Gene Information

Name : HPIN_00515 (HPIN_00515)
Accession : YP_005781445.1
Strain : Helicobacter pylori India7
Genome accession: NC_017372
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.8
Position : 105707 - 106849 bp
Length : 1143 bp
Strand : -
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGCGCATGCAAACCAAATTAATCCATGGGGGCATTAGTGAGGATGCGACAACGGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCGCCATAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACACGCTTTG
CTTTAGAAGAACTCATCGCCGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCCTCTGGCTTAGCTGGAATCCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGTTGTTAGGCGATGATGTTTATGGGGGGACTTTCCGCTTGTTCAACAA
AGTGCTTGTCAAAAACGGGCTTTCTTGCACCATTATAGACACTAGCGATCTATCCCAAATCAAAAAGGCTATCAAGCAAA
ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGTGCAATGCGTTAGTGTCGCT
AAAGATCATAATTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGAGCGGA
CATTGTGGTGCACAGCGGCACCAAATACTTAGGCGGGCATAGCGATGTGGTTGCTGGGCTTGTAACCACTAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGTTGTTGCAAAGA
GGGATTAAAACGCTGGGATTGCGCATGGAAGCCCATCAAAAAAACGCCCTTTGTGTGGCTGAGTTTTTAGAAAAACACCC
TAAAGTAGAAAGGGTTTATTACCCGGGCCTTCCCACTCACCCTAACCACGATCTAGCCAAAGCCCAGATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACCCTCAAAAATGACAGCGAAGCGGTTGCTTTTGTAGAAAGCCTTAAACTATTCATTTTAGGC
GAGAGTTTGGGCGGGGTGGAAAGTTTGGTGGGGATTCCGGCATTTATGACCCATGCGTGTATCCCTAAAACACAACGAGA
AGCTGCAGGGATCAGAGATGGTTTAGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATCTGTTAGAAGATTTAGAGC
AAGCGTTCGCTAAAATAGGCTAA

Protein sequence :
MRMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDLSQIKKAIKQNTKALYLETPSNPLLKITDLVQCVSVA
KDHNLLTIVDNTFATPYCQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNHDLAKAQMRGFSGMLSFTLKNDSEAVAFVESLKLFILG
ESLGGVESLVGIPAFMTHACIPKTQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-96 54
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-97 54
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 9e-72 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPIN_00515 YP_005781445.1 cystathionine gamma-synthase BAC0207 Protein 1e-60 42