Gene Information

Name : metB (hp2017_0112)
Accession : YP_005783088.1
Strain : Helicobacter pylori 2017
Genome accession: NC_017374
Putative virulence/resistance : Resistance
Product : Cystathionine gamma-synthase/ cystathione beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.1
Position : 108119 - 109255 bp
Length : 1137 bp
Strand : -
Note : -

DNA sequence :
ATGCAAACCAAATTAATCCATGGGGGCATTAGTGAGGATGCGACAACGGGGGCGGTGAGCGTGCCTATTTATCAGGCTTC
CACCTACCGCCAAGACGCCATAGGCCGCCACAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTGCTTTAG
AAGAGCTCATCGCTGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCCTCTGGTTTAGCCGGAATCCACGCTGTCTTT
TCCCTCTTGCAATCAGGCGATCATGTGTTATTGGGCGATGATGTCTATGGGGGGACTTTCCGCTTGTTTAATAAGGTGCT
TGTCAAAAACGGGCTTTCTTGCACCATTATAGACACTAGCGACATATCCCAAATTAAAAAGGCTATCAAGCCCAACACCA
AAGCCCTTTATTTAGAGACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGCGCTAGTGTCGCTAAAGAT
CATGGTTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGGGCGGATATTGT
GGCGCATAGCGGCACAAAATACTTAGGCGGGCATAGCGATGTGGTTGCTGGGCTTGTAACCACTAATAATGAAGCGCTAG
CCCAAGAGATCGCTTTTTTTCAAAATGCTATCGGTGGGGTGCTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGAGGGATT
AAAACGCTGGGATTGCGCATGGAGGCCCATCAAAAAAACGCCCTTTGCGTGGCTGAATTTTTAGAAAAACACCCTAAAGT
GGAAAGGGTTTATTACCCGGGTTTGCCCACTCACCCTAACCACGAGCTAGCCAAAGCCCAAATGCGTGGCTTTAGTGGGA
TGCTCTCTTTCACCCTTAAAAATGACAGCGAGGCGGCTCTTTTTGTAGAAAGCCTTAAATTATTCATTTTAGGCGAGAGT
TTGGGCGGAGTGGAAAGCTTGGTAGGGATTCCAGCGCTAATGACCCATGCATGTATCCCTAAAGAACAACGAGAAGCTGC
TGGAATCAGAGATGGTTTGGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATTTGCTAGAAGATTTAGAGCAAGCGT
TCGCTAAAATAAGCTAA

Protein sequence :
MQTKLIHGGISEDATTGAVSVPIYQASTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHAVF
SLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKD
HGLLTIVDNTFATPYCQNPLLLGADIVAHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQRGI
KTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNHELAKAQMRGFSGMLSFTLKNDSEAALFVESLKLFILGES
LGGVESLVGIPALMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-99 55
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-97 55
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-71 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_005783088.1 Cystathionine gamma-synthase/ cystathione beta-lyase BAC0207 Protein 1e-61 43