Gene Information

Name : HPSNT_02820 (HPSNT_02820)
Accession : YP_005786704.1
Strain : Helicobacter pylori Santal49
Genome accession: NC_017376
Putative virulence/resistance : Virulence
Product : cytotoxin-associated protein A
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 571829 - 575386 bp
Length : 3558 bp
Strand : +
Note : -

DNA sequence : 
ATGACTAACGAAACCATTGATCAAACAACAACACCAGATCAAACACCAAACCAAACGGCTTTTAACCCGCAGCAATTTAT
CAATAATCTTCAAGTAGCTTTTCTTAAAGTTGATAACGCTGTCGCTTCATACGATCCTGATCAAAAACCAATCGTTGATA
AGAACGATAGGGATAACAGGCAAGCTTTTGATGGAATCTCGCAATTAAGGGAAGAATACTCCAATAAGGCGATCAAAAAT
CCTACCAAAAAGAATCAGTATTTTTCAGACTTTATCAATAAGAGCAATGATTTAATCAACAAAGACGCTCTCATTGATGT
AGAATCTTCCACAAAGAGCTTTCAGAAATTTGGGGATCAGCGTTACCGAATTTTCACAAGTTGGGTGTCCCATCAAAACG
ATCCGTCTAAAATCAACACCCGATCGATCCGAAATTTTATGGAAAATATCATACAACCCCCTATCTCTGATGATAAAGAA
AAAGCAGAGTTTTTGAAATCCGCCAAACAATCTTTTGCAGGAATCATTATAGGGAATCAAATCCGAACGGATCAAAAGTT
CATGGGCGTGTTTGATGAATCCTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGAGCCTACTGGTGGGGATTGGTTGG
ATATTTTTCTCTCATTTATATTTGACAAAAAACAATCTTCTGATGTCAAAGAAGCAATCAATCAAGAACCAGTTCCCCAT
GTCCAACCAGATATAGCCACTACCACCACCCACATACAAGGCTTACCGCCTGAATCTAGGGATTTGCTTGATGAAAGGGG
TAATTTTTCTAAATTCACTCTTGGCGATATGGAAATGTTAGATGTTGAGGGAGTCGCTGACATTGATCCCAATTACAAGT
TCAATCAATTATTGATTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAACCTGAAAAAGTT
TCATTATTGTATGCGGGCAATGGTGGTTTTGGAGCCAAGCACGATTGGAACGCCACCGTTGGTTATAAAGACCAACAAGG
TAACAATGTGGCTACAATAATTAATGTGCATATGAAAAACGGCAGTGGCTTAGTCATAGCGGGTGGTGAGAAAGGGATTA
ACAACCCTAGTTTTTATCTCTACAAAGAAGACCAACTCACAGGCTCACAACGAGCATTGAGTCAAGAAGAGATCCGAAAC
AAAATAGATTTCATGGAATTTCTTGCACAAAATAATGCTAAATTAGACAACTTGAGCGAGAAAGAGAAGGAAAAATTCCG
AAATGAGATTAAAGATTTCCAAAAAGACTCTAAGGCTTATTTAGACGCCCTAGGGAATGATCGTATTGCTTTTGTTTCTA
AAAAAGACACAAAACATTCAGCTTTAATTACTGAGTTTGGTAATGGGGATTTGAGCTACACTCTCAAAGATTATGGGAAA
AAAGCAGATAAAGCTTTAGATAGGGAGACAAAAACCACTCTTCAAGGTAGCCTAAAACATGATGGCGTGATGTTTGTTGA
TTATTCTAATTTCAAATACACCAACGCCTCCAAGAATCCCAATAAGGGTGTAGGCGTTACGAATGGCGTTTCCCATTTAG
AAGCAGGCTTTGACAAGGTAGCTGTCTTTAATTTGTCTAATTTGAATAATCTCACTATCACTAGTTTTATAAGGCAGGAT
TTAGAGGATAAACTAGTCGCTAAAGGATTGTCCCCACAAGAAGCCAATAAGCTCATCAAAGACTTTTTGAGCAACAACAA
AGAATTGGTTGGAAAAGTTTCAAACTTCAATAAAGCTGTAGCTGAAGCTAAAAACACGGGCAATTATGACGAAGTGAAAA
AAGCTCAGAAAGATCTTGAAAAATCTCTAAGGAAACGAGAGCATTTGGAGAAAGAGGTAGCGAAAAATTTGGAGAGCAAA
AGCGGCAACAAAAATAAAATGGAAGCGAAATCTCAAGCTAACAGCCAAAAAGATGAGATTTTTGCGTTGATTAATAAAGA
GGCTACTAGGGAAGCAAGAGCGGCTGCTTACGCTTCGAATCTTAAAGGCATCAAAAGGGAATTGTCTGATAAACTTGAAA
ATATCAACAAGAATTTGAAAGGCTTTGATAAATCTTTTGATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGCA
GAAGAAACACTAAAAGCCCTTAAAGGCTCGGTGAAAGATTTAGGTATCAATCCAGAATGGATTTCAAAAGTTGAAAACCT
TAATGCAGCTTTGAATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACGCAAGCCAAAAACGACCTTGAAA
ATTCCGTTAAAGATGTGATCATCAATCAAAAGATAACGGATAAAGTTGATAATCTCAATCAAGCGGTATCAGTGGCTAAA
GTAACGGGCGATTTCAGTAGTGTAGAGCAAGCGTTAGCCGATCTCAAAAATTTCTCAAAGGAGCAATTGGCTCAACAAGC
TCAAAAAAATGAAGATTTCAATACTGGAAAAAATTCTGCACTATACCAATCCGTTAAGAATGGTGTGAATGGAACCCTAG
TCGGTAATGGGCTATCTAAAGCAGAAGCCACAACTCTTTCTAAAAATTTTTCAGATATCAAGAAAGAGTTGAATGCAAAA
CTTGGAAATTTCAATAACAATAACAATAATGGTCTCAAAAACGAACCCATTTATGCTAAAGTTAATAAAAAGAAAGCAGG
