Gene Information

Name : guaA (HPGAM_05370)
Accession : YP_005780746.1
Strain : Helicobacter pylori Gambia94/24
Genome accession: NC_017371
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1090492 - 1092018 bp
Length : 1527 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACGCAGCTGATCGCTAGAAGATTGAGAGAGAGCGGGATTTATGCAGA
GATAGTCCCTTTTTTTGAAAGCGTAGAAAACATTCAAAAAAAAGCCCCTAAGGGATTGATTTTGAGCGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCCAATGAAAAAATCTTTGATTTGAATTTACCAATTTTAGGGATTTGCTACGGC
ATGCAGTATTTGGTGGATTTTTTTGGGGGGGTAGTGGCCTATGCGAATGAGCAAGAATTTGGTAAGGCTATTTTAGAAAT
CGCTCAAAATTCTGTGATTTTTGAAGGCGTGAAGATTAAAAGCCTTGTGTGGATGAGCCACATGGATAAAGTCATAGAAC
TGCCTAAAGGCTTCACTACCCTTGCAAAAAGCCCTAATTCCCCCCATTGTGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAAGGGGGTAAGATTTTAGAAAATTTTGCCTTTTTAGTTTGCGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATTGCGAGGCTGAAAGAACAAATTGCTAACGCTAAAGTGTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTGTTACACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGTTTGTTGCGTAAAAATGAAAAAGAAAAAGTCCAAGCGATGTTTAAAGACTTGCAAATCCCTTTAAA
CACGATAGACGCTAAAGAAGTCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AGACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAAAAACACCATTTAAAAGGCAAAATTGAGTTTTTAGCTCAAGGCACT
CTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACGCACCATAATGTGGGCGGACT
GCCTGAATGGATGGACTTTAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGCGCGCTTGTTGGGTAAAGAAT
TGGGCGTTAGTCAGGATTTTTTAATGCGCCACCCCTTTCCAGGACCTGGGCTTGCGATAAGGATTTTAGGCGAAATCAGT
GAGAGTAAGATCAAACGCTTGCAAGAAGCGGATGCTATTTTTATAGAGGAGCTTAAAAAAGCTAATTTGTATGACAAGGT
TTGGCAAGCCTTTTGCGTGCTATTGAATGTCAATTCTGTGGGGGTGATGGGGGATAATCGCACTTATGAAAACGCTATTT
GCTTGAGAGCAGTGAATGCGAGCGATGGTATGACAGCGAGCTTTTCTTTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AACCGCATCACTAATGAAGTGAATGGCATTAATAGGGTGGTGTATGATATTACCTCTAAGCCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYAEIVPFFESVENIQKKAPKGLILSGGPASVYAKDAYKPNEKIFDLNLPILGICYG
MQYLVDFFGGVVAYANEQEFGKAILEIAQNSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENGKIFGL
QFHPEVIQSEEGGKILENFAFLVCGCEKTWGMQHFAQREIARLKEQIANAKVLCAVSGGVDSTVVATLLHRAIKDNLIAV
FVDHGLLRKNEKEKVQAMFKDLQIPLNTIDAKEVFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEARLLGKELGVSQDFLMRHPFPGPGLAIRILGEIS
ESKIKRLQEADAIFIEELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVNGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-134 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-134 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-134 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-115 47