Gene Information

Name : fliI (HMPREF0462_1399)
Accession : YP_005785965.1
Strain : Helicobacter pylori 83
Genome accession: NC_017375
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 1395991 - 1397295 bp
Length : 1305 bp
Strand : -
Note : COG: COG1157; Pfam: PF00006; InterPro: IPR005714

DNA sequence :
ATGCCCCTAAAATCCTTAAAAAACCGCTTGAATCAGCATTTTGATCTATCGCCTCGCTACGGGAGCGTGAAAAAAATCAT
GCCCAATATCGTTTATGCGGATGGTTTTAACCCGTCTGTGGGCGATGTGGTGAAGATTGAAAAAAGCGATGGCACTGAAT
GCATGGGAATGGTGGTGGTGGCAGAAAAAGAGCAGTTTGGTTTCACGCCCTTTAATTTTATAGAGGGGGCTAGGGCTGGC
GATAAGGTGCTGTTTTTAAAAGAGGGGTTGAATTTCCCTGTGGGCCGTAATCTTTTAGGGAGGGTGCTTAACCCTTTAGG
GCAAGTCATTGACAATAAGGGGGCGCTAGATTATGAGCGGTTAGCGCCTGTGATTACAACGCCTATAGCCCCTTTAAAAA
GAGGCTTGATTGATGAGGTTTTTAGCGTGGGGGTGAAGAGCATTGATGGGCTTTTGACTTGCGGTAAGGGACAAAAACTG
GGCATTTTTGCCGGATCTGGGGTGGGTAAATCCACGCTAATGGGCATGATCACTAGGGGTTGCTTAGCGCCTATTAAAGT
GATCGCTTTGATTGGGGAAAGGGGCAGAGAAATCCCTGAATTTATAGAGAAAAACTTAAAAGGGGATTTAAGCTCTTGCG
TGTTGGTAGTCGCTACGAGCGATGATAGCCCTTTGATGCGCAAATACGGGGCCTTTTGCGCGATGAGCGTGGCGGAGTAT
TTTAAAAACCAGGGGCTAGATGTGTTGTTTATTATGGATTCAGTGACTCGTTTCGCTATGGCTCAAAGAGAGATTGGCTT
AGCCTTAGGCGAACCACCCACTTCCAAAGGCTACCCCCCATCCGCGCTTTCCTTATTGCCTCAATTAATGGAGAGAGCGG
GCAAGGAAGAAAATAAGGGGAGCATTACGGCTTTTTTTAGCGTGCTGGTAGAGGGCGATGATTTGAGCGATCCCATAGCC
GATCAGGCCAGGAGTATTTTAGACGGGCATATTGTCTTAAGCAGGGAATTAACCGATTATGGGATCTACCCGCCTATTAA
TATTTTAAACTCCGCATCAAGGGTGGCTAAAGACATCATCAGCGAGTCTCAAAACCTTCATGCGAGAAAATTCCGCCGTT
TGTATGCGTTATTGAAAGAAAATGAAATGCTCATTCGCATCGGCTCTTATCAAATGGGGAACGATAAAGAGCTTGATGAA
GCGATTAAGAAAAAGGCTTTAATGGAGCAATTTTTAGCGCAAGATGAAAACGCTTTACAGCCTTTTGAAACAAGTTTTCA
GCAATTAGAAGAAATCTTAAGATAA

Protein sequence :
MPLKSLKNRLNQHFDLSPRYGSVKKIMPNIVYADGFNPSVGDVVKIEKSDGTECMGMVVVAEKEQFGFTPFNFIEGARAG
DKVLFLKEGLNFPVGRNLLGRVLNPLGQVIDNKGALDYERLAPVITTPIAPLKRGLIDEVFSVGVKSIDGLLTCGKGQKL
GIFAGSGVGKSTLMGMITRGCLAPIKVIALIGERGREIPEFIEKNLKGDLSSCVLVVATSDDSPLMRKYGAFCAMSVAEY
FKNQGLDVLFIMDSVTRFAMAQREIGLALGEPPTSKGYPPSALSLLPQLMERAGKEENKGSITAFFSVLVEGDDLSDPIA
DQARSILDGHIVLSRELTDYGIYPPINILNSASRVAKDIISESQNLHARKFRRLYALLKENEMLIRIGSYQMGNDKELDE
AIKKKALMEQFLAQDENALQPFETSFQQLEEILR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-73 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 4e-77 46
escN AAC38383.1 EscN Virulence LEE Protein 2e-78 46
escN AAC31513.1 L0034 Virulence LEE Protein 1e-78 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-78 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-78 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-78 46
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-77 45
escN AAL57542.1 EscN Virulence LEE Protein 9e-77 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 5e-77 45
escN AAK26715.1 EscN Virulence LEE Protein 9e-77 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 5e-54 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-54 45
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-79 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-79 44
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-82 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-81 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-81 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-81 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-80 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-81 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-80 44
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-69 44
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-69 44
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-53 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 5e-53 44
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-78 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 5e-59 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-59 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-59 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-58 42
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-73 41
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-77 41
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-77 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-53 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_005785965.1 flagellar protein export ATPase FliI VFG0390 Protein 5e-79 52
fliI YP_005785965.1 flagellar protein export ATPase FliI VFG0192 Protein 2e-76 51
fliI YP_005785965.1 flagellar protein export ATPase FliI VFG0048 Protein 1e-78 50
fliI YP_005785965.1 flagellar protein export ATPase FliI VFG2331 Protein 1e-71 49
fliI YP_005785965.1 flagellar protein export ATPase FliI VFG2144 Protein 1e-77 47
fliI YP_005785965.1 flagellar protein export ATPase FliI VFG0730 Protein 1e-78 46
fliI YP_005785965.1 flagellar protein export ATPase FliI VFG0812 Protein 8e-79 46
fliI YP_005785965.1 flagellar protein export ATPase FliI VFG1254 Protein 2e-77 45
fliI YP_005785965.1 flagellar protein export ATPase FliI VFG1778 Protein 3e-56 42