Gene Information

Name : HPPN120_00550 (HPPN120_00550)
Accession : YP_005787808.1
Strain : Helicobacter pylori Puno120
Genome accession: NC_017378
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 108814 - 109956 bp
Length : 1143 bp
Strand : -
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGCGCATGCAAACAAAATTAATCCATGGGGGCATTAGTGAGGATGCGACAACGGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAGGACGCCATAGGCCGCCACAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAACTCATCGCTGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCCTCTGGATTAGCTGGAATCCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGCTATTGGGCGATGATGTCTATGGGGGGACTTTTCGCTTGTTCAATAA
AGTGCTTGTCAAAAACGGGCTTTCTTGCACCATTATAGACACTAGCGATCTATCCCAAATCAAAAAGGCTATCAAGCCCA
ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGTGCAATGCGCTAGTGTTGCT
AAAGATCATGGTTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGAGCGGA
CATTGTGGTGCATAGCGGCACCAAATACTTAGGCGGGCATAGCGATGTGGTCGCTGGGCTTGTAACCACTAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGCTGCAAAGA
GGGATTAAAACGCTAGGATTGCGCATGGAAGCCCATCAAAAAAACGCTCTTTGCGTGGCTGAGTTTTTAGAAAAACACCC
TAAAGTGGAGAGGGTTTATTACCCGGGCTTGAGCGCTCACCCTAACCACGAGCTGGCCAAAAAACAGATGCATGGCTTTA
GCGGGATGCTCTCTTTCACTCTCAAAAATGACAGCGAAGCGGTTGCTTTTGTAGAAAGCCTTAAATTATTCATTTTAGGC
GAGAGTTTGGGCGGGGTGGAAAGTTTGGTGGGGATTCCAGCATTCATGACCCATGCGTGTATCCCCAAAGCGCAACGAGA
AGCTGCCGGGATTAAAGATGGTCTGGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC
AAGCGTTCGCTAAAATAGGCTAA

Protein sequence :
MRMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLVQCASVA
KDHGLLTIVDNTFATPYCQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLSAHPNHELAKKQMHGFSGMLSFTLKNDSEAVAFVESLKLFILG
ESLGGVESLVGIPAFMTHACIPKAQREAAGIKDGLVRLSVGIEHEQDLLEDLEQAFAKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-97 55
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-99 55
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-73 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPPN120_00550 YP_005787808.1 cystathionine gamma-synthase BAC0207 Protein 3e-62 43