Gene Information

Name : HPGAM_02680 (HPGAM_02680)
Accession : YP_005780259.1
Strain : Helicobacter pylori Gambia94/24
Genome accession: NC_017371
Putative virulence/resistance : Virulence
Product : CAG pathogenicity island protein 5
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 533116 - 535362 bp
Length : 2247 bp
Strand : -
Note : COG3505 Type IV secretory pathway, VirD4 components

DNA sequence :
ATGGAAGACTTTTTGTATAACGCCTTATACTTCATAGAGGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTGTTTTTCCTCTACAAATTCATAAAAACTCAAAAAAAGGTTTTTAAAGATAAAGCTAACCAGCCTCAAAAGAAAA
AAAGCTTTAAAGAAATCATTATAGATGGGCTGAAAGAAAGGGTTAAAACCTTTGGCTTTTGGTTGCAAGCGATACTATTA
CTATCCTATTCTTTTATCACATCAGGGTTATTTTTCTTGATTCTCTTAGGTAATTTTTATGATGATAATAAATTGCCTGA
GAGCGATGATGATCTTTTTGATATATGGGTCTATGCGATACAAGATTTTCCTGCATACTATTTTAAGGCACTCACTTTTA
GCTCGCTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATATTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGATATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGTAGCGC
GAGTTGGGAAACTGAAGAGAAAATGATCAAAGCCAAGCTTATCACACCCAACAATAAAAAACGCGCCTTTGACAAGCGAG
AGGTGATTGTAGGCAGGCGAGGTTTGGGGGATTTTATCGCTTACGCAGGACAGGCGTTCATTGGACTCATTGCCCCTACT
AGGAGCGGTAAGGGGGTGGGTTTCATCATGCCCAATATGATCAATTATCCTCAAAATATCGTTGTGTTTGATCCTAAGGC
TGACACTATGGAAACTTGCGGGAAAATCAGAGAGAAACGCTTCAACCAAAAAGTGTTCATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTGACTGAAGACATACTCTCTCAAATT
GACACACGCTTAAAAGGGCATGGCATGGTGGCTAGTGGAGGGGATTTTTCCACTCAAATCTTTGGATTGGCTAAGTTGGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTCTTTAGCAATCAAGCGCGAAACCTCTTTGTCATCAATTGCAATATTT
ACAGGGATCTCATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACCCCTACGATG
TTTTTCATAGGTTCTATGGCAAGCGGGATCAACCTGATTGATGAAGACACAAACATGGAAAAAGTCGTGTCTTTAATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGATAATCTAAGAGCGCTTAGTCCTGCCACTAGAAACATGTGGAATAACT
TTAAGACAATGGGTGGTGCTAGAGAAACTTATAGCTCGGTTCAAGGGGTATATACTTCAGCCTTTGCTCCTTATAATAAC
GCAATGATCAGGAATTTCACGAGCGCTAATGATTTTGATTTTAGGCGTTTAAGGATCGATGAGGTCAGCATTGGCGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGACCGATATTAGAGCTGTTTTTCAACGTGATGATTTATAGCAACCTGATTC
TGCCAATCCATGATCCACAATGCAAAAGAAGCTGCTTGATGCTCATGGATGAATTCACTTTGTGTGGCTATTTAGAGACC
TTTGTTAAAGCGGTAGGGATCATGGCAGAATACAACATGCGCCCTGCTTTTGTGTTTCAAAGTAAGGCACAATTAGAAAA
TGATCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTGAATATGTATTATGGGATCA
ACAACGATAACTACTATGAACATTTTGAAAAGCTTTCTAAAGTGTTAGGGAAATACACAAGGCAAGATGTGAGCCGAAGC
ATTGATGACAATACGGGTAAGACCAACACTTCTATCAGCAACAAGGAGCGGTTTTTGATGACCCCTGATGAATTGATGAC
TATGGGCGATGAGCTTATCATTTTAGAAAATACGCTCAAACCCATCAAATGCCACAAGGCGCTTTACTATGATGATCCTT
TCTTCACCGATGAGCTCATTAAGGTGAGTCCAAGCTTGAGCAAGAAATACAAATTGGGGAAAGTGCCTAATCAAGCAACA
TTTTATGATGACTTGCAAGCCGCTAAAACCAGAGGCGAATTGAGCTATGATAAATCTTTAGTGCCTGTGGGTTCAAGCGA
ACTGTGA

Protein sequence :
MEDFLYNALYFIEDYKLVVIFSFIGLIALFFLYKFIKTQKKVFKDKANQPQKKKSFKEIIIDGLKERVKTFGFWLQAILL
LSYSFITSGLFFLILLGNFYDDNKLPESDDDLFDIWVYAIQDFPAYYFKALTFSSLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWETEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVFIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDEDTNMEKVVSLMEFFGGEEDKSGDNLRALSPATRNMWNNFKTMGGARETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQAT
FYDDLQAAKTRGELSYDKSLVPVGSSEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cag5 YP_005779066.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03887.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13776.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD14023.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13830.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_003728740.1 cag pathogenicity island protein beta Virulence cag PAI Protein 0.0 99
HP0524 BAD13885.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03916.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 NP_207320.1 cag pathogenicity island protein (cag5) Virulence cag PAI Protein 0.0 99
HP0524 BAD13912.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13967.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
virD4 NP_223191.1 cag island protein, DNA transfer protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13995.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005774545.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03947.1 Cag5 Virulence cag PAI Protein 0.0 99
cag-beta AAF80195.1 Cag-beta Virulence cag PAI Protein 0.0 99
HP0524 BAD13803.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005777268.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03858.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13940.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0524 BAD14049.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
cag5 YP_005775727.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0524 BAD13857.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPGAM_02680 YP_005780259.1 CAG pathogenicity island protein 5 VFG0284 Protein 0.0 99