Gene Information

Name : ureB (HPSNT_00535)
Accession : YP_005786268.1
Strain : Helicobacter pylori Santal49
Genome accession: NC_017376
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 106908 - 108617 bp
Length : 1710 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAGATTAGCAGAAAAGAATATGTTTCTATGTATGGTCCTACCACAGGCGATAAAGTGAGATTGGGCGATACAGA
CTTGATCGCTGAAGTAGAACATGACTACACCATTTATGGCGAAGAGCTTAAATTCGGTGGCGGTAAAACTTTAAGGGAAG
GCATGAGCCAATCCAACAACCCCAGCAAAGAAGAACTGGATTTAATCATCACTAACGCTTTAATCGTGGATTACACCGGT
ATTTATAAAGCGGATATTGGTATTAAAGACGGCAAAATCGCAGGCATTGGTAAAGGCGGTAACAAAGACATGCAAGATGG
CGTTAAAAACAATCTTAGCGTGGGTCCTGCTACTGAAGCCTTAGCCGGTGAAGGTTTGATCGTAACTGCTGGTGGTATTG
ACACACACATCCACTTCATCTCCCCCCAACAAATCCCTACAGCTTTTGCAAGCGGTGTAACAACCATGATTGGTGGCGGA
ACTGGCCCTGCTGATGGCACTAACGCAACCACTATCACTCCAGGCAGAAGAAATTTAAAATGGATGCTCAGAGCGGCTGA
AGAATATTCTATGAACTTAGGTTTCTTAGCTAAAGGTAACACTTCTAACGATGCAAGCTTAGCCGATCAAATTGAAGCCG
GTGCGATTGGTTTTAAAATCCACGAAGACTGGGGAACAACTCCTTCTGCAATCAACCATGCGTTAGATGTTGCGGACAAA
TACGATGTGCAAGTCGCTATCCACACAGACACTTTGAATGAAGCCGGTTGTGTAGAAGACACTATGGCAGCCATTGCCGG
ACGCACTATGCACACTTTCCACACTGAAGGTGCTGGCGGCGGACACGCTCCTGATATTATTAAAGTGGCCGGTGAACACA
ACATTCTGCCCGCTTCCACTAACCCCACTATCCCTTTCACTGTGAATACAGAAGCAGAACACATGGACATGCTTATGGTG
TGCCACCACTTGGATAAAAGCATTAAAGAAGATGTTCAGTTCGCTGATTCAAGGATCCGCCCTCAAACCATTGCGGCTGA
AGACACTTTGCATGACATGGGGATTTTCTCAATCACTAGTTCTGACTCTCAAGCTATGGGCCGTGTGGGTGAAGTTATCA
CTAGAACTTGGCAAACAGCTGACAAAAACAAAAAAGAATTTGGCCGCTTGAAAGAAGAAAAAGGCGATAACGACAACTTC
AGGATCAAACGCTACTTGTCTAAATACACCATTAACCCAGCGATCGCTCATGGGATTAGCGAGTATGTAGGTTCTGTAGA
AGTGGGCAAAGTGGCTGACTTGGTATTGTGGAGTCCCGCATTCTTTGGCGTGAAACCCAACATGATCATCAAAGGCGGGT
TCATTGCATTGAGTCAAATGGGTGATGCGAACGCTTCTATCCCTACCCCACAACCGGTTTATTACAGAGAAATGTTCGCT
CATCATGGTAAAGCCAAATACGATGCCAACATCACTTTTGTGTCTCAAGCAGCTTATGACAAAGGCATTAAAGAAGAATT
AGGGCTTGAAAGACAAGTGTTGCCGGTAAAAAATTGCAGAAATATCACTAAAAAAGACATGCAATTCAACGACACTACCG
CTCACATTGAAGTCAATCCTGAAACTTACCATGTGTTCGTGGATGGCAAAGAAGTAACTTCTAAACCAGCCAATAAAGTG
AGCTTGGCGCAACTCTTTAGCATTTTCTAG

Protein sequence :
MKKISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTG
IYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLAKGNTSNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKV
SLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 4e-157 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 4e-157 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-146 59
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-146 59
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-146 59
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-146 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_005786268.1 urease subunit beta VFG0270 Protein 0.0 99