Gene Information

Name : ureB (HPGAM_00390)
Accession : YP_005779813.1
Strain : Helicobacter pylori Gambia94/24
Genome accession: NC_017371
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 76438 - 78147 bp
Length : 1710 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAGATTAGCAGAAAAGAATATGTTTCTATGTATGGCCCTACCACAGGCGATAAAGTGAGATTGGGCGATACAGA
CTTGATCGCTGAAGTAGAACATGACTACACCATTTATGGCGAAGAGCTTAAATTCGGTGGCGGTAAAACCCTAAGAGAAG
GCATGAGCCAATCCAACAACCCTAGCAAAGAAGAACTGGATTTGATCATCACTAACGCTTTAATCGTGGATTACACCGGT
ATTTATAAAGCGGATATTGGTATTAAAGATGGCAAAATCGCTGGCATTGGTAAAGGCGGTAACAAAGACATGCAAGATGG
CGTTAAAAACAATCTTAGCGTGGGTCCTGCTACTGAAGCGCTAGCTGGTGAAGGCTTGATCGTAACGGCTGGTGGTATTG
ACACACACATCCACTTCATTTCACCCCAACAAATCCCTACAGCTTTTGCAAGCGGTGTAACAACCATGATTGGTGGCGGA
ACCGGTCCTGCTGATGGCACTAATGCGACTACTATCACTCCAGGTAGAAGAAACTTAAAATGGATGCTCAGAGCGGCTGA
AGAATATTCTATGAACTTAGGTTTCTTGGCTAAAGGTAACACTTCTAACGATGCGAGCTTAGCGGATCAAATTGAAGCCG
GTGCGATTGGCTTTAAAATCCACGAAGACTGGGGCACCACTCCTTCTGCAATCAATCATGCGTTAGACGTTGCGGACAAA
TACGATGTGCAAGTCGCTATCCACACAGACACTTTGAATGAAGCTGGTTGTGTAGAAGACACTATGGCTGCTATTGCCGG
ACGCACTATGCACACTTTCCACACTGAAGGCGCTGGTGGCGGACACGCTCCTGATATTATTAAAGTGGCCGGTGAACACA
ACATCCTACCCGCTTCCACTAACCCCACTATCCCTTTCACTGTGAATACAGAAGCCGAACACATGGACATGCTTATGGTG
TGCCACCACTTGGATAAAAGCATTAAAGAAGATGTCCAGTTCGCTGATTCAAGGATCCGCCCTCAAACCATTGCGGCTGA
AGACACTTTGCATGACATGGGGATTTTCTCAATCACCAGTTCTGACTCTCAAGCGATGGGCCGTGTGGGTGAGGTTATCA
CTAGAACTTGGCAAACAGCTGATAAAAACAAAAAAGAATTTGGCCGCTTGAAAGAAGAAAAAGGCGATAACGACAATTTC
AGGATCAAACGCTACTTGTCTAAATACACCATTAACCCAGCGATCGCTCATGGGATTAGCGAGTATGTAGGTTCAGTAGA
AGTGGGCAAAGTGGCTGACTTGGTATTGTGGAGTCCAGCATTCTTTGGCGTGAAACCCAACATGATCATCAAAGGCGGAT
TCATCGCGTTAAGCCAAATGGGCGATGCGAACGCTTCTATCCCTACCCCACAACCGGTTTATTACAGAGAAATGTTCGCT
CACCATGGTAAAGCTAAATACGATGCAAACATCACTTTTGTGTCTCAAGCAGCTTATGACAAAGGCATTAAAGAAGAATT
AGGGCTTGAAAGACAAGTGTTGCCGGTAAAAAATTGCAGAAACATCACTAAAAAAGACATGCAATTCAATGACACTACCG
CTCACATTGAAGTCAATCCTGAAACTTACCATGTGTTCGTGGATGGCAAAGAAGTAACTTCTAAACCAGCTAATAAAGTG
AGCTTGGCTCAACTCTTTAGCATTTTCTAG

Protein sequence :
MKKISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTG
IYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLAKGNTSNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKV
SLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 4e-157 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 4e-157 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-146 59
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-146 59
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-146 59
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-146 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_005779813.1 urease subunit beta VFG0270 Protein 0.0 99