GCAAGCAGCTAGCCTTGAAGAACCCATTTACGCTCAAGTTGCTAAAAAGGTAAATGCAAAAATTGACCAACTCAATCAAG
CAGCAAGTGGTTTGGGTGGTGTAGGGCAAGCAGCGGGCATCCCTTTGAAAAGGCATGATAAAGTTGATGATCTCAGTAAG
GTAGGGCTTTCAGCTAGCCCTGAACCCATTTATGCTACGATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAGGCATGA
TAAAGTTGATGATCTCAGTAAGGTAGGGCTTTCAAGGAATCAAGAATTGGCTCAGAAAATTGACAATCTCAATCAAGCGG
TATCAGAAGCTAAAGCAGGTTTTTTTGGCAATCTAGAGCAAACGATAGACAAGCTCAAAGATTCTACAAAACACAATCCC
ATGAATCTATGGGTTGAAAGTGCAAAAAAAGTACCTGCTAGTTTGTCAGCGAAATTAGACAATTACGCTACTAACAGCCA
CACACGCATTAATAGCAATATCAAAAATGGAGCAATCAATGAAAAAGCGACCGGTATGCTAACGCAAAAAAACCCTGAGT
GGCTTAAGCTCGTGAATGATAAGATAGTTGCGCATAATGTGGGAAGCGTTCCTTTGTCAGAGTATGATAAAATTGGCTTC
AACCAGAAGAATATGAAAGATTATTCTGATTCGTTCAAGTTTTCCACCAAGTTGAACAATGCCGCAAAAGACATTAAGTC
TGGCTTTACGCAATTTTTAGCCAATGCATTTTCTACAGGATATTACTGCTTGGCGGGGGAAAATGCAGAGCATGGAATCA
AAAATGTTAATACAAAAGGTGGTTTCCAAAAATCTTAA

Protein sequence : 
MTNETIDQTTTPDQTPNQTAFNPQQFINNLQVAFLKVDNAVASYDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKN
PTKKNQYFSDFINKSNDLINKDALIDVESSTKSFQKFGDQRYRIFTSWVSHQNDPSKINTRSIRNFMENIIQPPISDDKE
KAEFLKSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKNGEPTGGDWLDIFLSFIFDKKQSSDVKEAINQEPVPH
VQPDIATTTTHIQGLPPESRDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKV
SLLYAGNGGFGAKHDWNATVGYKDQQGNNVATIINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIRN
KIDFMEFLAQNNAKLDNLSEKEKEKFRNEIKDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFGNGDLSYTLKDYGK
KADKALDRETKTTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGVTNGVSHLEAGFDKVAVFNLSNLNNLTITSFIRQD
LEDKLVAKGLSPQEANKLIKDFLSNNKELVGKVSNFNKAVAEAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVAKNLESK
SGNKNKMEAKSQANSQKDEIFALINKEATREARAAAYASNLKGIKRELSDKLENINKNLKGFDKSFDEFKNGKNKDFSKA
EETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKNDLENSVKDVIINQKITDKVDNLNQAVSVAK
VTGDFSSVEQALADLKNFSKEQLAQQAQKNEDFNTGKNSALYQSVKNGVNGTLVGNGLSKAEATTLSKNFSDIKKELNAK
LGNFNNNNNNGLKNEPIYAKVNKKKAGQAASLEEPIYAQVAKKVNAKIDQLNQAASGLGGVGQAAGIPLKRHDKVDDLSK
VGLSASPEPIYATIDDLGGPFPLKRHDKVDDLSKVGLSRNQELAQKIDNLNQAVSEAKAGFFGNLEQTIDKLKDSTKHNP
MNLWVESAKKVPASLSAKLDNYATNSHTRINSNIKNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGF
NQKNMKDYSDSFKFSTKLNNAAKDIKSGFTQFLANAFSTGYYCLAGENAEHGIKNVNTKGGFQKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0547 BAD14045.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 94
cagA AAR03881.1 CagA Virulence cag PAI Protein 0.0 94
cagA AAR03970.1 CagA Virulence cag PAI Protein 0.0 93
cagA AAC44706.1 CagA Virulence cag PAI Protein 0.0 92
HP0547 NP_207343.1 cag pathogenicity island protein (cag26) Virulence cag PAI Protein 0.0 92
cagA AAR03909.1 CagA Virulence cag PAI Protein 0.0 92
cagA AAF17598.1 CagA Virulence cag PAI Protein 0.0 92
cagA BAD51747.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 90
cagA BAC10428.1 CagA Virulence cag PAI Protein 0.0 88
HP0547 BAD13908.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 88
cagA BAD51750.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 87
cagA BAD51760.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 87
cagA BAD51758.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 87
