Gene Information

Name : metC (HMPREF0462_0161)
Accession : YP_005784728.1
Strain : Helicobacter pylori 83
Genome accession: NC_017375
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.8
Position : 150886 - 152028 bp
Length : 1143 bp
Strand : -
Note : COG: COG0626; Pfam: PF01053; InterPro: IPR000277

DNA sequence : 
ATGCGCATGCAAACAAAATTAATCCATGGGGGTATTAGTGAGGACGCAACAACCGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCGTCATAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAACTCATCGCCGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCCTCTGGACTAGCTGGGATCCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGCTATTGGGCGATGATGTTTATGGGGGGACTTTTCGCTTGTTCAATAA
AGTGCTTGTCAAAAACGACCTTTCTTGCACCATTATAGACACTAGCGATATATCCCAGATCAAAAAGGCTATCAAGCCCA
ACACCAAAGCCCTTTATTTGGAAACTCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGTGCTAGTGTCGCT
AAAGATCATGGTTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGAGCGGA
TATTGTGGTGCATAGCGGCACCAAATACTTGGGCGGTCATAGCGATGTGGTCGCTGGGCTTGTAACCACTAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA
GGGATTAAAACGCTAGGATTGCGCATGGAGGCCCACCAAAAAAATGCCCTTTGCGTGGCTGAGTTTTTAGAAAAACACCC
TAAAGTAGAAAAGGTTTATTACCCGGGCTTGAGCACTCACCCTAACCACGAGCTGGCCAAAAAACAGATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACTCTCAAAAACGACAGCGAGGCGGTTGCTTTTGTGGAAAGCCTTAAACTATTCATTTTGGGC
GAGAGTTTGGGCGGGGTGGAAAGTTTGGTGGGAATTCCTGCATTCATGACCCATGCGTGTATCCCCAAAGCGCAACGAGA
AGCTGCCGGGATTAGAGATGGCCTGGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC
AAGCGTTCGCTAAAATAGGCTAA

Protein sequence : 
MRMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNDLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA
KDHGLLTIVDNTFATPYCQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLSTHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFILG
ESLGGVESLVGIPAFMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-97 54
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-98 54
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-74 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_005784728.1 cystathionine beta-lyase BAC0207 Protein 8e-62 43