Gene Information

Name : guaA (HPSNT_05175)
Accession : YP_005787155.1
Strain : Helicobacter pylori Santal49
Genome accession: NC_017376
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1060093 - 1061619 bp
Length : 1527 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACACAGCTGATTGCTAGAAGATTGAGAGAGAGCGGGATTTATACAGA
AATAGTCCCTTTTTTTGAAAGCATAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGTGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCTAATGGGAAAATCTTTGATTTAAATGTGCCGATTTTAGGGATTTGCTACGGC
ATGCAGTATTTGGTGGATTTTTTTGGGGGGGTAGTGGTTGGTGCGAATGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CACTCAAGATTCTGTGATTTTTGAAGGCGTGAAGATTAAAAGCCTTGTGTGGATGAGCCATATGGATAAAGTCATAGAAT
TGCCTAAAGGCTTCACTACCCTTGCAAAAAGCCCTAATTCGCCCCATTGCGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAGGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTGGTTTGTGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATAACGCGATTGAAAGAAAAAATTGCTAACGCTAAGGTTTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTGCACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGCTTGTTGCGTAAAAATGAAAAAGAAAGGGTGCAAGCGATGTTTAAAGACTTGCAAATCCCTTTAAA
CACGATAGACGCTAAAGGAATCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAGCGAAAAATCATCGGTG
AAACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAGAAGCACCATTTAAAAGGCAAAATTGAGTTTTTAGCCCAAGGCACT
TTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACCCACCATAATGTGGGCGGACT
GCCTGAATGGATGGACTTTAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGCGCGTTTGTTGGGTAAGGAAT
TGGGCGTTAGCCAAGATTTTTTAATGCACCACCCCTTTCCAGGGCCTGGGCTTGCTGTAAGGATTTTAGGCGAAGTCAGT
GAGAGTAAAATCAAACGCTTGCAAGAAGCGGATTTTATTTTTATAGAAGAGCTTAAAAAAGCCAATTTGTATGACAAGGT
TTGGCAAGCTTTTTGCGTGCTGTTAAATGTCAATTCTGTGGGGGTTATGGGGGATAACCGCACTTATGAAAACGCCATTT
GCTTAAGAGCGGTAAATGCGAGCGATGGCATGACAGCGAGCTTTTCATTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGCATTACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGATATTACTTCTAAGCCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYTEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPNGKIFDLNVPILGICYG
MQYLVDFFGGVVVGANEQEFGKAVLEITQDSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENGKIFGL
QFHPEVIQSEEGGKILENFALLVCGCEKTWGMQHFAQREITRLKEKIANAKVLCAVSGGVDSTVVATLLHRAIKDNLIAV
FVDHGLLRKNEKERVQAMFKDLQIPLNTIDAKGIFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEARLLGKELGVSQDFLMHHPFPGPGLAVRILGEVS
ESKIKRLQEADFIFIEELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-132 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-132 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-132 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-114 47