Gene Information

Name : lysS (HMPREF4655_20424)
Accession : YP_005769555.1
Strain : Helicobacter pylori 35A
Genome accession: NC_017360
Putative virulence/resistance : Virulence
Product : lysine--tRNA ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 409783 - 411288 bp
Length : 1506 bp
Strand : +
Note : COG: COG1190; Pfam: PF01336, PF00152; InterPro: IPR002313

DNA sequence :
ATGTTTTCCAACCAATACATCCAACAACGCATCCATAAAGCCAACAGCTTGAGGGAAGAAGGGAAAAACCCTTATAAAAA
TGGCTTGAAACGAAGCCTTACAAACGCCGCTTTTTTAGAAAAATACGCCTATGTTAAGGATTTAGAAGAGCCTAAAGACA
AGGAAAAATGCGAGAGTATTGTAGGGAGGGTCAAGCTTTTGCGTTTAATGGGTAAGGCATGTTTTATTAAAATTGAAGAT
GAAAGCGCGATTTTGCAAGCTTATGTTTCGCAAAATGAATTGAATGATGAGTTTAAAAGCCTGAAAAAGCATTTAGAAGT
GGGCGATATTGTGTTGGTGAAAGGTTTCCCTTTTGCTACCAAAACCGGTGAATTAAGCGTTCATGCCCTAGAATTTCATA
TTTTAAGCAAAACCATTGTGCCTTTACCTGAAAAATTCCATGGACTGAGCGATATAGAATTACGTTACCGCCAGCGCTAT
TTGGATTTGATAGTCAATCCTAGCGTTAAAGATGTGTTTAAAAAACGCAGTTTGATTGTTTCTAGCGTGCGGAAATTCTT
TGAAACGGAAGGATTTTTAGAAGTGGAAACCCCCATGATGCACCCCATTCCTGGCGGGGCGAACGCAAGGCCTTTTATCA
CTTACCATAACGCTTTAGAAATTGAAAGGTATTTAAGAATCGCTCCAGAATTATACCTCAAACGCTTGATTGTGGGGGGT
TTTGAAGCGGTGTTTGAAATCAATCGTAATTTCAGGAATGAGGGCATGGATCACAGCCATAACCCCGAATTTACGATGAT
TGAGTTTTATTGGGCGTATCACACTTATGAAGATTTGATCGAACTCAGTAAGAGGCTATTTGACTACTTGCTAAAAACTT
TGAACTTACCTTCAAAAATCATTTATAACGATATGGAAGTGGATTTTAACCAAACGAGCGTGATTTCCTATTTGGACGCT
TTAGAAACAATAGGGGGCATTAGTAGGGATATTTTAGAAAAAGAAGACAGGCTTTTGGCTTATTTGTTAGAGCAAGGCAT
TAAAGTAGAGCCAAATCTCACTTATGGTAAATTGCTCGCTGAAGCGTTTGATCATTTTGTAGAGCACCAACTCATTAACC
CCACTTTTGTAACCCAATACCCCATTGAGATTAGCCCCCTAGCCAGACGCAACGATAGTAACCCTAATATTGCTGACAGG
TTTGAATTGTTTATTGCAGGGAAAGAAATCGCTAACGGCTTTAGCGAGTTGAACGATCCTTTAGATCAATTAGAACGCTT
TAAAAATCAAGTGGCTGAAAAAGAAAAAGGCGATGAAGAAGCCCAATACATGGATGAAGATTATGTGTGGGCGTTAGCCC
ATGGAATGCCCCCCACTGCAGGGCAAGGCATAGGCATTGATAGATTAGTGATGCTACTCACTGGGGCTAAAAGCATTAAA
GATGTGATTTTATTCCCAGCGATGCGTCCTGTTAAAAACGATTTTAATGTGGAGAGTGAAGAATAA

Protein sequence :
MFSNQYIQQRIHKANSLREEGKNPYKNGLKRSLTNAAFLEKYAYVKDLEEPKDKEKCESIVGRVKLLRLMGKACFIKIED
ESAILQAYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFATKTGELSVHALEFHILSKTIVPLPEKFHGLSDIELRYRQRY
LDLIVNPSVKDVFKKRSLIVSSVRKFFETEGFLEVETPMMHPIPGGANARPFITYHNALEIERYLRIAPELYLKRLIVGG
FEAVFEINRNFRNEGMDHSHNPEFTMIEFYWAYHTYEDLIELSKRLFDYLLKTLNLPSKIIYNDMEVDFNQTSVISYLDA
LETIGGISRDILEKEDRLLAYLLEQGIKVEPNLTYGKLLAEAFDHFVEHQLINPTFVTQYPIEISPLARRNDSNPNIADR
FELFIAGKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHGMPPTAGQGIGIDRLVMLLTGAKSIK
DVILFPAMRPVKNDFNVESEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-106 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_005769555.1 lysine--tRNA ligase VFG1668 Protein 3e-106 50