Gene Information

Name : HPLT_00570 (HPLT_00570)
Accession : YP_005772274.1
Strain : Helicobacter pylori Lithuania75
Genome accession: NC_017362
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 106182 - 107324 bp
Length : 1143 bp
Strand : -
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGCGCATGCAAACCAAATTAATCCATGGGGGCATTAGTGAAGACGCGACAACGGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCGCCACAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAACTCATCGCTGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCTTCTGGTTTAGCCGGGATTCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGTTATTGGGCGATGATGTTTATGGGGGGACTTTCCGCTTGTTTAATAA
AGTGCTTGTCAAAAACGGGCTTTCTTGCACCATTATAGACACTAGCGATATATCCCAAATCAAAAAGGCTATCAAACCCA
ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGTGCTAGTGTCGCT
AAGGATCATGGTTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTATCAAAACCCGCTTCTTTTGGGAGCGGA
CATTGTGGTGCATAGCGGCACCAAATACTTAGGCGGTCATAGCGATGTGGTCGCTGGGCTTGTAACCACCAATAATGAAG
CGCTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA
GGGATTAAAACGCTAGGATTACGCATGCAAGCCCATCAAAAAAACGCCCTTTGTGTGGCTGAATTTTTAGAAAAACACCT
TAAAGTGGAAAGGGTTTATTACCCGGGCCTTCCCACTCACCCTAATTACGAGCTAGCCAAAGCCCAAATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACTCTCAAAAATGACAGCGAAGCGGTTGCTTTTGTAGAAAGCCTTAAATTATTCATTTTAGGC
GAAAGTTTGGGCGGGGTGGAAAGTTTGGTGGGGATTCCGGCATTTATGACCCATGCGTGTATCCCTAAAGAACAACGAGA
AGCTGCAGGGATTAGAGATGGCCTGGTGCGCTTGTCTGTAGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC
AAGCGTTCGCTAAAATAGGCTAA

Protein sequence :
MRMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA
KDHGLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMQAHQKNALCVAEFLEKHLKVERVYYPGLPTHPNYELAKAQMRGFSGMLSFTLKNDSEAVAFVESLKLFILG
ESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-97 54
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-98 54
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-72 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPLT_00570 YP_005772274.1 cystathionine gamma-synthase BAC0207 Protein 1e-62 44