHEDWGTTPSAIDTCLSVADEYDV
QVCIHTDTVNEAGYVEDTLNAMNGRAIHAYHIEGAGGGHSPDVITMAGEENILPSSTTPTIPYTINTVAEHLDMLMTCHH
LDKKIREDLQFSQSRIRPGSIAAEDVLHDNGMIAMTSSDSQAIGRAGEVVPRTWQTADKNKKEFGPLKEYDQNGNDNFRI
KRYISKYTINPAITHGVSEYIGSVEAGKIADLVVWNPAFFGVKPKIIIKGGLVVFSEMGDSNASVPTPQPVYYREMFGHH
GKAKFDTSITFVNKLAYEKGIKEKLGLERQVLPIKNVRNITKKDFKFNNTIGKLTVDPKTFEVFLDGKLCTSKPASELPL
AQRYTFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-137 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-137 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-137 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-137 58
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-141 57
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-141 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_005790265.1 urease subunit beta VFG0270 Protein 0.0 73