Gene Information

Name : guaA (HPPN135_05300)
Accession : YP_005790243.1
Strain : Helicobacter pylori Puno135
Genome accession: NC_017379
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1083054 - 1084580 bp
Length : 1527 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGTCAATACACACAGCTGATTGCTAGAAGATTGAGAGAGAGCGGGATTTATGCAGA
AATAGTCCCTTTTTTTGAAAGCATAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGTGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCCAGTGAAAAAATCTTTGATTTGGATTTGCCGATTTTAGGGATTTGCTACGGC
ATGCAGTATTTGGTGGATTTTTTTGGGGGGGTAGTGGCTTGCACGAATGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CATTCAAGATTCTGTGATTTTTGAAGGCGTGAAAATTAAAAGCCTTGTGTGGATGAGCCATATGGATAAAGTTATAGAAT
TGCCTAAAGGCTTCACTACCCTTGCAAAAAGCCCTAATTCCCCCCATTGCGCGATTGAAAGCGCTAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAAGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTGGTTTGTGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATGGCGCGCTTGAAAGAAAAAATTGCTAACGCTAAGGTTTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTATACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGTTTGTTGCGTAAAAATGAAAAAGAAAAAGTTCAAGCGATGTTTAAAGACTTGCAAATCCCTTTAAA
CACGATAGACGCTAAAGAAATCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAACGAAAAATCATCGGCG
AAACCTTTATTGAAGCGTTTGAAAAAGAAGCCAAGAAGCACCATTTAAAAGGCAAAATTGAGTTTTTAGCCCAAGGCACT
TTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACCCACCATAATGTGGGCGGACT
GCCTGAATGGATGGACTTTAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGTCCGTTTGTTGGGTAAGGAAT
TGGGCATTAGCCAGGATTTTTTGATGCGCCACCCCTTTCCAGGGCCTGGGCTTGCGATAAGGATTTTAGGCGAAGTCAGC
GAGAGTAAGATCAGATGCTTGCAAGAAGCGGATTTTATTTTTATAGAAGAGCTTAAAAAAGCCAATTTGTATGACAAGGT
TTGGCAAGCTTTTTGCGTGCTGTTGGATGTCAATTCTGTGGGGGTTATGGGAGATAATCGCACTTATGAAAACGCTATTT
GTTTAAGGGCGGTGAATGCGAGCGATGGCATGACAGCGAGCTTTTCATTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGTATCACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGATATTACCTCTAAACCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYAEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPSEKIFDLDLPILGICYG
MQYLVDFFGGVVACTNEQEFGKAVLEIIQDSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIESAKIFGL
QFHPEVIQSEEGGKILENFALLVCGCEKTWGMQHFAQREMARLKEKIANAKVLCAVSGGVDSTVVATLLYRAIKDNLIAV
FVDHGLLRKNEKEKVQAMFKDLQIPLNTIDAKEIFLSKLKGVSEPELKRKIIGETFIEAFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGISQDFLMRHPFPGPGLAIRILGEVS
ESKIRCLQEADFIFIEELKKANLYDKVWQAFCVLLDVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-132 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-132 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-132 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-115 48