Gene Information

Name : metB (HPF57_0129)
Accession : YP_005776843.1
Strain : Helicobacter pylori F57
Genome accession: NC_017367
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 132459 - 133601 bp
Length : 1143 bp
Strand : +
Note : -

DNA sequence :
ATGCGCATGCAAACAAAATTAATCCATGGGGGCATTAGTGAGGACGCGGTAACGGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCGTCATAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAACTCATCGCCGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCTTCTGGTTTAGCTGGGATCCACGCC
GTTTTTTCCCTCTTGCAACCAGGCGATCATGTGCTATTGGGCGATGATGTCTATGGGGGGACTTTTCGCTTGTTCAATAA
AGTGCTTGTCAAAAGCGGGCTTTCTTGCACCATTATAGACACTAGCGATATATCCCAAATCAAAAAGGCTATCAAGCCCA
ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGCGCTAGTGTTGCT
AAAGATCATGGTTTGCTCACTATTGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGGGCGGA
CATCGTGGTGCATAGCGGCACTAAATATTTGGGTGGGCATAGCGATGTGGTCGCTGGGCTTGTAACCACTAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA
GGGATTAAAACGCTAGGATTACGCATGGAGGCCCACCAAAAAAATGCCCTTTGCGTGGCTGAGTTTTTAGAAAAACACCC
TAAAGTGGAGAAGGTTTATTACCCGGGTCTTCCCACTCACCCTAACCACGAACTGGCCAAAAAACAGATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACTCTCAAAAATGACAGCGAAGCGGTTGCTTTTGTAGAAAGCCTTAAACTATTCATTTTGGGC
GAGAGTTTGGGCGGAGTGGAAAGTTTGGTGGGGATTCCAGCGCTTATGACCCATGCGTGTATCCCCAAAGCACAACGAGA
AGCTGCTGGGATTAGAGATGGTCTGGTGCGCTTGTCTGTAGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC
AAGCGTTCACTAAAATAGGCTAA

Protein sequence :
MRMQTKLIHGGISEDAVTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQPGDHVLLGDDVYGGTFRLFNKVLVKSGLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA
KDHGLLTIVDNTFATPYCQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFILG
ESLGGVESLVGIPALMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFTKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-98 55
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-99 55
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 9e-74 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_005776843.1 cystathionine gamma-synthase BAC0207 Protein 1e-62 44