cagA AAR03939.1 CagA Virulence cag PAI Protein 0.0 87
cagA NP_223213.1 cag island protein, cytotoxicity associated immunodominant antigen Virulence cag PAI Protein 0.0 86
cagA BAD51761.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA BAD51756.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA BAD51751.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 86
cagA BAC10432.1 CagA Virulence cag PAI Protein 0.0 86
HP0547 BAD13990.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 86
cagA BAD51766.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAD51752.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAD51753.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA YP_003728762.1 cytotoxin-associated protein A Virulence cag PAI Protein 0.0 85
cagA BAC10429.1 CagA Virulence cag PAI Protein 0.0 85
HP0547 BAD13935.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 85
cagA AGC69806.1 cag pathogenicity island protein A Virulence cag PAI Protein 0.0 85
cagA BAD51759.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51764.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 83
cagA YP_005774524.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 81
cagA BAC10419.1 CagA Virulence cag PAI Protein 0.0 81
cagA BAD51749.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 80
cagA BAD51762.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 80
cagA BAC10433.1 CagA Virulence cag PAI Protein 0.0 80
HP0547 BAD14018.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 80
cagA BAC10426.1 CagA Virulence cag PAI Protein 0.0 80
cagA BAC10431.1 CagA Virulence cag PAI Protein 0.0 80
HP0547 BAD13963.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 80
cagA BAC10420.1 CagA Virulence cag PAI Protein 0.0 80
cagA BAC10435.1 CagA Virulence cag PAI Protein 0.0 80
HP0547 BAD14072.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 80
cagA BAD51755.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 80
cagA BAD51754.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 80
cagA YP_005777288.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
cagA BAC10421.1 CagA Virulence cag PAI Protein 0.0 79
HP0547 BAD13799.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
cagA YP_005779046.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
HP0547 BAD13880.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
cagA AAF17597.1 CagA Virulence cag PAI Protein 0.0 79
cagA BAD51744.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 79
cagA YP_005775747.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 79
HP0547 BAD13853.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 76
cagA BAC10427.1 CagA Virulence cag PAI Protein 0.0 76
cagA BAC10423.1 CagA Virulence cag PAI Protein 0.0 70
cagA BAC10430.1 CagA Virulence cag PAI Protein 0.0 69
HP0547 BAD13826.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 69
cagA BAC10424.1 CagA Virulence cag PAI Protein 0.0 69
cagA BAC10422.1 CagA Virulence cag PAI Protein 0.0 69

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPSNT_02820 YP_005786704.1 cytotoxin-associated protein A VFG0306 Protein 0.0 92