Gene Information

Name : HPIN_04280 (HPIN_04280)
Accession : YP_005782165.1
Strain : Helicobacter pylori India7
Genome accession: NC_017372
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein Beta
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 869094 - 871340 bp
Length : 2247 bp
Strand : +
Note : COG3505 Type IV secretory pathway, VirD4 components

DNA sequence :
ATGGAAGACTTTTTGTATAACACCTTATATTTCATAGAAGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTATTTTTTCTTTACAAATTCATAAAAGCTCAAAAAAAGGCTTTTAAAGATAAAGCTAACCAACCTCAAAAGAAAA
AAAGCTTTAAAGAAATCATTATAGATGGGCTGAAAGAAAGAGTTAAAACCTTTGGCTTTTGGTTACAAGCTATACTCTTA
CTATCTTATTCTTTTATCACATCAGGGTTACTTTTTTTGATTCTCTTAGGTAATTTTTATGATGATAACAGATTGCCTGA
GAGCGATGATGATCTTTTTGATATATGGATCTATGCTATACAAGATTTTCCTGCATACTATTTTAAGGCGCTTTGTTTTA
GTCCACTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATCTTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGACATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGGAGTGC
GAGTTGGGAAACTGAAGAGAAAATGATCAAAGCTAAACTTATCACACCCAATAATAAAAAACGCGCCTTTGACAAACGAG
AGGTTATTGTAGGCAGGCGTGGTTTAGGGGATTTTATCGCTTACGCAGGACAGGCGTTCATTGGCTTGATTGCTCCTACT
AGAAGCGGTAAAGGTGTGGGTTTCATCATGCCCAATATGATCAATTATCCTCAAAATATCGTTGTGTTTGACCCTAAGGC
GGACACTATGGAAACTTGCGGAAAAATCAGAGAAAAACGCTTCAACCAAAAAGTGTTCATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTGACTGAAGACATACTCTCTCAAATT
GACACACGCCTAAAAGGGCATGGGATGGTGGCTAGTGGGGGGGATTTTTCCACTCAAATCTTTGGATTGGCTAAGCTCGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTTTTTAGCAATCAAGCACGGAATCTTTTTGTCATCAATTGCAATATTT
ATAGGGATCTCATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACCCCCACGATG
TTTTTCATAGGTTCTATGGCAAGCGGTATCAACTTGATTGATGAAGACACAAACATGGAAAAAGTCGTGTCTCTGATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGACAATCTAAGAGCGCTTAGTCCTGCTACTAGAAACATGTGGAATAACT
TCAAGACAATGGGTGGCGCTAAAGAAACTTATAGCTCTGTTCAAGGGGTCTATACATCAGCGTTTGCGCCCTACAATAAC
GCCATGATCAGAAATTTCACGAGCGCTAATGATTTTGATTTCAGGCGTTTAAGGATTGATGAAGTGAGTATTGGCGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGGCCGATACTAGAGCTGTTTTTCAATGTGATGATTTATAGCAATCTTATTC
TGCCAATCCATGATCCACAATGCAAAAGAAGTTGCTTAATGCTTATGGATGAATTCACGCTCTGTGGCTATTTGGAAACC
TTTGTTAAAGCGGTAGGGATCATGGCAGAATACAACATGCGCCCCGCTTTTGTGTTTCAAAGTAAGGCGCAACTAGAGAA
TGACCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTGAATATGTATTATGGGATTA
ACAACGATAACTACTATGAACATTTTGAAAAACTTTCTAAGGTGTTAGGGAAATACACAAGGCAAGACGTGAGCCGAAGC
ATTGATGATAATACAGGTAAGACCAATACTTCCATCAGCAACAAAGAGCGGTTTTTGATGACCCCTGATGAATTGATGAC
TATGGGCGATGAGCTTATCATTCTAGAGAATACGCTCAAACCCATCAAATGCCACAAGGCACTTTACTATGATGATCCAT
TCTTCACCGATGAACTCATCAAGGTGAGTGAAAGCTTGAGCAAGAAATACAAATTGGGGAAAGTGCCCAATCAGGCAACA
TTCTATGATGATTTGCAGGCCGCTAAAACTAAAGGCGAATTGAGCTATGATAAATCTTTAGTGCCTGTGGGTTCAAGCGA
ACTGTGA

Protein sequence :
MEDFLYNTLYFIEDYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKSFKEIIIDGLKERVKTFGFWLQAILL
LSYSFITSGLLFLILLGNFYDDNRLPESDDDLFDIWIYAIQDFPAYYFKALCFSPLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWETEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVFIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDEDTNMEKVVSLMEFFGGEEDKSGDNLRALSPATRNMWNNFKTMGGAKETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSESLSKKYKLGKVPNQAT
FYDDLQAAKTKGELSYDKSLVPVGSSEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cag5 AAR03858.1 Cag5 Virulence cag PAI Protein 0.0 99
cag-beta AAF80195.1 Cag-beta Virulence cag PAI Protein 0.0 99
virD4 NP_223191.1 cag island protein, DNA transfer protein Virulence cag PAI Protein 0.0 99
HP0524 BAD14023.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13776.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_003728740.1 cag pathogenicity island protein beta Virulence cag PAI Protein 0.0 99
HP0524 BAD13803.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03916.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13830.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 NP_207320.1 cag pathogenicity island protein (cag5) Virulence cag PAI Protein 0.0 99
HP0524 BAD13967.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13912.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005775727.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13995.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13857.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03887.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13885.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005779066.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03947.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD14049.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005774545.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13940.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
cag5 YP_005777268.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPIN_04280 YP_005782165.1 cag pathogenicity island protein Beta VFG0284 Protein 0.0 99