Gene Information

Name : guaA (HMPREF0462_1056)
Accession : YP_005785622.1
Strain : Helicobacter pylori 83
Genome accession: NC_017375
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1058138 - 1059664 bp
Length : 1527 bp
Strand : -
Note : COG: COG0519; Pfam: PF00117,PF03054,PF00958; InterPro: IPR001674

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACACAGCTGATTGCTAGAAGATTGAGAGAGAGCGGGATTTATACAGA
AATAGTCCCTTTTTTTGAAAGCATAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGTGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCTAGCGAGAAAATCTTTGATTTGAATGTGCCGATTTTAGGGATTTGCTACGGC
ATGCAGTATTTGGTGGATTTTTTTGGGGGGGTAGTGGTTGGTGCGAATGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CACTCAAGATTCTGTGATTTTTGAAGGCGTGAAAACCAAAAGCCTTGTGTGGATGAGCCATATGGATAAAGTCATAGAAT
TGCCTAAAGGCTTCACTACTCTTGCAAAAAGCCCTAATTCCCCCCATTGCGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAGGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTAGTTTGTGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATGGTGCGCTTGAAAGAAAAAATTGCTAACGCTAAGGTTTTGT
GCGCAGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTACACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGCTTGTTGCGTAAAAATGAAAAAGAAAGGGTGCAAGCGATGTTTAAAGACTTGCAAATCCCTTTAAA
CACGATAGACGCTAAAGAAATCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AAACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAGAAGCACCATTTAAAAGGCAAAATTGAGTTTTTAGCCCAAGGCACT
TTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACCCACCATAATGTGGGCGGACT
GCCTGAATGGATGGACTTTAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGCGCGTTTGTTGGGTAAGGAAT
TGGGCGTTAGCCAGGATTTTTTGATGCGCCACCCCTTTCCAGGGCCTGGGCTTGCGGTAAGGATTTTAGGCGAAGTCAGC
GAGAGTAAGATCAGATGCTTGCAAGAAGCGGATTTTATTTTTATAGAAGAGCTTAAAAAGGCCAATTTGTATGACAAGGT
TTGGCAGGCTTTTTGCGTGCTATTGAATGTCAATTCTGTGGGGGTTATGGGGGATAATCGCACTTATGAAAACGCTATTT
GTTTAAGAGCGGTGAATGCGAGCGATGGCATGACAGCGAGCTTTTCATTTTTGGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGTATCACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGATATTACTTCTAAGCCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYTEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPSEKIFDLNVPILGICYG
MQYLVDFFGGVVVGANEQEFGKAVLEITQDSVIFEGVKTKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENGKIFGL
QFHPEVIQSEEGGKILENFALLVCGCEKTWGMQHFAQREMVRLKEKIANAKVLCAVSGGVDSTVVATLLHRAIKDNLIAV
FVDHGLLRKNEKERVQAMFKDLQIPLNTIDAKEIFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEARLLGKELGVSQDFLMRHPFPGPGLAVRILGEVS
ESKIRCLQEADFIFIEELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 9e-133 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-133 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-114 47