Gene Information

Name : HPGAM_00570 (HPGAM_00570)
Accession : YP_005779847.1
Strain : Helicobacter pylori Gambia94/24
Genome accession: NC_017371
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 114422 - 115564 bp
Length : 1143 bp
Strand : -
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGCGCATGCAAACCAAATTAATCCATGGGGGCATTAGTGAGGATGCGACAACGGGGGCGGTGAGCGTGCCTATTTATCA
GACTTCCACCTACCGCCAAGACGCCATAGGCCGCCATAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAGCTCATCGCCGATTTAGAAGGGGGGGTTAAGGGGTTCGCTTTCGCCTCTGGTTTAGCCGGGATCCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGTTATTGGGCGATGATGTCTATGGGGGGACTTTCCGCTTGTTTAACAA
AGTGCTTGTCAAAAACGGGCTTTCATGCACCATTATAGACACTAGCGACATATCCCAAATTAAAAAGGCTATCAAGCCCA
ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACCGATTTAGCGCAATGCGCCAGTGTCGCT
AAAGATCATAATTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGGGCGGA
CATTGTGGTGCATAGCGGCACAAAATACTTAGGCGGGCATAGCGATGTGGTTGCTGGGCTTGTAACCACCAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA
GGGATTAAAACGCTGGGATTGCGCATGGAAGCTCATCAAAAAAACGCCCTTTGCGTGGCTGAGTTTTTAGAGAAACACCC
TAAAGTGGAAAGGGTTTATTACCCGGGCTTGCCCACTCACCCTAATCACGAGCTAGCCAAAGCCCAAATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACTCTCAAAAATGACAGCGAGGCGACTCTTTTTGTAGAAAGCCTTAAATTATTCATTTTAGGC
GAGAGTTTGGGCGGGGTGGAAAGTTTGGTGGGGATTCCAGCGTTTATGACCCATGCGTGTATCCCTAAAGAGCAACGAGA
AGCCGCCGGAATCAGAGATGGTTTGGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC
AAGCGTTCGCTAAAATAAGCTAA

Protein sequence :
MRMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA
KDHNLLTIVDNTFATPYCQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNHELAKAQMRGFSGMLSFTLKNDSEATLFVESLKLFILG
ESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-98 55
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-99 55
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-72 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPGAM_00570 YP_005779847.1 cystathionine gamma-synthase BAC0207 Protein 7e-62 43