Gene Information

Name : ureB (HPSA_00370)
Accession : YP_005770707.1
Strain : Helicobacter pylori SouthAfrica7
Genome accession: NC_017361
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 73419 - 75128 bp
Length : 1710 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAGATTAGCAGAAAAGAATACGTATCTATGTATGGCCCTACTACAGGCGACAAAGTGAGATTGGGCGATACAGA
ACTGATTGCTGAAGTAGAACATGACTACACCATTTATGGCGAAGAACTTAAATTCGGCGGCGGTAAAACCCTAAGAGAAG
GCATGAGCCAATCTAACAACCCCAGCAAAGAAGAACTGGATTTAATCATCACCAACGCTTTAATCGTGGATTACACCGGT
ATTTATAAAGCGGATATTGGTATTAAAGACGGCAAAATCGCTGGCATTGGTAAAGGCGGTAACAAAGACATGCAAGATGG
CGTTAAAAACAATCTTAGCGTAGGTCCTGCTACTGAAGCGCTAGCCGGTGAAGGTTTGATCGTAACGGCTGGTGGTATTG
ACACACACATCCACTTCATTTCACCCCAACAAATCCCTACAGCTTTTGCAAGCGGTGTAACAACCATGATTGGTGGCGGA
ACCGGTCCTGCTGATGGCACTAATGCGACTACTATCACTCCAGGTAGAAGAAATTTAAAATGGATGCTCAGAGCGGCTGA
AGAGTATTCTATGAACTTAGGTTTCTTGGCTAAAGGTAACACTTCTAACGATGCGAGCTTAGCCGATCAAATTGAAGCCG
GTGCGATTGGCTTTAAAATCCACGAAGACTGGGGCACCACTCCTTCTGCAATCAATCATGCGCTAGACGTTGCGGACAAA
TACGATGTGCAAGTCGCTATCCACACAGACACTTTGAATGAAGCCGGTTGCGTAGAAGACACTATGGCTGCTATTGCCGG
ACGCACTATGCACACTTTCCACACTGAAGGCGCTGGCGGCGGACACGCTCCTGATATTATTAAAGTGGCCGGTGAACACA
ACATTCTACCCGCTTCCACTAACCCCACTATCCCTTTCACCGTGAATACAGAAGCCGAGCACATGGACATGCTCATGGTG
TGTCACCACTTGGATAAAAGCATTAAAGAAGATGTCCAGTTCGCTGATTCAAGGATCCGCCCTCAAACCATTGCGGCTGA
AGACACTTTGCATGACATGGGGATTTTCTCCATCACCAGTTCTGACTCTCAAGCGATGGGCCGTGTGGGTGAGGTTATCA
CTAGAACTTGGCAAACAGCTGACAAAAACAAAAAAGAATTTGGCCGCTTGAAAGAAGAAAAAGGCGATAACGACAACTTC
AGGATCAAACGCTACTTGTCTAAATACACCATTAACCCAGCAATCGCTCATGGGATTAGCGAGTATGTAGGTTCTGTGGA
AGTGGGCAAAGTCGCTGACTTGGTATTATGGAGTCCAGCATTCTTTGGCGTGAAACCTAACATGATCATCAAAGGCGGAT
TCATTGCGTTAAGTCAAATGGGTGATGCGAACGCTTCTATCCCTACTCCGCAACCGGTTTATTACAGAGAAATGTTTGCC
CACCATGGTAAAGCTAAATACGATGCAAATATCACTTTTGTGTCTCAAGCGGCTTATGACAAAGGCATTAAAGAAGAGTT
AGGGCTTGAAAGACAAGTATTACCGGTTAAAAATTGCAGAAATATCACTAAAAAAGATATGCAATTCAATGACACTACCG
CTCACATTGAAGTCAATCCTGAAACCTACCATGTGTTCGTGGATGGCAAAGAAGTAACTTCTAAACCGGCTAATAAAGTG
AGCTTAGCACAACTCTTTAGCATTTTCTAG

Protein sequence :
MKKISRKEYVSMYGPTTGDKVRLGDTELIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTG
IYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLAKGNTSNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKV
SLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-157 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-157 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-146 60
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-146 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-146 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-146 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_005770707.1 urease subunit beta VFG0270 Protein 0.0 99