Gene Information

Name : guaA (HPIN_05145)
Accession : YP_005782320.1
Strain : Helicobacter pylori India7
Genome accession: NC_017372
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1052447 - 1053973 bp
Length : 1527 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACACAGCTGATTGCTAGAAGATTGAGAGAGAGCGGGATTTATACAGA
AATAGTCCCTTTTTTTGAAAGCATAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGTGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCCAACGGCAGAATCTTTGATTTGAATGTGCCGATTTTAGGGATTTGCTACGGC
ATGCAATATTTGGTGGATTTTTTTGGGGGGGTAGTGGTTGGTGCGAACGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CACCCAAGATTCTGTGATTTTTGAAGGCGTGAAAACCAAAAGCCTTGTGTGGATGAGCCATATGGATAAAGTCATAGAAT
TGCCTAAAGGCTTCACTACCCTTGCAAAAAGCCCTAATTCGCCCCATTGCGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAGGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTGGTTTGTGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATAACGCGATTGAAAGAAAAAATTGCTAACGCTAAGGTTTTGT
GCGCAGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTATACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGCTTGTTGCGTAAAAATGAAAAAGAAAAAGTTCAAGCGATGTTTAAAGACTTGCAAATCCCTTTAAA
CACGATAGACGCTAAAGAAATCTTTTTGTCTAAATTAAAGGGCGTGAGTGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AAACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAGAAGCACCATTTAAAAGGCAAAATTGAGTTTTTAGCCCAAGGCACT
TTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAGGTGATCAAAACCCACCATAATGTGGGCGGACT
GCCTGAATGGATGGACTTTAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGTGCGTTTGTTGGGTAAGGAAT
TGGGCGTTAGCCAGGATTTTTTAATGCGCCACCCCTTTCCAGGGCCTGGGCTTGCTGTAAGGATTTTAGGCGAAGTCAGT
GAGAGTAAAATCAAACGCTTGCAAGAAGCGGATTTTATTTTTATAGAGGAACTTAAAAAAGCCAATTTGTATGACAAGGT
TTGGCAAGCTTTTTGCGTGCTGTTAAATGTCAATTCTGTGGGGGTTATGGGGGATAACCGCACTTATGAAAACGCTATTT
GTTTGAGAGCGGTAAATGCGAGCGATGGCATGACAGCGAGCTTTTCATTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGCATCACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGATATTACCTCTAAACCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYTEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPNGRIFDLNVPILGICYG
MQYLVDFFGGVVVGANEQEFGKAVLEITQDSVIFEGVKTKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENGKIFGL
QFHPEVIQSEEGGKILENFALLVCGCEKTWGMQHFAQREITRLKEKIANAKVLCAVSGGVDSTVVATLLYRAIKDNLIAV
FVDHGLLRKNEKEKVQAMFKDLQIPLNTIDAKEIFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGVSQDFLMRHPFPGPGLAVRILGEVS
ESKIKRLQEADFIFIEELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-133 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-133 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-115 47